In the United States there are approximately 5.4 million people living with Alzheimer’s. Every sixty-nine seconds a person is diagnosed. This is an ongoing issue, and unless something is done, sixteen million people will be affected by 2050 (Latest).
Alzheimer disease (AD) is the most common cause of dementia in the elderly, accounting for 65–70% of all cases (Jellinger, Janetzky, Attems, & Kienzl, 2008). The other dementias are of the Parkinson 's group, the fronto-temporal group and the vascular group. The total worldwide yearly costs for the treatment and care of patients suffering from dementia are estimated to be around 250 billion US dollars. The lifetime risk for AD between the ages of 65 and 100 is 33% for men and 45% for women with an annual increase of 1–2% in the seventh decade to almost 60% in the 10th decade with doubling every 5 years (Jellinger et al., 2008). AD is incurable, and thus represents a major public health problem. AD represents a challenge to humanity due to its relatively recent discovery, progressive nature of the illness, and complex diagnosis.
Alzheimer’s Disease is a disease of the future. With the growing aged population, this disease, which affects primarily the elderly, will become of increasing relevance to the medical profession. Also, the high frequency of Alzheimer’s, and the high cost in labor, money, and material of caring for its victims shall put considerable burden on the society as a whole. Here, however, these issues are not going to be debated. Instead the pathology of Alzheimer’s will be reviewed to the extent it is known today.
The disease called Alzheimer’s is the fourth leading cause of death in the United States (Weiner, 1987). It is estimated that the elderly population will double between now and 2030. During this period, the number of elderly will grow by an average of 2.8% annually (U.S. Census Bureau, 2001). By 2050, the number of people with Alzheimer’s is estimated to range from 11.3 million to 16 million (Alzheimer’s Association, 2005). These startling numbers should prompt an examination into one of the leading causes of death among this group of people. Understanding what Alzheimer’s is and the known causes of the disease are a good starting point. For those who have aging family members, knowing the risk factors and warning
Researchers believe that Alzheimer’s is more prominent in women than it is in men. Everyday Health says that in the year of 2011 the Alzheimer’s Association reported that “3.4 million of the 5.4 million Americans living with Alzheimer’s are female” (Everyday Health). Gender is another big risk factor in developing Alzheimer’s. When develop Alzheimer’s, they can be more aggressive with their talking and physical abilities. Women are more emotional. They laugh or cry during spontaneously and can have delusions. Researchers also believe that more women have Alzheimer’s than men because the longevity of women. This also coincides with the fact that old age is a high risk
Alzheimer’s disease is a form of dementia, “a brain disorder that seriously affects a person’s ability to carry out daily activities (Shenk 14)”. Alzheimer’s is a progressive and irreversible brain disorder that slowly destroys a person’s memory and ability to learn, make judgments, communicate, and accomplish daily activities. As Alzheimer’s progresses, individuals may also experience changes in personality and behavior, such as anxiety, suspiciousness or aggravation, as well as illusions or hallucinations.
Alzheimer’s disease is one of the most devastating diseases affecting approximately 5.3 million people in the U.S. (Alzheimer’s Association, 2015; Caminiti, 2015; Hammer, 2016). It is not exclusively a disease of old age as over 200,000 are diagnosed under the age of 65. Other startling facts are that a majority of afflicted by Alzheimer’s are women and the rates of diagnosis are increasing substantially (Alzheimer’s association, 2015). Alzheimer’s is a complicated disease that robs a person of their memory and eventually their bodily functions, rendering the person unable to care for him or herself. Furthermore, Alzheimer’s is fatal with no cure or prevention known to this date. There has been a 71 percent increase in Alzheimer’s deaths compared to other major deadly diseases during the first 13 years of this century.
