Alzheimer 's Disease ( Ad )

Alzheimer 's disease (AD) was discovered by a German doctor Alois Alzheimer in 1906 when he found amyloid plaques and neurofibrillary tangles in the autopsy of a woman who died of an unknown mental disease. The extracellular amyloid plaque deposits, composed of insoluble amyloid-Beta peptide were hypothesized to be the main etiological factor. “The most important abnormality is an excess of Amyloid-beta peptides brought about through either overproduction or failure in degradation.” (Uzun, Kozumplik, & Folnegović-Smalc, 2011) Later, it was discovered that intracellular neurofibrillary tangles composed of hyper-phosphorylated, helically-paired tau

Alzheimer’s disease has been around since 1901; a German psychiatrist Alois Alzheimer was the first man to identify and follow a case that is now known as Alzheimer’s disease. Alzheimer’s disease is involved in synaptic deterioration and neuronal cell death, and causes degeneration in the hippocampus and amyloid deposition in blood vessels, ultimately cell death is the cause of the disease. There are various ways that someone can acquire the Alzheimer’s, a few include; family history, obesity, and Down syndrome. Some symptoms of the disease are, memory loss, difficulty completing familiar daily tasks, confusion with

The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat

Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.

Alzheimer’s is a disease in the brain that affects a person’s memory, thinking, and behavior. It is the most common form of dementia and is common in adults older than 65. More than five million Americans are being affected by Alzheimer’s at this moment. Alzheimer’s comes in three stages; early, middle, and advanced. The disease is caused by the shrinking of the brain due to many risk factors and genetics.

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

In a study that was done called aging, demographics and memory study (ADAMS) it was found that older African Americans are two times more likely than older whites to develop Alzheimer or any other dementia. Some of the reasons that have been discovered as to why older African Americans are more common to have Alzheimer’s is because they are found to have higher rates of high blood pressure, diabetes, along with other vascular diseases. Some other factors that can affect who may end up with Alzheimer’s are lower level of education, and socioeconomic characteristics which are found to be more common in African Americans. In the health and retirement study (HRS) 80% of African Americans were found to have high blood pressure. Other risks that have been found to have increased risk of Alzheimer’s are those with lower educations, low income being below $18,000 a year, and

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

I think it is important for people to be aware of Alzheimer disease, especially adults who have a family member in late adulthood. If people were to have knowledge on how to help or treat someone who has Alzheimer disease it would be beneficial for both of them and it would make living together much easier. Many people don’t know what Alzheimer disease is “Alzheimer’s disease (AD) is the most common form of dementia. The risk of AD increases with age” (Takashi 2015). As someone ages they are most likely to get Alzheimer disease, this due to generalized degeneration of the brain. Alzheimer’s is a complex disease with multiple risk factors. Age and genetics are outside ones control, but many others are within your sphere of influence. These factors can be quite powerful when it comes to your brain health. I personally feel like I am well educated about this topic because school has done a very good job at teaching me how to deal and understanding people who have Alzheimer. Psychology has done a great job at helping understand this disease even further. The reason why I picked this topic was to try and find different ways to prevent and learn about Alzheimer disease because I have a great grandmother who has Alzheimer’s disease. My parents and grandparents would always tell me how difficult it is for them to help her out and have to deal with all her necessities. They would have to take turns taking care of her until they decided to hire someone to come take care of her.

Alzheimer’s disease is an irreversible, neurodegenerative disease that affects the brain causing progressive memory loss and destroys thinking skills. Alzheimer’s is the most common type of dementia, which is a general term used to describe disorders that affects brain functions. Alzheimer’s disease is caused by formations of plaques and tangles in the brain. A dangerous protein called beta-amyloid tends to build up over time in the brain. As this protein molecule accumulates, they start to form plaques, which can damage and destroy brain cells. While plaques affect the spaces between the brain cells, an abnormal protein known as “tau” starts affecting inside the brain cell itself. “Tau tangles can interfere with the transportation of nutrients in and out of the cells, causing brain cells to degenerate and die” (Kosik & Bowman, 2015, p. 5). Some common symptoms for Alzheimer’s include memory loss, constantly misplacing things, unable to remember the names of family members, unable to communicate properly, and losing the ability to complete simple daily tasks. Alzheimer’s disease is a fatal disease, but patients don’t die from the disease itself. Advanced Alzheimer’s increases vulnerability and increases the chance of developing infections that soon lead to death.

Alzheimer’s is a brain disease and is not a part of aging. It affects memory and learning as people get older. There is a stage called mild cognitive impairment which is not dementia but forgetting things is common in this stage. In the moderate stages a person with Alzheimer’s may began to repeat stories. A person can live on average eight to ten years. Alzheimer’s affect 4.5 million and this number is excepted to rise because of the baby boomer population.

Alzheimer 's disease(AD) wrecks memory and other essential mental capacities. Research has shown that numerous individuals with dementia, particularly those who are sixty-five or older, have brain impairments. All through the numerous periods of Alzheimer 's disease, people appear to show any indication, yet harmful changes are occurring in the cerebrum. An unnatural deposit of proteins structure amyloid plaques and tau tangles all through the brain, and once the active neurons quit working, they lose contact with different neurons, and they eventually die. Studies have also shown to slow down the rate of the developing, evolving Alzheimer 's disease. Supplements are significant because of the absence of new medications to treat elderly

Alzheimer’s is the most common form of Dementia. There is said to be 50% to 80% of Dementia cases. Alzheimer’s Disease is a progressive neurodegenerative disease. Neurodegenerative is “degenerative nerve diseases affect many of your body's activities, such as balance, movement, talking, breathing, and heart function. Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is not known.” (Medline Plus, n.d.) Neurodegenerative disease is the abnormalities or death of neurons. “In the early-stage of AD, cognition and the ability to acquire new memories are impaired. In the later stages, symptoms include

In 1995, the Taub Family Foundation supplemented the ADRC grant which expanded the growth and renaming the institute to The Taub Institute for Research on Alzheimer's disease and the Aging Brain(TAUB). Under Drs. Richard Mayeux and Michael Shelanski’s direction, TAUB operates as an independent department at Columbia University, promoting and administering research projects related to Alzheimer's disease in departments across Health Sciences and Morningside campuses. TAUB’s research collaborators

Alzheimer’s disease is the leading form of dementia within the world’s elderly population and given that there exists an ever increasing percentage of the elderly population within society, understanding this neurodegenerative disease has become more important than ever. It is a disease associated with subcortical temporal lobe structures such as the Hippocampus, the Entorhinal Cortex, the Amygdala, the Thalamus, among others. Clinically, those millions of individuals suffering from the disease experience episodes of irreversible memory loss, changes in personality and confusion (among a plethora of other symptoms). Physiologically, the disease is characterized by the accumulation of insoluble amyloid beta plaques, derived from the amyloid precursor protein (APP). Another characteristic marker for Alzheimer’s dementia is the Hyper-phosphorylation of the Tau protein which then aggregates to form insoluble neurofibrillary tangles (NFTs), that inhibit a cell’s ability to regulate the stabilization of the microtubule component tubulin.