Essay on An Overview of Multiple Sclerosis

2251 Words10 Pages
An overview of the chronic inflammatory demyelinating disease: Multiple sclerosis BACKGROUND The central nervous system (CNS) comprises grey matter, which contains neuron cell bodies and white matter, which contains the nerve axons. Most of the nerve axons are concentrically wrapped around by lipid-rich biological membrane, known as the myelin sheath. In the CNS, myelin is produced by oligodendrocyte. a type of glial cell. (Pfeiffer et al., 1993). These electrical insulating, multilamellar membranes significantly increase the electrical resistance, in which to prevent leakage of electrical currents from the axons, as well as decrease electrical capacitance to reduce the ability of the axons to store electrical energy (Shivane &…show more content…
An overview of the chronic inflammatory demyelinating disease: Multiple sclerosis BACKGROUND The central nervous system (CNS) comprises grey matter, which contains neuron cell bodies and white matter, which contains the nerve axons. Most of the nerve axons are concentrically wrapped around by lipid-rich biological membrane, known as the myelin sheath. In the CNS, myelin is produced by oligodendrocyte. a type of glial cell. (Pfeiffer et al., 1993). These electrical insulating, multilamellar membranes significantly increase the electrical resistance, in which to prevent leakage of electrical currents from the axons, as well as decrease electrical capacitance to reduce the ability of the axons to store electrical energy (Shivane & Chakrabarty, 2007). Therefore, myelin sheath enables the fast-speed saltatory conduction of the nerve impulses. Demyelination is a group of diseases that characterized by the destruction of the normal myelin sheath, with relative preservation of the axons. Myelin sheath degeneration might be resulted from the disease that directly damage the myelin sheath, or the disease that damage the oligodendrocytes (Love, 2006). Eventually, demyelination leads to the impairment of the normal conduction of the electrical impulses in the affected nerves. MULTIPLE SCLEROSIS Multiple sclerosis (MS) is the most common inflammatory demyelinating disease in the CNS. It is a chronic neurological disease that normally affects young people and it is one of the

More about Essay on An Overview of Multiple Sclerosis

Open Document