2002). Consequently, autoimmune disorders are the results of a breakdown of the body's ability to acknowledge its own cells from foreign cell that causes it to produce an immune response against itself. This, in turn, triggers the body's own defense mechanism to produce antibodies that attack the body's own tissues and cells. (Franz, 2006, Laberge, Davidson, 2007). The immune system’s mission is to act as a defense mechanism against infections. An autoimmune disorder is the result of the body’s immune
Blood Disorders Amanda Swindell HCA/240 August 9, 2015 Dr. Monica Chase Blood Disorders Blood is one of the most essential elements within the body. Blood is made up of plasma, red blood cells, and platelets. Blood is vital to the body functioning correctly, and it is important to understand that there are many types of blood disorders that can cause people to get sick. While there are many different types of blood disorders out there, this paper is going to cover three which are, anemia, sickle
Blood Disorders Elizabeth Martinez HCA/240 December 19, 2010 Melvina Brandau Some blood disorders can be prevented while there are others that are out of a person’s hands and have to live with a blood disorder for a life time. It is essential to know the causes of hereditary disease and know how to treat them. It is also important to know what can be done to “cure” other blood disorders and what preventive measures need to be taken in order to stop history from repeating itself. Iron deficiency
Anemia is a condition that develops when your blood lacks enough healthy red blood cells. These cells are the main transporters of oxygen to organs. If red blood cells are also deficient in hemoglobin, then your body isn't getting enough oxygen. For this reason, doctors sometimes describe someone with anemia as having a low blood count. A person who has anemia is called anemic. It can reduce your quality of life and increase your risk of death. Anemia is the most common blood condition in the U.S
Thalassemia is a blood disorder transferred through families. It occurs when the body makes less hemoglobin than needed or an unusual form of hemoglobin. Hemoglobin is the protein in red blood cells that carry oxygen. The disorder makes an excessive amount of destruction of red blood cells. This eventually leads to anemia. There are two main types of thalassemia. The first one is Alpha thalassemia. This occurs when a gene or genes related to the alpha globin protein are missing or mutated. It happens
Immune-Mediated Hemolytic Anemia (IMHA) is one of the most severe autoimmune disorders that kills between 29-77% of dogs each year [1]. The disease is usually found in large and middle aged dogs. IMHA is a pathologic process that results in premature destruction of red blood cells when an immune response directly or indirectly targets red blood cells of all ages[ 2]. IMHA can be caused by various factors, but categorized in two ways. IMHA can be an idiopathic autoimmune event (primary IMHA) or associated
Blood Disorders Natasha Hurndon HCA/240 Janet Jowitt October 13, 2014 The blood in the body is made up of many different components. The components of the blood include red blood cells, plasma, and platelets, each having a specific function. In this paper I will explain the difference between the three and the specific function they carry out within the human body, as well as how the relate to the scenarios in this week’s assignment. Red blood cells are the most needed of the three
Megaloblastic anemia due to dihydrofolate reductase (DHFR) deficiency 1. Abstract Studies have shown that folate deficiency megaloblastic anemia is associated with dihydrofolate reductase (DHFR) deficiency due to mutations in the DHFR gene. In order for tetrahydrofolate (THR) to be able to participate in the de novo synthesis of DNA building blocks, it needs to be regenerated from dihydrofolate (DHR). Regeneration of THR requires DHR to be reduced by the enzyme DHFR. Hence, a deficiency in DHFR
every cell in the body. Mutations that occur only in an egg or sperm cell, or those that occur just after fertilization, are called new (de novo) mutations. De novo mutations may explain genetic disorders in which an affected child has a mutation in every cell, but has no family history of the disorder. Acquired (or somatic) mutations occur in the DNA of individual cells at some time during a person's life. These changes can be caused by environmental factors such as ultraviolet radiation from the
Sickle-Cell Anemia is an inherited, chronic blood disease in which the body produces abnormally shaped red blood cells. When the blood cells become crescent/sickle shaped, they are unable to deliver adequate amounts of oxygen to other cells. Also, these unusual “sickle” cells block blood pathways to the limbs and organs, limiting the amount of blood flowing throughout the body. It causes pain, organ damage, and anemia (low blood count). Unfortunately, however, when sufferers are born with this disease