Anemia And Arthralgia Case Study

A woman comes into the hospital complaining of extreme fatigue that does not go away with rest, she has a fever over 100 degrees Fahrenheit and she has some skin sores and rashes, almost in a butterfly-shaped pattern across her cheeks and nose. After blood and urine tests, the signs and symptoms and physical examination findings leads to the diagnosis of lupus.

Do you know that there is currently three types of lupus? Discoid lupus, systemic lupus erythematosus, and lupus like a disorder called destroyer made lupus. Discoid lupus remains limited to our skin and be present in the form of a rash that appears on your face, neck or scalp. The appearance of the rash may possibly be more outward on areas of the skin exposed to electromagnetic lighting. While close by stand many forms of lupus epidemics the most communal is elevated, incrusted and rosy nevertheless not irritated. SLE remains commonly extra plain than discoid lupus. Do you know Discoid lupus is a form of lupus that is be able to cause inflammation in your organs?On behalf of nearly half of our society, this can be to

A 79-year-old female present with her daughter for ongoing fatigue also noted to have lost 5 pounds over past 6 months. No night sweats or fevers. Pertinent past medical history includes severe, generalized osteoarthritis, hypertension, type 2 diabetes mellitus and depression. She is taking the following medications: acetaminophen 650mg every eight hours, Lyrica 75 mg twice daily; alendronate 70 mg once weekly, valsartan 320 mg once daily, fluoxetine 40mg once daily and insulin glargine 20 units once daily. Your exam reveals slight pale conjunctivae, a 2/6 systolic ejection murmur and generalized arthritic joints in her extremities. A point of care test results in a hemoglobin of 10.2 g/dL. Complete blood cell count is done; results

Discoid Lupus Erythematosus (DLE)is an autoimmune disease that affects the skin, DLE causes skin rashes and lesions on the scalp, internal ear, nose, and cheeks, unfortunately, hair loss and skin pigmentation occur with this disease. This rare disorder seems to be more common in women (between the ages of 20-40) than in men and is hereditary. Ten to twenty percent of people (around 200,000 US population) who have DLE will develop its more severe cousin ASLE (acquire systemic lupus erythematosus) which can be life threatening.

Lupus is still somewhat of a mystery to physicians and scientists today. Historically, the disease has stumped medical professionals. The first known discovery and identification of lupus, specifically systemic lupus erythematosus, was made by Hippocrates, a Greek physician, around the time of 400 BC. The disease became more well known after many years, and by the late 1700’s, two British dermatologists Robert Willan and Thomas Bateman had started to “use the term “lupus” to describe a destructive skin disease preferentially affecting the face and the nose” (Konya, 2016). Then the modern era of lupus began in 1923, when one doctor discovered four cases with similar symptoms. The physical details of the disease became more specific and by 1967, doctors were able to find a way to test for the antibodies that were associated with the disease. In the past, people thought the symptoms of lupus resembled a wolf bite, and some theorized the skin swelling and color changing was caused by werewolves. This theory has since been proven wrong, clearly. Because of this theory though, some people with the disease may have been wrongfully mistreated in the past. Today, lupus is a disease that allows people to receive help from the government under disability status. People with Lupus are not mistreated and in most places, are even protected by disability discrimination acts.

Systemic Lupus Erythematosus – otherwise known as lupus – is an inflammatory autoimmune condition and typically affects women of reproductive age and causes joint pain. Other manifestations of the disease include fatigue, rash, dry eyes/mouth, inflammation in other parts of the body, and blood cell abnormalities. One of the most worrisome complications of lupus is kidney disease, which is a common cause of dialysis dependence in young women. Lupus is also associated with an increased risk of heart attack and stroke.

Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple tissues and systems and with significant variable clinical features and organ involvement (Cava, 2010). It is characterized by a chronic, relapsing, inflammatory and often febrile multisystemic disorder of connective tissue with wide spectrum of involvement of skin, joints, kidneys and serosal membranes. The exact etiology is noknown, but it represents failure of the regulatory mechanisms of immune system in which body 's own defenses are turned against themselves (Edworthy, 2005##########).

