Alzheimer's Degenerative Disease

Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.

Alzheimer’s disease is the progressive loss of memory and mental functions. The disease affects memory, thought control, language, and other cognitive functions. The disease typically appears with old age and is often found age 60. Alzheimer’s causes the brain to develop clumps and tangles fibers in the brain tissue along with the loss of neuron connections. Throughout the brain, proteins are abnormally distributed and they form tangled bundles of fibers and amyloid plaques. Some neurons fail to function properly and lose their connections, which are necessary for the transmission of messages to the body. The hippocampus is the key brain structure in the formation of memories and often experiences the first signs of damage.

Alzheimer’s is a disease in the brain that affects a person’s memory, thinking, and behavior. It is the most common form of dementia and is common in adults older than 65. More than five million Americans are being affected by Alzheimer’s at this moment. Alzheimer’s comes in three stages; early, middle, and advanced. The disease is caused by the shrinking of the brain due to many risk factors and genetics.

The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

as the sixth-leading cause of death in the United States and the fifth leading cause of death for individuals age 65 and older. While living with the disease an individual may face years of ill health as the disease progresses over time. Alzheimer’s is a terminal a brain disease that affects an extensive number of Americans. Alzheimer's is the most common type of dementia. Although the disease itself can be associated with aging; it is not synonymous with aging (Grossberg & Karmat, 2011). The relevance of the previous statement is significant to African Americans because they tend to associate aging with a decline in memory; hence they are less likely to

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

“There is one thing Alzheimer 's cannot take away, and that is love. Love is not a memory - it 's a feeling that resides in your heart and soul.” (Fade to Blank). The human brain is a remarkably complex organ that processes, stores, and recalls information. “Alzheimer 's disease (AD) is a slowly progressive disease of the brain that is characterized by impairment of memory and eventually by disturbances in reasoning, planning, language, and perception. Many scientists believe that Alzheimer 's disease results from an increase in the production or accumulation of a specific protein (beta-amyloid protein) in the brain that leads to nerve cell death.” (Crystal). It is the most common form of dementia, accounting for 50 to 80 percent of dementia cases, and currently has no cure. (# 3) Research continues to be done to develop better ways to care for those affected with the disease, as well as to find support for family members, friends, and caregivers. Alzheimer’s is a devastating illness that is not a normal part of aging. In order to find a cure, awareness needs to increase to improve understanding, develop effective treatments, and to essentially prevent the disease.

Dementia, known as one of the world 's current pandemics, is estimated to be the fourth most common cause of death in the developed country, second only to cardiovascular, cerebrovascular diseases and cancer. With the aging population, dementia has gradually become a serious threat to the health of the elderly people in Australia.

“Instead of labeling it Alzheimer’s, Dementia differs because it can happen any age.” In 2015, the Alzheimer’s Disease International estimated that about 46.8 million people worldwide live with dementia and these statistics will most likely double every twenty years. The most rapid growth of dementia in the elderly is currently taking place in China, India and the other surrounding Asian countries due to them being developing countries.

I think it is important for people to be aware of Alzheimer disease, especially adults who have a family member in late adulthood. If people were to have knowledge on how to help or treat someone who has Alzheimer disease it would be beneficial for both of them and it would make living together much easier. Many people don’t know what Alzheimer disease is “Alzheimer’s disease (AD) is the most common form of dementia. The risk of AD increases with age” (Takashi 2015). As someone ages they are most likely to get Alzheimer disease, this due to generalized degeneration of the brain. Alzheimer’s is a complex disease with multiple risk factors. Age and genetics are outside ones control, but many others are within your sphere of influence. These factors can be quite powerful when it comes to your brain health. I personally feel like I am well educated about this topic because school has done a very good job at teaching me how to deal and understanding people who have Alzheimer. Psychology has done a great job at helping understand this disease even further. The reason why I picked this topic was to try and find different ways to prevent and learn about Alzheimer disease because I have a great grandmother who has Alzheimer’s disease. My parents and grandparents would always tell me how difficult it is for them to help her out and have to deal with all her necessities. They would have to take turns taking care of her until they decided to hire someone to come take care of her.

When it comes to Alzheimer’s, I know firsthand how it affects individuals and their families. My great grandfather had Alzheimer’s for many years before his passing late last year, at age 92. Alzheimer’s is a disease that many individuals suffer with each year, but yet with all the advancements in modern medicine we still have no cure for it. There are different ways to conquer this disease, understanding the causes, knowing effects, and researching possible treatments.

Alzheimer’s disease is the 6th leading cause of death in America. It kills more than breast cancer and prostate cancer combined. Alzheimer’s accounts for 70-80% of dementia cases. By the age of 65, 1 in 9 people are diagnosed and by the age of 85, 1 in 3 people will have the disease. According to the Alzheimer Association, 5 million people in American have Alzheimer’s. Alzheimer’s starts to form 20 years prior to being diagnosed. Learning about Alzheimer’s can help families understand how Alzheimer’s is more than just memory loss, it is an incurable mental disease.

In a study that was done called aging, demographics and memory study (ADAMS) it was found that older African Americans are two times more likely than older whites to develop Alzheimer or any other dementia. Some of the reasons that have been discovered as to why older African Americans are more common to have Alzheimer’s is because they are found to have higher rates of high blood pressure, diabetes, along with other vascular diseases. Some other factors that can affect who may end up with Alzheimer’s are lower level of education, and socioeconomic characteristics which are found to be more common in African Americans. In the health and retirement study (HRS) 80% of African Americans were found to have high blood pressure. Other risks that have been found to have increased risk of Alzheimer’s are those with lower educations, low income being below $18,000 a year, and

Neurodegenerative disease is a type of neurological disorder that primarily affects the brain functioning due to progressive deterioration of neurons, protein misfolding and deposition of proteins, plaques, oxidative stress, etc. [1, 2, 3]. It includes a wide range of diseases such as Alzheimer’s, Parkinson’s, ALS and Huntington’s disease, each having its own hallmark characteristic and mechanism that eventually leads to neuronal death. Millions of people worldwide are affected by these diseases; around 5.3 million people in America alone have been diagnosed with Alzheimer’s[4]and the annual incidence rates of Parkinson’s is estimated to be 14 per 100 000 people in the total population, 160 per 100 000 people aged 65 years or older in high-income countries[5]. Furthermore,