New evidence states a viral infection brings Alzheimer’s to light. A recent editorial from the Journal of Alzheimer’s Disease shifts focus from immune system suppression to a viral infection. Dr. Douglas Kell, a professor at the University of Manchester’s School of Chemistry, claims, “We are saying there is an incontrovertible evidence that Alzheimer’s disease has a dormant microbial (viral) component. We can’t keep ignoring all of the evidence” (Knapton). Viruses are commonly found in the brains of elderly people. In most cases, they have all of their bodily functions. Around two-thirds of people will contract the viral infection herpes at some point in their lifetime. Herpes has been known to damage the central nervous system in humans.
The symptoms of Alzheimer’s are extremely detrimental to the individual whom it affects, as the disease attacks the brain cells and their connections. As the illness progresses, many
In the United States there are approximately 5.4 million people living with Alzheimer’s. Every sixty-nine seconds a person is diagnosed. This is an ongoing issue, and unless something is done, sixteen million people will be affected by 2050 (Latest).
In February of 2000, I lost my grandmother to Alzheimer's disease. She was diagnosed with the disease just less than two years prior to her death. Throughout that time, I watched changes in my grandmother that made her seem like an entirely different woman to me. She gradually began losing her short-term memory and we began to see signs of her long-term memory degrading too. It began to get harder and harder to take her out into public without being afraid of what would happen next. Her emotions would fluctuate with the changing of each minute it seemed. Physically she became weaker and weaker and would often scare us with falling while she would be walking. Eventually she had to be moved into the
There are about 45 million people worldwide affected by this dreadful disease (Crous-Bou). However, this isn’t cancer or heart disease. This is Alzheimer’s Disease. It’s the disease that has no sympathy towards anyone, not even my beloved grandmother. My grandmother, who I call Tita, has been diagnosed with Alzheimer’s Disease and has been dealing with symptoms for a few years now. Whenever she’s living with us (she lives with both her daughters at different times), she always forgets the simplest of things, such as her granddaughter’s name or even what day of the week it is. When these questions are asked, I can’t help but feel pity towards my Tita. My mother had told me about my Tita having this disease, but what surprised me more was the lack of treatments and preventions that also came with it. There should be more effective research completed on the preventions and treatments of Alzheimer’s Disease in order to get closer to a final cure for the patients.
Alzheimer disease (AD) is the most common cause of dementia in the elderly, accounting for 65–70% of all cases (Jellinger, Janetzky, Attems, & Kienzl, 2008). The other dementias are of the Parkinson 's group, the fronto-temporal group and the vascular group. The total worldwide yearly costs for the treatment and care of patients suffering from dementia are estimated to be around 250 billion US dollars. The lifetime risk for AD between the ages of 65 and 100 is 33% for men and 45% for women with an annual increase of 1–2% in the seventh decade to almost 60% in the 10th decade with doubling every 5 years (Jellinger et al., 2008). AD is incurable, and thus represents a major public health problem. AD represents a challenge to humanity due to its relatively recent discovery, progressive nature of the illness, and complex diagnosis.
Alzheimer’s Disease is a disease of the future. With the growing aged population, this disease, which affects primarily the elderly, will become of increasing relevance to the medical profession. Also, the high frequency of Alzheimer’s, and the high cost in labor, money, and material of caring for its victims shall put considerable burden on the society as a whole. Here, however, these issues are not going to be debated. Instead the pathology of Alzheimer’s will be reviewed to the extent it is known today.
In 1901, a fifty one year old woman named Frau Auguste D. was admitted to a psychiatric hospital in Frankfurt, Germany. She had an unusual bunch of symptoms. While she had no history of prior psychiatric illness, her husband had noticed that Frau D. was becoming increasing paranoid, hallucinatory, agitated, disoriented, and having increasing difficulties with language functions and memory.
