An Overview Of Multiple Sclerosis

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An Overview of Multiple Sclerosis: the Disease, the Challenges, the Symptoms, and the Treatments
Meiying Li

Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system. The characteristics of MS are demyelination and axonal loss. The etiology of MS is unknown, and there is no cure. Diagnosis to confirm MS has been complicated but is now improved with acceptance of the revised 2010 McDonald Criteria. The disease produces numerous physical and mental symptoms which require both
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These lesions, consist mostly of dead nerve cells, whose axons have lost their myelin sheaths that normally protect them and permit the conduction of nerve impulse.
(Joy JE, Johnston RB, 2001) This immune system attack of the body 's own myelin sheath is why MS appears to be an autoimmune disease. MS is a chronic degenerative disease that usually begins in young adulthood and destroys muscular control. Most people will live with MS for many years after their diagnosis. MS reduces life expectancy by only about ten-fifteen years, and about half of the patients survive thirty years or more from onset. (Joy JE, Johnston RB, 2001) Approximately eight-five percent of MS patients begin with relapsing-remitting disease, as in optic neuritis, or several separate systems at the same time, for example, combined motor and sensory problems. Attacks involving single neural systems are somewhat more common in the first MS relapse. Most patients experience their second attack within two to three years of the first, but five percent of patients remain free of relapses for fifteen years or more. In most cases,
AN OVERVIEW OF MULTIPLE SCLEROSIS 4 there is substantial recovery from the first relapse; only four percent of patients show no improvement. (Joy JE,
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