Alzheimer Disease Hypothesis

Depression is one of the most recurrently investigated psychological disorders within the area of medical R&D (Montorio & Izal, 1996). A number of exhaustive researches have been carried out to study its symptoms and impacts on different patients belonging to different personal and professional attributes and most of these researchers depicted that depression in the elderly people is very frequent and in spite of number of researches in this context, it is often undiagnosed or untreated. To add to this jeopardy, it has also been estimated that only 10% out of the total depressed elderly individuals receive proper diagnosis and treatment (Holroyd et al, 2000). And for that reason, an authentic

The disease called Alzheimer’s is the fourth leading cause of death in the United States (Weiner, 1987). It is estimated that the elderly population will double between now and 2030. During this period, the number of elderly will grow by an average of 2.8% annually (U.S. Census Bureau, 2001). By 2050, the number of people with Alzheimer’s is estimated to range from 11.3 million to 16 million (Alzheimer’s Association, 2005). These startling numbers should prompt an examination into one of the leading causes of death among this group of people. Understanding what Alzheimer’s is and the known causes of the disease are a good starting point. For those who have aging family members, knowing the risk factors and warning

According to the Alzheimer’s Disease International (ADI), dementia is one of the most prevalent disorders found among

One of the most prominent and perhaps most feared condition associated with aging is dementia. The family of disorders can cause individuals to lose their mind, reducing one from being a complex, thinking, feeling human being to being confused and vegetative, unable to recognize their loved ones. Serious dementia affects nearly 37 million people globally, but predictions of how those numbers will change over the next few decades are conflicting (textbook). Although we know dementia as to do with damage to nerve cells in the brain, there are ongoing studies looking at correlations between other health issues and these types of diseases.

Throughout history there have been reports of decreased memory and mental deterioration that accompanied old age. Alzheimer’s disease (AD) was named after Dr. Alois Alzheimer who described the symptoms in a woman in Germany in the 1907 but it was not until the 1970’s that AD was considered to be a major disorder and AD continues to be a major health concern worldwide (Reger, 2002).

"Depression and Alzheimer's | Caregiver Center." Alzheimer's Association. N.p., n.d. Web. 11 Jan. 2017. .

Alzheimer’s disease (AD) is the most common form of dementia known today. The term “dementia” refers to a variety of conditions that arise from the loss of nerve cell function and/or nerve cell death in the brain, including Alzheimer’s disease, vascular dementia, Parkinson’s disease, Creutzfeldt-Jakob disease and other types of mixed dementia. Although all types of dementia arise from neuronal damage and/or death, each form of dementia is associated with distinct brain abnormalities and symptom patterns. Once a patient has been diagnosed with dementia, a physician must conduct further tests in order to determine the exact form of dementia that is present. Recent research indicates that many individuals,

They can mimic the disease through both clinical presentation and also radiographic findings, such as computed tomography (CT) and magnetic resonance imaging (MRI). Depression is one of the major imitators of Alzheimer’s. Furthermore, approximately 30-50% of people with Alzheimer’s also simultaneously suffer from depression. Due to the negative effects of depression, such as memory and motor dysfunction, one disease is often mistaken for the other. As a result of this, the National Institute of Mental Health has developed a criteria for diagnosing depression with Alzheimer’s (Mayo Clinic on

Although Alzheimer’s Disease (AD) is the most widely known cause of dementia in the elderly population, there are many other explanations and clinical diagnoses that

Dementia, defined by the Alzheimer’s Association, is the overall term for diseases and conditions characterized by a decline in memory or other thinking skills that affects a person’s ability to perform everyday activities. More than 250,000 Americans will develop dementia (including Alzheimer 's) when they are sixty-five or older and at eighty-five the risk of developing Alzheimer’s is fifty percent. Since this disease was found in 1907 by Alois Alzheimer, there have been thousands of dollars, research, and clinical trials put into finding a cure for this horrible disease. This literature review examines the effects of the type of Dementia known as

The utilization of biomarkers for Alzheimer 's malady is as yet viewed as trial and is fitting just for use by specialists as of now. The rules call for approving and institutionalizing the utilization of biomarkers before they can be connected in a clinical setting, similar to a specialist 's office. Biomarkers for Alzheimer 's malady did not exist when the first criteria were produced in 1984, and have been considered seriously as of late. (Garrett, M. D., and Valle, R. (2016).

Dementia is one of the age-related disorders which commonly affect the aging elderly population (65 and over). In 2010, the approximate number of people who had dementia was 35.6 million and it is estimated to double every twenty years, to 65.7 million in 2030 and 115.4 million in 2050 respectively. The incidence of dementia every year is 7.7 million which equals to one new case every four seconds (World Health Organization [WHO], 2012). In 2011, the Canadian baby boom generation initially began to turn 65 and became part of the elderly population which significantly impacted the fertility rates (Rockwood & Keren, 2010). In Canada, the elderly population accounts for approximately 13% of the population and one in eleven has dementia (Stein-Parbury & Eliopoulos, 2014). The researchers have estimated that by 2036, it will account for 25% of the population and 28% by 2061 (Bartfay, Bartfay & Gorey, 2013). There are many forms of dementia that an individual can acquire. Alzheimer’s disease is one of the common forms of dementia in the elderly population (National Institutes of Health, 2013). Currently, approximately five million Americans have Alzheimer’s disease (WHO, 2012) from which two thirds account for women (Alzheimer’s Association, 2014). The reason behind more women having Alzheimer’s disease is merely due to the fact that women have higher life expectancy and old age contributes to higher risk for acquiring Alzheimer’s disease. It is apparent that Alzheimer’s disease

Dementia is a syndrome which is progressive in nature, characterized by impairment of memory and loss of intellectual ability.1 Decreased level of Acetylcholine in the brain, neuro-inflammatory reaction, rise in the oxidative stress and hypercholesterolemia have been reported to play an important etiological role in the memory decline.2 Alzheimer’s Disease (AD) is the most common form of dementia which is a progressive and a neurodegenerative disease characterized by the presence of senile plaques rich in insoluble aggregates of β amyloid and neurofibrillary tangles in the brain. AD has been estimated to account for 50–60% of dementia cases in persons over 65 years of age worldwide.3 Alzheimer’s Disease International

It is already established that late-life depression is associated with increased risk of dementia, but the temporal relationship between depression and development of

Abstract: Alzheimer’s disease (AD) is the most common neurodegenerative disorder of the central nervous system. Cur-