Alzheimer 's Disease : A Common Neurodegenerative Disease

When it comes to Alzheimer’s, I know firsthand how it affects individuals and their families. My great grandfather had Alzheimer’s for many years before his passing late last year, at age 92. Alzheimer’s is a disease that many individuals suffer with each year, but yet with all the advancements in modern medicine we still have no cure for it. There are different ways to conquer this disease, understanding the causes, knowing effects, and researching possible treatments.

The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat

Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.

Alzheimer’s is a disease in the brain that affects a person’s memory, thinking, and behavior. It is the most common form of dementia and is common in adults older than 65. More than five million Americans are being affected by Alzheimer’s at this moment. Alzheimer’s comes in three stages; early, middle, and advanced. The disease is caused by the shrinking of the brain due to many risk factors and genetics.

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

Alzheimer's seems to be a degenerative disease that affects everyone no matter the ethnic group one associates themselves with. Alzheimer's is a form of dementia, which is the general medical term for memory loss and the diminishing of intellectual abilities that eventually affects one's daily life. An ethnic group that is experiencing a growing rate of Alzheimer's is Japanese Americans. Several longitudinal studies of Japanese Americans have found rates of Alzheimer's Disease comparable to those found with older non-Latino white populations in the United States (Lee, Melichar, Musselman, & Yoo, 2015). Although studies have shown that rates are comparable for Japanese Americans versus the American majority, studies are consistently showing

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the most widespread age-related neurodegenerative diseases. Both diseases impact a considerable number of people, where AD occurs in around 10 percent of the population greater than the age of 65 while PD occurs in roughly 1 percent of the population above the age of 65. AD is considered to be the most widespread cause of dementia, characterised by the progressive memory and cognitive deficits which impair ones day to day activities. The pathological hallmark of AD comprises of extracellular accumulation of senile plaques consisting of mainly amyloid-beta (Aβ) peptides, along with neurofibrillary tangles which are composed of the phosphorylated tau protein, located in the hippocampus and cortex. Conversely, PD is considered to be the most widespread movement disorder that is characterised by symptoms such as rigidity slow movements, resting tremor and other instabilities. The extreme loss of dopaminergic neurones in the substantia nigra is what defines PD, as the loss of this nerve cell can be linked to Lewy bodies containing aggregates of a soluble protein called α-synuclein.

Alzheimer’s Disease • Alzheimer’s is the most common cause of dementia. • It occurs from changes in the nerve cells of the brain. • No one knows what causes Alzheimer’s. It cannot be cured and will not go away. • Signs include memory loss, confusion, poor judgment, and changes in language.

Alzheimer 's disease (AD) is an irreversible and incurable form of dementia characterized by rapid cell death, neurofibrillary tangles, and neuritic plaques (Cavanaugh, Blanchard-Fields, & Norris, 2008). Structures of the brain affected by rapid cell death includes the hippocampus, the cerebral cortex, and the forebrain (Cavanaugh et al., 2008). A definitive diagnosis of AD is made only at autopsy (Cavanaugh et al., 2008). As AD progresses, memory and ultimately self-identity are destroyed, however, interventions can improve the quality of life of older adults (Cavanaugh et al., 2008). Interventions in AD should focus on helping patients make the most effective use of their functioning (Cavanaugh et al., 2008). A non-pharmacological intervention by Bredesen (2014) appears to be restoring some cognitive function in some patients with AD (Dador, 2014). Bredesen (2014) asserts that some of the effects of cognitive decline can be reversed through his therapeutic program. Jimbo, Kimura, Taniguchi, Inoue, and Urakami (2009) also assert the potential of non-pharmacological interventions. They found that aromatherapy has the potential to improve cognitive function. Other non-pharmacological interventions such as exercise or physical activity (PA) have been studied for their effects in cognitive decline (Farina, Rusted, & Tabet, 2014; Tortosa-Martinez & Clow, 2012). This paper explores the effects of non-pharmacological interventions in cognitive decline associated with AD.

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by β-amyloid plaque formation caused by aggregation of β-amyloid42 within the brain leading to a progressive decline in cognitive function and memory loss (2). Hyperphosphorylated tau protein is occasionally found in brains of AD patients with advanced pathology however, it is not necessarily an indicator of AD but considered a sign of disease severity (2, 4, Kosik et al, 1986). AD is separated into two subcategories following the simple sporadic and familial disease classifications, early-onset AD (EOAD) which develops in individuals between 30 and 60+ years of age and late-onset AD (LOAD) which develops in individuals 60 years of age or older (2). Familial AD may

Marlene Targ Brill uses, in her book about Alzheimer's, Nancy Reagan's quote to describe this awful neurodegenerative disease. "Alzheimer's disease is a cruel disease that steals lives. It's hard to know what to expect. The years of exchanging memories of old age are gone. It's long, long good-bye" (Nancy Reagan, former First Lady, pg 10). Alzheimer's symptoms are most often confused with normal symptoms of aging, although they have a greater effect on daily life. Some of the symptoms are: poor judgment and decision making, inability to manage budget, losing track of the date or the season, difficulty having a conversation and misplacing things and being unable to retrace steps to find them.

Currently, in the world, there are about 47.5 million people living with the neurological disorder known as Alzheimer’s. Alzheimer’s disease was discovered by a German scientist known as Alois Alzheimer’s in the 21st century. Alzheimer’s is a disease which develops in many people around mid-adulthood. Alzheimer’s disease is when an individual’s brain starts to degenerate because of neuronal loss and also when the neurotransmitters decline their function. Alzheimer’s is when an individual is losing their memories because of their neurons touching each other and their messages are going everywhere because there is no synaptic gap. This is a serious problem.

Alzheimer is a disease that affects the elderly most. The disease was discovered by Dr. Alois Alzheimer in the year 1906 when he was examining a female’s brain. He found out that the woman displayed memory loss, language problems and some inexplicable changes in behavior. The disease was named after the doctor who was a German psychiatrist and a neuropathologist. Alzheimer’s disease is a degenerative brain disorder that leads to memory loss, personality changes, and language problems (Gilbert & Julie 2). The disease is mostly diagnosed in people over the age of 65 years, though there is a small minority of people under the age of 50 who get the disease. Studies show that 1% of a whole population aged between the ages 65-75 have severe

Gaming may be used for more than just simple entertainment. As studies have shown that playing video games and in this experiment Mario 64 have shown to help people with neurodegenerative diseases like Alzheimer’s dementia. What neurodegenerative diseases does is makes you lose the function of neurons which utilmy cause a loss to memory and decision thinking. And one of the big neurodegenerative diseases is Alzheimer’s dementia and symptoms include loss of memory behavioral problems and loss of self-care and eventually death. The point of the treatment is people who play video games have shown an increase gray matter in the right hippocampal formation. And the right dorsolateral prefrontal cortex and bilater cerebellum. So since playing video