“Alzheimer’S From A New Angle: A Radical New Approach To

Alzheimer’s Disease is a progressive neurological disease; it often attacks the brain tissues causing memory loss of one’s identity and regular behaviors. Statistics indicates that the rate of predicted people to get Alzheimer’s will increase briskly as time goes on. There are currently no cures for such disastrous disease, but there are currently approved treatments available that can help people within the early stages of Alzheimer’s. Once the disease is too far along, deteriorated brain cells are nearly impossible to revived or regenerate without stem cells, which have not been successfully ascertain. Research and medical trials are being conducted all over the world hoping to find the starting cause of it in

Alzheimer’s disease is a common problem in today’s society and within the older population this disease makes up the largest form of dementia. Although it is a problem in mainly older people, this disease can still occur in the younger population also. People in their 30s-50s can be diagnosed with this disease, even though it is not as common as people in their 60s-90s. The number of people with Alzheimer’s in the U.S. is close to five million and is expected to double within the next 30 years. With our modern medicine and advancements one would think a cure would be available, however, getting to the cause of the disease is a major factor. The cause of Alzheimer’s disease is one that is very debatable and questionable and most likely is a result of multiple factors rather than one. The main issue with finding the cause is because this disease affects the brain and can

Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.

Many believe that Alzheimer’s is a non-lethal disease, however, they couldn’t be more wrong. Alzheimer’s is a disease that leaves no survivors. It is lethal and has absolutely no mercy towards any one. It does not discriminate between race or gender, rich or poor. Anyone can be a target. So much, that it is now the sixth leading cause of death and it continues to rise each year (Ryan). Yet, the scariest thing about Alzheimer’s, is not just the memory loss, but also the fact that it has no cure and is irreversible. All hope, however, is not lost. New research has shown that if caught at a very early stage, the rate of deterioration of the brain due to Alzheimer’s, can be slowed down through treatments and therapy (Robinson). Although it is no cure, it can buy more time with a loved one diagnosed with this mindless killer. By catching Alzheimer’s at an early stage and looking out for the symptoms, one can slow down the deadly effects of Alzheimer’s.

Alzheimer’s causes degeneration of brain tissue and nerve cells. With less nerve cells present, it becomes harder for the brain to communicate with the body and function properly.

Alzheimer’s Disease (AD) is the most common type of dementia and the sixth-leading cause of death in the United States. This neurological condition is brought on by the malfunction or death of neurons in the brain, causing changes to one’s memory, behavior, and ability to think and reason logically and clearly. There is no cure for the disease and very little available to treat the symptoms. While AD was discovered over 100 years ago by German psychiatrist Alois Alzheimer, it has only been in the last few decades that research and science have started to understand the inner workings of the neurological degeneration and possible hypothesis as to its cause. However, the physiologic changes that trigger the change in neurons still remains unknown. AD worsens as it progresses and life expectancy following diagnosis is approximately seven years; fewer than three percent of individuals will live more than 15 years after their diagnosis (Mölsä, Martlla, Rinne, 1995).

Alzheimer’s disease is a progressive condition where the neurons degenerate in the brain, while the brain substance shrinks in volume. Alzheimer’s is also the number one cause of dementia. When it was first noticed, Alzheimer’s was thought to be a pre-senile disease, but now it is known to be responsible for seventy-five percent of the dementia cases in people over sixty-five years of age. Alzheimer’s disease usually causes several years of personal and intellectual decline until death. Because there is an increasing number of elderly citizens in the United States, research into the causes and possible cures for the disease is on the rise (1).

Alzheimer's Disease is a condition that affects 50% of the population over the age of eighty five, which equals four million Americans each year. It is becoming an important and high-profile issue in today's society for everyone. There are rapid advancements being made in the fight against this disease now more than ever, and the purpose of this essay is to educate the public on the background as well as the new discoveries. There are many new drugs that are being tested and studied every day which slow down, and may even halt the progress of the disease.

The dilemma of approved drugs for Alzheimer's only mask the symptoms of the disease, but do not treat the primary disease or many medications delay the progression and also cause side effects in a substantial number of treated patients. A novel Alzheimer's drug would actually treat the underlying disease; either delay or inhibit cell damage which ultimately leads to the emphasis of the associated symptoms.

The Alzheimer's disease Research Center (ADRC) at Columbia began in the late 1980’s when Drs. Richard Mayeux and Michael Shelanski’s common interest in Neurological Degenerative Disorders and their distinct treatment methods brought them together.

The life expectancy is now doubled from the last century in the developed countries due to the revolution progress in medicine and health mainly to chronic diseases. Alzheimer’s disease (AD) is one of the most well-known and familiar diseases in the modern societies AD was first reported by Alois Alzheimer in 1907.The AD is the most common type of dementia and a neurodegenerative disease characterized by the damage of nerve cells in the cerebral cortex. The health statistics report that AD disease affects more than 50 million people worldwide in 2003, it is expected this number to increase to 114 million by 2050.(1) It is reported that AD disease affect one in three people over the age 85.(2) The symptoms of AD include depression, apathy, anxiety, agitation, aggression, delusions, hallucinations, wandering, and inappropriate sexual behaviours.(3) AD patients suffer from decrease in cognitive function and short term memory. AD is characterised by the formation of insoluble clumps of protein or plaques, formed by proteins known as β-amyloids. These attach to the cell surface of neurons and disabled nerve transmission. These plaques have been demonstrated to contain relatively high levels of Zn2+, Cu2+ and Fe3+ (1 mM, 0.4 mM and 1 mM respectively).(4) While the precise role of these metals is still uncertain, they appear to bind to so-called β-amyloid peptides that constitute the bulk of plaque deposits. Cu2+

The brain contains 100 trillion synapses. They allow signals to travel rapidly and constantly through the brain’s circuits, creating the cellular basis of memories, thoughts, sensations, emotions, movements and skills. In Alzheimer’s disease, information transfer at synapses will begin to fail, the number of synapses decreases and neurons eventually die. The accumulation of beta-amyloid outside neurons will interfere with the neuron-to-neuron communication of

Alzheimer’s, a common form of dementia, causes memory loss and other cognitive abilities that interfere with daily life. Alzheimer’s is a progressive disease that worsens over time. In its early stages, patients display symptoms of memory loss and eventually leads to stages where a person can no longer identify the environment they are in. although there is no cure for Alzheimer’s, there are treatments the can temporarily slow the progress of dementia. Because Alzheimer’s is considered one of the leading causes of death in the United States, it is important to find alternative treatments that can stop its development.