Alzheimer’s disease (AD) is a severe, incurable form of dementia that causes impairment and cognitive deficits such as language, speech, memory and basic motor skills (Buckley, 2011). Currently in the United States, there are 5.2 million individuals living with AD (Alzheimer’s Association, 2013). AD is a deterioration of one’s cognitive functions that prevents the ability for daily function and unfortunately has no known cure or preventative methods (Buckley, 2011).The main deficit that AD has on the brain is the deterioration of different areas of the brain. Not only does a physical toll contribute to patients with AD, but there is also a social stigma that impedes on the normal daily function of life. In this literature review, I will
Alzheimer’s disease (AD) is a progressive and fatal form of dementia, frequently seen in the elderly altering their cognition, thought process and behavior. AD is reported in about half of patients that have a dementia diagnosis; one study states that about 10.3% of the population over 65 years is affected by dementia with an increase to almost 50% over the age of 85. (Beattie, 2002) Alzheimer’s disease is not a normal part of the aging process in humans, but rather found in a group of diseases that affect the brain leading to a decline in mental and physical control. AD when diagnosed has a very slow and gradual course, initially affecting the individual’s short term memory. (Beattie, 2002)
Dementia is one of the age-related disorders which commonly affect the aging elderly population (65 and over). In 2010, the approximate number of people who had dementia was 35.6 million and it is estimated to double every twenty years, to 65.7 million in 2030 and 115.4 million in 2050 respectively. The incidence of dementia every year is 7.7 million which equals to one new case every four seconds (World Health Organization [WHO], 2012). In 2011, the Canadian baby boom generation initially began to turn 65 and became part of the elderly population which significantly impacted the fertility rates (Rockwood & Keren, 2010). In Canada, the elderly population accounts for approximately 13% of the population and one in eleven has dementia (Stein-Parbury & Eliopoulos, 2014). The researchers have estimated that by 2036, it will account for 25% of the population and 28% by 2061 (Bartfay, Bartfay & Gorey, 2013). There are many forms of dementia that an individual can acquire. Alzheimer’s disease is one of the common forms of dementia in the elderly population (National Institutes of Health, 2013). Currently, approximately five million Americans have Alzheimer’s disease (WHO, 2012) from which two thirds account for women (Alzheimer’s Association, 2014). The reason behind more women having Alzheimer’s disease is merely due to the fact that women have higher life expectancy and old age contributes to higher risk for acquiring Alzheimer’s disease. It is apparent that Alzheimer’s disease
Alzheimer’s Disease (AD) has been implicated with two major pathologies, the accumulation of amyloid-B and tau phosphorylation (_). These pathologies have long been implicated with the gene Alipoprotein E (ApoE) which continually showed a dosage-dependent effect on amyloid-B clearance (_). Many studies have shown correlated linkage between ApoE and tau as well as their possible interactions (_). Tau phosphorylation has continually been found among many AD patients suffering with and without amyloid-B deposition (_). However, it is still unclear whether ApoE affects tau pathology separately from amyloid-B. Shi et al. aimed to conduct an experiment to show the direct association of ApoE to taupathy while eliminating the
Alzheimer’s disease is ten leading cause of death in women ages 65-74, the five leading cause of death in women ages 75-84, and the four leading cause of death in women ages 85 and older. The rate of Alzheimer's disease with women exceeded men because the women are living longer than men and the different life of women's would raise the incidence of this disease. Also, genetic variation and biological all affects aging of women. The prevention methods of Alzheimer’s diseases are first, lifestyle people who engage in intellectual activates such as reading, playing board games, completing crossword puzzles, and playing musical instruments all this activates reduced risk for Alzheimer’s disease. Second, diet people who eat a healthy and Mediterranean
It is the sixth leading cause of death in the United States, and is the third leading cause of death for Americans over the age of sixty-five. Almost two thirds of all Alzheimer’s patients are women, and though it seems to be much more common in females than in males, no one has discovered why. Those who are diagnosed with Alzheimer’s experience an array of troubling symptoms. It usually begins with the person forgetting their short term memory. Because Alzheimer’s begins in the hippocampus – the learning part of the brain- they may have trouble remembering names when they are introduced to new people. In the second stage of Alzheimer’s disease, patients can expect to be disoriented at times, have sudden mood and behavior changes, and often develop suspicions about their family, friends, or caregivers. During the end of this stage, they may also experience hallucinations, delusions, and have extreme paranoia. During the third and final stage of Alzheimer’s, patients have difficulty speaking, walking, and swallowing. In this final stage, the brain shrinks to about one-fourth the size of a normal brain, and the person will most likely pass away. Those who have been diagnosed with Alzheimer’s disease are expected to live only about eight years after their diagnosis, due to its progressive nature and worsening over
Alzheimer’s disease is a neurodegenerative disorder, meaning it attacks the neurons within the brain. Neurons are the areas of the brain that allow for chemical messages, or neurotransmitters, to be transmitted. These neurons are necessary for connections with other nerve cells, and without them, the neuronS ultimately die. Alzheimer’s is a form of, and the most common cause of, dementia, or loss of intellectual capacity and personality. ("Dementia.") Alzheimer’s disease, or AD, is not a normal part of aging, although risk of developing the illness increases with age. The onset behavior of the disease normally doesn’t appear until age sixty and older. Though symptoms that appear before age sixty have occurred, it is less common and tends