Alzheimer 's Disease And Its Effects

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Alzheimer’s Disease accounts for sixty to seventy percent of dementia cases. The disease starts slowly and gets worse over time. The most common symptoms are short term memory loss, trouble with language , moods swings , and loss of movement. Communication networks are controlled by neurons . Neurons are the chief cells that get destroyed by Alzheimer’s disease. In the brain, neurons connect and communicate at synapses where tiny bursts of chemicals called neurotransmitters carry info from one neuron to another neuron. Alzheimer’s disease disrupts this process and destroys synapses damaging the brains communication system ( Alzheimer’s Association, 2014). Alzheimer’s drugs work by regulating the…show more content…
The first is Donepezil. The drug is very potent and it works by inhabiting AChE , the important neurotransmitters (Hodis, 2014). The drug helps reverse the decrease in brain function (Hodis, 2014). The second is Rivastigmine. It is approved to treat mild to moderate cases of Alzheimer’s Disease (Hodis,2014). The medicine is very simple. It improves mental function by decreasing the amount of neuronal lass and increasing amount of natural substances in the brain (Canner, 2014). The third drug is Galantomine. This drug is also prescribed for mild to moderate cases as well . It is a cholinesterase inhibitor meaning it does almost the same as the previous drug because it controls certain substances in the brain (Johnson, 2009). Alzheimer’s Disease is the degeneration of the cerebral cortex resulting in diffuse cortical atrophy (Johnson, 2009). The three main brain parts that Alzheimer’s disease affects are the cerebrum, cerebellum, and the brain stem (Alzheimer’s Association, 2014). When the inflammation and build-up gets to those parts of the brain it starts to break down the tissue , and when this happens brain cells decrease and neuronal loss begins (Alzheimer’s Association, 2014). Alzheimer’s disease is the build up of amyloid plaques between nerve cells . Amyloid is a protein and beta amyloid is a protein fragment cut from another protein. In a healthy brain these plaques and in a
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