“You fat moron,” “You aren’t good for diddly” (Arp 94). Being told these words over and over again, a person eventually becomes discouraged and insecure. In Tobias Wolff’s story, “Hunters in the Snow,” main character, Tub is emotionally abused throughout the story. Tub’s two friends, Frank and Kenny haggle him about his personal appearance and sensitivity as he struggles throughout the story. Frustration and insecurities lead him to the conflict that he always tries to avoid. The emotional abuse
gene amplification and telomere shortening occur frequently. 37 CDKN2A encodes for the inhibitor of cyclin-dependent kinase 4 (INK4A). 95 % of tumors have inactivation of CDKN2A. 19 This results in loss of p16 protein which is a protein regulating G1-S transition in the cell cycle. TP53 is allowing cells to pass by DNA damage control checkpoints and apoptotic signals which leave the cells genome instable. 19 TP53 inactivation is seen in 50-75 % of tumors. The deletion of SMAD4 gene is present at 55
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