Alzheimer's Disease

In times past many people thought that memory loss was a normal occurrence for elderly people. This thinking was major reason for why Alzheimer’s disease was not caught until very later in the stages. Alzheimer’s disease is not a normal part of aging. After heart disease, cancer, and strokes, Alzheimer’s is the most common cause of death in adults in the Western world. “It is estimated that 4.5 million Americans over the age of 65 are affected with this condition. After the age of 65, the incidence of the disease doubles every five years and, by age 85, it will affect nearly half of the population” (Robinson).

Alzheimer’s disease is a common problem in today’s society and within the older population this disease makes up the largest form of dementia. Although it is a problem in mainly older people, this disease can still occur in the younger population also. People in their 30s-50s can be diagnosed with this disease, even though it is not as common as people in their 60s-90s. The number of people with Alzheimer’s in the U.S. is close to five million and is expected to double within the next 30 years. With our modern medicine and advancements one would think a cure would be available, however, getting to the cause of the disease is a major factor. The cause of Alzheimer’s disease is one that is very debatable and questionable and most likely is a result of multiple factors rather than one. The main issue with finding the cause is because this disease affects the brain and can

The disease stem cells could fix is called Alzheimer’s Disease (AD). The reason I chose this topic is because I have seen first hand how badly someone who suffers from Alzheimer’s Disease is affected in their daily lives. This disease completely takes over their lives and they turn into a completely different person who can hardly function. AD is very tough on the loved ones of the person suffering from it because that person, most of the time has no idea what is going on or who their loved ones are. The memories for people with AD is completely gone and even the simplest tasks such as remembering to use the bathroom becomes difficult. The way stem cells could be feasible is because stem cell-based therapies could potentially treat

Alzheimer 's disease (AD) is a progressive degenerative disease of the brain from which there is no recovery. There are three brain abnormalities that are the hallmarks of the Alzheimer’s disease is initially caused by plaques buildup in the brain’s neurons as illustrated in figure 1. The support structure that allows the flow of the nutrients through the neurons gets damaged and ultimately there is loss of connection among the neurons and they die off (National Institute of Health, 2015). This causes the brain tissue to shrinks, which is called atrophies. All this ultimately lead the victim of this disease to face difficulties in governing emotions, recognize errors and patterns, coordinate movement, and remember. Ultimately, a person with AD loses all memory and mental functioning.

Alzheimer’s Disease has been one of the top leading causes of death in our country. It is understood that this disease is identified as an excess of the protein amyloid-ß within an increase of plaque (Seneff, Wainwright, and Mascitelli, 2010). Additionally, as the brain ages, it gets used to the inflammation and oxidative stress, so it is important to take the right amount of antioxidant micronutrients like vitamin C and vitamin E as well as anti-inflammatory macronutrients such as omega-3 polyunsaturated fatty acids to protect the brain from ageing (Whalley et. al, 2004). This is a devastating disease that affects most people over the age of fifty. Recently, there have been many studies done to figure out what causes this disease, if there is anything that can cure it, and how to prevent the disease. Seneff, Wainwright, and Mascitelli, believe Alzheimer’s develops with consuming too many carbohydrates, especially fructose and having a deficiency in cholesterol and dietary fats as well (2010). Whalley, Starr, and Deary have seen that poor diet, poverty, and failing health are links to developing Alzheimer’s Disease (2004). Furthermore, seeing increase in plasma homocysteine concentration increases risk of Dementia, which can result from an inadequate intake of vitamin B12/folate (Walley et. al, 2004). Additionally, Gray supports Walley’s findings and even believes having an adequate intake of vitamin B12/folate will have a positive effect on the overall health

In 2007 geneticists at National Institute of Aging reports that a genetic risk factor called SORL1 was found in the development of Alzheimer’s (National Institute of Aging, 2008). According to Mattson (2004) mutations in PS1 and PS2 are believed to cause Alzheimer’s by increasing production of the neurotoxin (substance causing damage to nerves) forms of AB (antibody). Along with individuals that inherit E4 isoform (protein) are at increased risk of developing Alzheimer’s.

Alzheimer’s disease is a prominent brain disease that effects a massive amount of individuals in the United States. Alzheimer’s disease (AD) is the sixth leading cause of death in the United States, accounting for 60-80% of dementia cases, with no chance of being cured, prevented or decelerating over time (Alzheimer’s Association, 2014). AD is the most well-known form of dementia, causing complications in brain function in the areas of memory, thinking, and behavior (Alzheimer’s Association, 2014). In an effort to gain a deeper understanding of Alzheimer’s disease, researchers create new knowledge about the disease, which is then distributed to the public. The goal in this information disbursement is to find new and inventive ways to treat AD, prevent AD from progressing at such a rapid pace, and aid in the quality of life in those diagnosed with AD as well as caregivers and medical professionals providing treatment to individuals’ with AD.

risk factors include advancing age, a family history of Alzheimer disease,head trauma and damage to the cardiovascular system.

