Andrew Fleming 's Discovery Of Penicillin Essay

The Immortal Life of Henrietta Lacks by Rebecca Skloot explores the historically racist treatment of black patients by doctors. Henrietta was alienated by her doctors and was not educated about her disease and the things they were doing to her body. Elsie, Henrietta’s daughter, was wrongfully experimented on by the doctors that were supposed to be taking care of her in the mental institution. African Americans as a whole race have always been ostracized by their doctors and scientists since their history in America began.

The experiment first began in 1932, in a small county within the Macon County of Alabama area. In this are rate of syphilis was up by 35%. Interestingly, the setting of the study was conducted at the Tuskegee Institute, which we know now to be Tuskegee University. The study conducted of 399 men, 201 out of the 399 were used as the control group. The control group contained of those who actually didn’t have the diseases. The study also targeted those who were poor and illiterate. A lot of those patients had the slightest clue to which they were being tested for, only being told they had “bad blood”. The doctors participating in the study thought it would be vital; to not inform

STD’s have been around for a long time, dating back to 1550 B.C. During this time the first recorded form of an STD was found. They were reported to be found in Europe. Gonorrhea and Syphilis are recorded to be the two most common diseases in Europe. Some men on Christopher Columbus’s voyage brought back syphilis with them. Syphilis causes progressive destruction of the brain and spinal cord, leading to mental dysfunction and hallucinations, speech problems and general paresis (G. Burg). The common knowledge of STD’s have been around but have not been able to be treated up until around the late 1700s.

This essay examines the Tuskegee Syphilis Study, wherein for 40 years (1932-1972) hundreds of black men suffering from advanced syphilis were studied but not treated. The 40-year study was controversial for reasons related to ethical standards; primarily because researchers knowingly failed to treat patients appropriately after the 1940s validation of penicillin as an effective cure for the disease they were studying. To explore the role of the racism in the controversial study, this essay analyzes the article written by Allan M. Brandt.

The Tuskegee Syphilis experiment (The official name was Tuskegee Study of Untreated Syphilis in the Negro Male) began in the 1930’s. It was an experiment on African Americans to study syphilis and how it affected the body and killed its victims done by Tuskegee Institute U.S. Public Health Service researchers. The initial purpose of the Syphilis study “was to record the natural history of syphilis in Blacks” (Tuskegee University, “About the USPHS Syphilis Study,” par. 2). The study was necessary because syphilis was a disease that didn’t yet have an official cure (when the study began in the 30’s). There were 600 men in all; 399 had syphilis and 201 served as a control group for the experiment. The

The men were never given adequate treatment for their disease. Even when penicillin became the drug of choice for syphilis in 1947

(Tuskegee University) Out of the 600 African American men, the United States Public Health Service refused to treat 399 of the men who were diagnosed with syphilis with late stage. From these men, “perhaps more than 100 had died directly from advanced syphilitics lessons.” (Brandt) From the Tuskegee University, it’s stated that the doctors and researches used the excuse of bad blood in order to get men participating.

The men had to consequently suffer and deal with pus filled sores covering their body, including their mouths, just so the scientists could study the lasting effects of untreated syphilis. Suffering from syphilis was not what the men signed up for, and to them, there seemed to be no way out of the suffering. Even research by the Center for Disease Control (CDC), “Found nothing to show that subjects were ever given the choice of quitting the study.” Even though the men most likely felt trapped, they still had to go on with their everyday lives, which included their healthy significant others.