“The most common symptoms of lupus include painful or swollen joints (arthritis), unexplained fever, and extreme fatigue. Because many people with lupus are sensitive to sunlight (called photosensitivity), skin rashes often first develop or worsen after sun exposure”(National Institutes of Health). “Chest pain, hair loss, anemia (a decrease in red blood cells), mouth ulcers, and pale or purple fingers and toes from cold and stress are also other symptoms of SLE.” “New symptoms may continue to appear years after the initial diagnosis, and different symptoms can occur at different times” (National Institutes of

There are five main symptoms that most patients with lupus nephritis present (The Nat’l Kidney Foundation). Hematuria and proteinuria are usually the initial symptoms and involves the glomeruli leaking protein and/or blood into the urine. As the kidney disease progresses, edema can develop due to extra fluid that the kidneys cannot remove. This in turn, causes weight gain although you’re more likely losing weight with this disease – that is, fat. High blood pressure is also developed due to heart and blood vessel problems. Kidney symptoms usually develop during or shortly after lupus symptoms. The lupus symptoms include joint pain, swelling, muscle aches, fevers with no known cause, and red rashes on the face. The initial diagnosis of lupus is usually simple, but in most cases other diseases are suspected first. The full diagnosis can be postponed due to its ability to mimic other diseases and conditions. Series of tests are completed in order to determine how far the disease has progressed. Urine and blood tests are performed to find out if there are abnormal levels in the blood and if anything abnormal is present in the urine. Blood tests for lupus nephritis generally check for protein and cholesterol levels; the glomerular filtration rate (GFR); and antiphospholipid antibodies and anti-nuclear antibodies (ANA). Presence of ANAs, along with most

The Report dated 06/19/2017, indicated that the claimant had severe fatigue and chronic pain secondary to systemic lupus erythematosus and hemochromatosis. He was deemed incapacitated from 05/01/2017 through 07/31/2017. Monthly appointment for blood letting was advised. A referral to Hematology and Oncology was made.

Skin : systemic lupus erythematosus typically manifests as a skin redness of the face in the form of butterfly (erythema). This intensifies erythema with exposure to UV radiation (sunlight). SLE can also cause visible rashes on other parts of the body. Those affected generally have a high photosensitivity. The disease presents with other symptoms such as irreversible hair loss ( alopecia areata ), inflammation of the vessels small skin ( vasculitis ) with minor bleeding around the nails or inflammation of the oral mucosa.

Verma S, Verma G, Shanker V, Tegta G, Sharma A, Pandey M. Facial lupus vulgaris of bilateral

: This is a 39 y/o woman who presents to the clinic to establish care. She reports a medical history of “skin lupus.” She states this was diagnosed in 9/2014 after a skin biopsy at her dermatologist office. She was started by her previous rheumatologist on 200 mg Plaquenil daily, in October 2014. However, in November 2015, she decided by herself to decrease the Plaquenil dose to 100mg daily, due to nausea. Her rash was well controlled until February this year. She reports that in February she developed a rash on her bilateral upper arms that didn’t go away for about 2 months. Her main concerns at his time are a new rash, body aches throughout the day, and fatigue “all the time.” The new rash is affecting only her lower back, developed 2 days

Systemic Lupus Erythematosus (SLE) has its own specific sign and symptoms, which each person with this disease may has slightly different symptoms which can range from mild to severe and may come and go over time. The common symptoms of SLE are painful or swollen joints and muscle pain, unexplained fever, red rashes (butterfly rashes) which usually on the face, chest pain upon deep breathing, unusual loss of hair, pale or purple fingers or toes from cold or stress which also know Raynaud’s phenomenon, sensitivity to the sun causing the skin to become seriously irritated, swelling (edema) in legs or around eyes, mouth ulcers, swollen glands and extreme fatigue. However, SLE’s symptoms mostly include painful joint, unexplained fever and extreme

Systemic Lupus Erythematosus (SLE) is a chronic inflammatory disease that occurs when a person’s immune system attacks your own tissues and organs. SLE is characterized by the presence of autoantibodies directed against nuclear antigens. By definition, SLE is a multi-system disease, and patients can be infected in vastly different ways. SLE is the form of the disease that most people are referring to when they say “lupus.” The word “systemic” means the disease can affect not one, but many parts of the body (Johnson, 1999). SLE can affect every organ in the human body. The most common manifestations are rash, arthritis and fatigue. According to the Mayo Clinic, some complications of SLE are kidney failure, neurological problems, anemia,vasculitis,