Scientists believed in 1995 that there was a genetic influence in over half the cases of Alzheimer's disease. The gene scientists are giving the most consideration to apolipoprotein E gene (ApoE) as the main gene involved in the development of Alzheimer's disease. Everyone has this gene; if they did not, they would not be alive. ApoE carries a person's cholesterol through their blood. The effect that this gene has in terms of the brain is not totally understood. Scientists have found that

A brain deteriorates, slowly being engulfed by a mysterious disease. The neurons being cut off and destroyed by two abnormal structures. First memory is affected gradually getting worse. Then one is unable to think properly, reason, and lacks of self control. Gaps are formed in the brain 's ventricles, due to the amount of dead tissue. In the end, it will lead to death. All of this may sound like something from a science fiction movie but infact its very real. These are all known possible symptoms of a common disease that affects about millions of Americans. It is known as Alzheimer 's disease (AD), and I plan on explaining it a bit more in this paper. First I will explain the disease and list some facts about it,then I will talk about some commonly asked questions about it.

As Alzheimer’s disease progresses into the mild stage, memory loss becomes worse and changes in other cognitive abilities are evident. These problems include: getting lost, trouble handling money and

Imagine living a wonderful life, yet once someone reaches their golden years, they cannot remember their past. That is the reality of living with Alzheimer’s disease. This disease is commonly found in the elderly. This explains why people assume older people have a bad memory. Alzheimer’s does not occur in a short period of time, it typically takes months to develop. It involves gradual memory loss due to two specific protein fragments that spread to different parts of the brain killing brain cells as they go. As mentioned in the article Alzheimer’s Disease Fact Sheet (2015), Dr. Alois Alzheimer first discovered the disease by noticing something different in a woman’s brain after her death in 1906. Before her death, the woman was reported to have damaged thought processes, vocal trouble, and odd actions, so Dr. Alois decided to examine her brain where he discovered some unusual clusters of plaques and tangles (Alzheimer’s Disease Fact Sheet, 2015). The plaques and tangles initiate in the brain where memories are first formed. Over the years these two protein fragments slowly sabotage the hippocampus making memories harder to remember and develop. People who do not have the disease usually take simple memories from a few days ago for granted. On the other hand, simple memories vanish with patients who have Alzheimer’s. Some of the main characteristics of Alzheimer’s are the plaques and tangles in the brain that not only kill brain cells, but are the reason for failure of

Alzheimer 's disease, or senile dementia, is a form of dementia that affects memory, thinking, and behavior. Brain cells and their connections are killed, and this is what causes people 's brain functions to fail. Scientist have yet to know what causes Alzheimer 's, but have discovered that age, family history, and genes contribute to developing the disease. Symptoms experienced by people with Alzheimer 's are poor judgement, poor decision making, inability to manage a budget, losing track of the date or season, difficulty having a conversation, misplacing things, and being unable to retrace steps to find them. According to National Geographic, symptoms experienced in animals include, “acting disoriented, walking in circles, or staring into corners or at the wall.” So far, not a lot of research has been done on animal dementia. Currently, there is no cure for Alzheimer 's, but there are treatments to help with some brain functions such as cholinesterase inhibitors and memantine to help treat symptoms like loss of memory, confusion, and problems with thinking and reasoning. Certain genes passed down from your parents contribute to a higher or definite chance of developing the disease. Currently, neuroscientists--scientists that study diseases in the brain and nervous system--are committed to creating clinical trials to find a cure for Alzheimer’s. There are hundreds of various clinical trials that have been created to help combat or even cure Alzheimer 's disease.

The Journal of the American Medical Association reports the latest break through in the study of gene causing Alzheimer’s has pointed to two genes, chromosomes 2 and 19 that cause the disease (7). The article also points out another gene, A polipoprotein E-e4, is also linked to Alzheimer’s disease. According to the Journal of Alzheimer’s disease, Jose Vina and Ana Lloret writes that women are at higher risk of Alzheimer’s due

According to most research, scientists, doctors and psychologists say that the causes of the brain damages are genetic factors, nutritional disorders, toxic exposure and radiation factors. In genetic factors, it is studied that Alzheimer’s disease can be caused due to hereditary. This is most commonly seen on patients who suffer the disease before the age of 50. In nutritional factors, scientists project some vitamin deficiencies can lead to Alzheimer disease.