Analysis of Aspirin

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1. Aim To determine the percentage of aspirin in different commercial preparations and to find which is the best value for money 2. Hypothesis The greater the percentage of acetylsalicylic acid (ASA) in the tablet, more powerful and efficient the aspirin would be due to the way aspirin works in human’s body. Aspirin is often used to alleviate the pain, and the sensation of pain is mainly attributed to a chemical substance called prostaglandins, which is responsible to send a strong signal to the brain to remind the damage of the body. Working cells in the damaged area produce prostaglandins using an enzyme called cyclooxygenase 2 (COX-2), and aspirin works by disturbing COX-2 functions. By doing so prostaglandins are no more…show more content…
Bayer had the highest percentage purity of 89.2%, which is also the closest to the actual percentage purity, and moreover the data was precise(89.1% and 89.2%). However, the percentage error (18.49%) is way greater than the percentage uncertainty (5.4%), and the value does not fall within the range 99.5% ± 5.4%. Since random error is estimated by the uncertainty and it is smaller than the percentage error, systematic errors are at work making the measured data inaccurate. The similar results were noted for two other brands, Bamyl and Baijunyu, and especially Baijunyu showed the highest percentage error of all (49.74%), which makes it highly doubtful about its accuracy in the experiment. All three brands weren’t able to fall within the range 99.5% ± 5.4%, and as the percentage error for all three brands is greater than its percentage uncertainty, it is considered that systematic error is the biggest reason for inaccuracy in the experiment. However, in spite of the failure in calculating accurate percentage purity that falls in the region 99.5% ± 5.4%, it was accurate enough to find out the most cost-efficient brand among three. The table below shows the comparison between the price of aspirin per gram and the percentage purity. Brand | Price per gram (RMB/g) | Percentage purity (%) | Bayer | 6.67 | 89.2 | Bamyl | 1.2 | 81.1 | Baijunyu | 8 | 50 | As shown in the table, the
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