Alzheimer 's Disease ( Ad )

Alzheimer disease (AD) is the most common cause of dementia in the elderly, accounting for 65–70% of all cases (Jellinger, Janetzky, Attems, & Kienzl, 2008). The other dementias are of the Parkinson 's group, the fronto-temporal group and the vascular group. The total worldwide yearly costs for the treatment and care of patients suffering from dementia are estimated to be around 250 billion US dollars. The lifetime risk for AD between the ages of 65 and 100 is 33% for men and 45% for women with an annual increase of 1–2% in the seventh decade to almost 60% in the 10th decade with doubling every 5 years (Jellinger et al., 2008). AD is incurable, and thus represents a major public health problem. AD represents a challenge to humanity due to its relatively recent discovery, progressive nature of the illness, and complex diagnosis.

Alzheimer’s disease is a common problem in today’s society and within the older population this disease makes up the largest form of dementia. Although it is a problem in mainly older people, this disease can still occur in the younger population also. People in their 30s-50s can be diagnosed with this disease, even though it is not as common as people in their 60s-90s. The number of people with Alzheimer’s in the U.S. is close to five million and is expected to double within the next 30 years. With our modern medicine and advancements one would think a cure would be available, however, getting to the cause of the disease is a major factor. The cause of Alzheimer’s disease is one that is very debatable and questionable and most likely is a result of multiple factors rather than one. The main issue with finding the cause is because this disease affects the brain and can

Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.

The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

In a study that was done called aging, demographics and memory study (ADAMS) it was found that older African Americans are two times more likely than older whites to develop Alzheimer or any other dementia. Some of the reasons that have been discovered as to why older African Americans are more common to have Alzheimer’s is because they are found to have higher rates of high blood pressure, diabetes, along with other vascular diseases. Some other factors that can affect who may end up with Alzheimer’s are lower level of education, and socioeconomic characteristics which are found to be more common in African Americans. In the health and retirement study (HRS) 80% of African Americans were found to have high blood pressure. Other risks that have been found to have increased risk of Alzheimer’s are those with lower educations, low income being below $18,000 a year, and

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.

Alzheimer's is a neurodegenerative disorder that affects the neurons within the brain, causing memory loss as well as language, and behavioral disturbances. An Alzheimer's brain contains Amyloid plaques that form toxic proteins which are called amyloid beta. The amyloid plaques start to spread throughout the brain causing tangles to form in the brain. The tangles are a form of twisted threads of protein. In compartment to a “normal” brain with an Alzheimer's brain, that Alzheimer's brain is remarkably smaller in size and contains fluid flied spaces.

Alzheimer’s disease (AD) is a neurodegenerative condition that affects the memory function, which is a huge public health concern among the elderly population. It has affected more than five million individuals in the United States and that number is expected to quadruple by the 2050 if interventions are not found. AD has a huge affect on the world not only by the number of deaths that it is causing but also the amount of health care costs reaching around 100 billion dollars. Because of the increase of AD throughout the globe, the aging population should consider the intake of certain vitamins and nutrients in their daily lives to possibly reduce or prevent the onset of AD.

Alzheimer’s disease (AD) is a disorder that is characterized by degeneration of the hippocampal and cortical neurons of the brain – causing memory impairment and a decline in cognitive abilities. The current study by Ghoneim et al.1 focuses on the role of three proteins in the pathogenesis of Alzheimer’s. Brain derived neurotrophic factor (BDNF) signaling is important for development and maintenance of normal neuronal circuits in the brain. Glial fibrillary acidic protein (GFAP) is expressed by astrocytes in the central nervous system in response to neuron damage. Ki-67 is a protein that is responsible for detecting cell proliferation. Ghoneim et al. designed their study to explore the effects of caffeine intake on the expression of these proteins in rats induced with AD.

Alzheimer’s disease is a very slowly progressive disease that occurs inside the brain in which is characterized by damage of memory. Also this type of disease can lead into interruption in language, problem solving, planning and perception. The chance of a person developing Alzheimer’s disease increases enormously after the age of 70 (Crystal, 2009). Also people who are over the age of 85 have over a 50 percent chance of developing Alzheimer’s disease. This type of disease is not at all normal in the aging process and is also not something that happens out of no where in a person’s life.

Alzheimer’s disease (AD) is a complex, multifactorial neurodegenerative disease that is currently being managed by symptomatic treatment. The affected areas include the central nervous system (CNS) which is made up of the brain and spinal cord. The brain is essential in managing our thoughts, cognitive abilities, and our ability to interact with the environment. AD patients are known to experience symptoms such as memory loss in the early stages which develop into speaking difficulties to eventually hallucinations. The commonly used AD treatments include Donepezil, rivastigmine, galantamine and memantine. Only the last two will be discussed in this essay and novel treatments. The current treatments for AD focus on relieving symptoms

Although Alzheimer’s disease (henceforth: AD) has been around since the 19th century or possibly even earlier and was at a point in time classified as senile dementia, it wasn’t until 1906 following Dr. Alois Alzheimer’s encounter with Auguste Deter at a Frankfurt asylum that the name of the disease was finally coined. Since then, major developments relating to the disease has taken place. In our report, we addressed some of the areas of the history, contemporary and prospects of the disease.

Abstract: Alzheimer’s disease (AD) is the most common neurodegenerative disorder of the central nervous system. Cur-