The call came at 9:05 p.m. on January 20, 2004. Mom had just finished telling the news about the girl's grandfather. He had Alzheimer's Disease and was not doing well at all. The ruling was that he probably would not make it through the night. She knew exactly what the news was the moment her mom said, "No." After the news came, the decision was made they would leave the next day to attend the funeral.
The disease called Alzheimer’s is the fourth leading cause of death in the United States (Weiner, 1987). It is estimated that the elderly population will double between now and 2030. During this period, the number of elderly will grow by an average of 2.8% annually (U.S. Census Bureau, 2001). By 2050, the number of people with Alzheimer’s is estimated to range from 11.3 million to 16 million (Alzheimer’s Association, 2005). These startling numbers should prompt an examination into one of the leading causes of death among this group of people. Understanding what Alzheimer’s is and the known causes of the disease are a good starting point. For those who have aging family members, knowing the risk factors and warning
Nice work on your discussion board. Herpes Simplex Virus (HPS) 1 is currently being studied for a potential connection with the development of Alzheimer’s. The form of dementia is currently being studied with no definitive cause known. Recently studies have linked the neurotropic virus which often affects 90% of the population with the development of Alzheimer’s (Lövheim et al., 2015). The current hypothesis is based on the weakening of one’s immune system with age and the progression of HSV1 through the trigeminal nerve to the meninges via the olfactory tract creating an infection within the brain (Lövheim et al., 2015). The progression of the infection leads to inflammatory changes specifically changes on the cellular level creating
It is inevitable that eventually each of us will grow old and begin to face more and more health problems as our age rises. Elderly people are challenged by many illnesses and diseases that unfortunately, are incurable. One disease that becomes more common as people age is Alzheimer’s disease. Alzheimer’s a common cause and a form of dementia and can severely damage a patient’s cognitive functions and can ultimately cause death. Living with Alzheimer’s disease can be saddening for both the sufferer and the family. Family and friends will find it very hard to cope when a loved one begins slipping away and losing memory of who they are.
Alzheimer's Disease is a condition that affects 50% of the population over the age of eighty five, which equals four million Americans each year. It is becoming an important and high-profile issue in today's society for everyone. There are rapid advancements being made in the fight against this disease now more than ever, and the purpose of this essay is to educate the public on the background as well as the new discoveries. There are many new drugs that are being tested and studied every day which slow down, and may even halt the progress of the disease.
Alzheimer’s disease slowly steals a person’s dignity and erases precious memories. The “Alzheimer’s Disease Guide”, found on WebMD explains that tasks become more difficult to do often leading to confusion and behavior changes. The article further explains the progression of the disease also brings hardship to family and friends (1). To best cope with Alzheimer’s we must better understand the disease.
Alzheimer is a disease that affects the elderly most. The disease was discovered by Dr. Alois Alzheimer in the year 1906 when he was examining a female’s brain. He found out that the woman displayed memory loss, language problems and some inexplicable changes in behavior. The disease was named after the doctor who was a German psychiatrist and a neuropathologist. Alzheimer’s disease is a degenerative brain disorder that leads to memory loss, personality changes, and language problems (Gilbert & Julie 2). The disease is mostly diagnosed in people over the age of 65 years, though there is a small minority of people under the age of 50 who get the disease. Studies show that 1% of a whole population aged between the ages 65-75 have severe
An emerging area of research focus on the investigation of viral infections involved in neurodegenerative diseases. Data suggests that viral infections promote hallmark events seen in neuronal degeneration such as in Alzheimer's Disease (AD). In AD, protein aggregates of β-amyloid peptides forming plaques and neurofibrillary tangles composed of hyperphosphorylated tau has been shown to impair brain functions. Areas affected are the hippocampus and cerebral cortex responsible for cognitive and locomotor skills. Other contributing factors to neuronal degeneration includes oxidative stress, and modifications to autophagic and apoptotic pathways. This paper looks at herpes simplex type-1 involvement in AD.