The discovery of penicillin was one of the most important discoveries in the 1900s and marks a turning point in human history. Penicillin was one of the world’s first antibiotics which eventually evolved into modern antibiotics that are used today; it has often been described as a miracle drug. The discovery of penicillin meant that doctors finally could completely cure their patients of deadly diseases. After World War I, many soldiers died from infected wounds because the antiseptics used, killed the patients’ immunological defences more than they killed the invading bacteria. Penicillin kills bacteria by destroying the cell wall of the microorganism causing the cell to burst; it was very effective in clearing bacteria without harming the

by Dr. Alexander Fleming. As test continued, Fleming began to realize that he was on the verge of a great discovery. However, he still did not know the identity of the fungus, and had little knowledge of fungi. His crude extracts could be diluted 1,000 times and still be effective in killing bacteria. After years of working on penicillin and going nowhere, many of his co-workers grew tired of hearing about it. The first real test for penicillin came when a 48-year-old police officer nicked himself shaving. After a time, Alexander's face became infected and he developed a temperature. When he was rushed to the hospital, the doctors believed that he had only hours

The study took place in Macon County, Alabama where a large number of African Americans were infected with syphilis. Although the study was aimed at discovering whether blacks react to syphilis in the same way as whites, and determine how long a human being can live with untreated syphilis. Due to the African Americans having lack of education, they suffered tremendously at the hands of doctors from the US Public Health Service. When the study was initiated there were no proven treatments for the disease. So the researchers told African American patients they were being treated for “bad blood.” The treatments for syphilis in the early 1930’s offered more potential harm than benefit for the patient so little harm was done by not treating the men in the study.

None of the men knew that the “bad blood” which coursed through their veins was contagious. None understood how the disease was transmitted; no one explained to them that congenital syphilis was passed on from female to fetus. It was an experiment based on deception, a characteristic that it retained for the next forty years. Through a historical analysis of the experiment several questions arise, particularly the issues of the men’s participation in the experiment and the black professionals who witnessed the study. Why did these Black men take part in this study? Why did the Black health professionals not challenge the study? The answers to these questions are interconnected and lies captive in a term Jones calls racial medicine (Jones 15).

Syphilis is one of the oldest sexually transmitted diseases in the world. The first recording of Syphilis was in Europe in 1495, but there is believed to be earlier cases that weren’t recognized. “The transatlantic origin of syphilis is still controversial as there was evidence of an endemic syphilis in Asia Minor before 1492” (JG, 1990) . There has not been a definitive origin for this disease and there were several different hypotheses on how it came to the United States. There have been 2 main theories proposed. The first was the New World or Columbian theory and the Old World or pre-Columbian theory. The first theory holds that the syphilis endemic started in the part of the world now known as Haiti and was then acquired and carried to Europe by Columbus in the 1400s. The second theory, pre-Columbian theory implies that syphilis began in central Africa and was brought to Europe prior to the voyage by Columbus. Recent studies have shown genetic differences between these organisms. Regardless of where the beginning of syphilis started, by 1495 a widespread syphilis epidemic had spread throughout Europe, and then on to India in 1498 and China in 1505. Since its discovery in Europe there have been many speculations that many famous ranging from political figures, musicians and some literary greats may have had syphilis. Some of those were Adolf Hitler, Ivan the Terrible, Henry VIII, Shakespeare, Napoleon, Abraham Lincoln, Lenin (Vladimir Ulyanov), Friedrich Nietzsche,

What is syphilis? The aim of this essay is to find out if syphilis affects a particular gender or age group, and if so, how it is transmitted? Many people are unaware of this disease as the occurrence reduced considerably after penicillin became available. However, this disease is not completely extinct. “The past decade has seen a rise in new cases of the almost forgotten historic disease syphilis, particularly in certain risk groups” (Wohrl and Geusau, 2007). Syphilis is a sexually transmitted disease that is caused by a bacterium Treponema palladium. When syphilis is passed on sexually it is called venereal syphilis (Wohrl and Geusau, 2007). This disease can also be transmitted to an unborn child via the mother; this is called

How would it feel to save a life? How would it feel to save a few? Imagine saving millions. Alexander Fleming knew that all too well. Although his name should sound familiar, most people know very little about him, if anything at all. Just as discoveries can lead to inventions, inventions can sometimes lead to discoveries. In 1928, Alexander Fleming discovered penicillin. Prior to his discovery, patients with infections or trivial injuries often died. A doctor would have to watch, wait, and hope that a patient's immune system would be strong enough to fight and heal. Throughout history, inventions and discoveries have been made to change or save lives, but most are not discovered by accident.