Angiotensin Research Paper

The role of diuretics in heart failure is to reduce the fluid retention by diuresis (1). Patient should be monitored closely to prevent over diuresis that will subsequently lead to hypotension and renal impairment. Diuretic used is commonly associated with hypokalemia (1). Thus, additional potassium needs to be given concurrent to diuretic treatment (1). Patient’s daily weight must be recorded and aimed for reduction of body weight >4.5 kg in 5 days after treatment (7). Angiotensin converting enzyme inhibitor (ACE-I) is a first line agent in treating heart failure, especially when there is evidence of reduced in ejection fraction <40% as it improve survival rate of patient (1). Patient needs to be advised regarding side effects of the drug which are, dry cough, hypotension, renal insufficiency, hyperkalemia and angioedema. Antihypertensive agents that can be given in patient with heart failure are beta blocker, ACE-I and aldosterone antagonist. If the blood pressure is persistently high despite treatment with beta blocker, ACE-I and ARB, calcium channel blocker such as amlodipine can be added as this drugs has negative inotropic effect

ACE inhibitors are important and useful in the medication and treatment for KH due to their effectiveness in treating hypertension. ACE inhibitors will help treat KH by slowing the angiotensin converting enzyme (ACE). Angiotensin II is produced by the body that can cause vasoconstriction of the blood vessels. Angiotensin II is made from Angiotensin I by the ACE. If the production of Angiotensin II is slowed by the ACE inhibitor, the blood vessels will be able to dilate, and blood pressure is able to be lowered (Copstead and Banasik). Thus, it is important for KH to stay on the ACE inhibitors due to his blood pressure readings. KH’s blood pressure is 135/96. His systolic blood pressure is in the pre-hypertensive range, however, his diastolic blood pressure is in the hypertensive range and therefore, his blood pressure is hypertensive. Since his blood pressure is high, it is important for KH to remain taking the

Being forgetful, slurred speech, feeling sad or empty, relaxed and calm, loss of interest or pleasure, sleepiness or unusual drowsiness, lack of appetite, clumsiness or unsteadiness, feeling tired, trouble concentrating and less common side effects would be things like cough, dark urine, diarrhea, blurred vision, body aches or pain, shaking or shivering , nausea, seizers and the list goes on.

Lisinopril medication is an angiotensin-converting enzyme (ACE) inhibitor, which treats heart disease by causing vasodilation of the arteries and control extracellular volume (Amador, &

Patients who have congestive heart failure and do not respond to diuretics may benefit from a combination of several types of diuretic medication, each with a different system of action. Another medication for someone that has congestive heart failure can take Beta-blockers. Side effects include fatigue, cold hands, headache, upset stomach, constipation, diarrhea, dizziness, and shortness of breath. Data reported from 17 studies, researchers came to the conclusion that the risk of death from all causes was 31 percent lower in patients with heart failure who were treated with beta-blockers than in those not receiving such medications. Aldosterone blockers is a form of medication one may take to help slow down the rate of congestive heart failure.This medication can sometimes affect kidney function and can also increase potassium levels. Aldosterone blockers are prescribed to individuals who develop heart failure after a heart attack. Studies show that these medications can reduce the risk of hospitalization and death from cardiovascular disease. The last form of medication is BiDil (isosorbide

The potential complications if you do not stay compliant with the regimen are; low potassium which can lead to muscle cramps, weakness and fatigue, constipation, difficulty breathing, or an abnormal heart rhythm; Acute kidney failure

Side Effects: Frequent urge to urinate, headache (continuing), loss of appetite (continuing), mood or mental changes, muscle pain or twitching, nausea or vomiting, nervousness or restlessness, slow breathing, swelling of feet or lower legs, unpleasant taste, unusual tiredness or weakness

Some of the most common side effects include decreased breathing and most of the users that do this drug end up becoming physically dependent. Other side effects can vary from person to person but some of them are having constipation,

Current medications include metformin, simvastatin, hydrochlorothiazide, trazodone, losartan, citalopram, metoprolol, aspirin, isosorbide dinitrate 30 mg, nitrostat, Vitamin,

No more than 2 percent of hypertensive patients can be treated surgically. There are basically four groups of drugs a physician would prescribe a hypertension patient:DiureticsThis is usually the first choice a doctor would prescribe. It helps by increasing the rate you body eliminates urine and salt. However, this can also increase your cholesterol level, make you urinate more frequently, and may cause a loss of potassium.Beta-Adrenergic BlockersThese drugs are usually prescribed if a diuretic does not help bring your blood pressure down, and sometimes are used in combination with diuretics. Beta-adrenergic blockers work by blocking the effects of adrenaline in your body.

This drug is used as an antidepressant. Anxiety, dizziness, blurred vision, dry mouth, diarrhea, and weight gain or loss are common effects of the medications and with aging. But serious effects such as fever; seizures, tremors, chest pain, hepatic necrosis, renal failure, abnormal bleeding, and infection should be cautioned. The dosage of this medication should not be prescribed more than 40 mg daily. Monitoring for mental changes when taking this medication is needed. It should be cautioned to watch for a change in behavior from depression into a mental illness. If this occurs medical attention is needed. Nurses should also assess elderly patients taking diuretics for signs of suggesting syndrome of inappropriate secretion of antidiuretic

The first line choice in patients with heart failure is Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors). ACE inhibitors can help slow progression of heart failure and improve symptoms. ACE inhibitors block the action of a protein (enzyme) that causes blood vessels to narrow. As a result, blood vessels relax and widen. This lowers blood pressure and makes it easier for the heart to pump blood. These medicines also help body release water and sodium, which also helps lower blood pressure. ACE inhibitors relieve heart failure symptoms, such as fluid retention and edema. They may help reduce liver disease and prevent readmission to the hospital. Examples of ACE inhibitors are Captopril, Enalapril, Lisinopril, Quinapril, and Ramipril.

Medications that can cause interactions include anticoagulants, probenecid, bisphosphonates, angiotensin-converting enzyme (ACE) inhibitors, anticoagulants (Warfarin), antiplatelet medicines (Clopidogrel), aspirin, corticosteroids (Prednisone), heparin, other NSAIDs (Ibuprofen), Rivaroxaban, or Selective Serotonin Reuptake Inhibitors (SSRIs) (Fluoxetine) due to the risk of stomach bleeding may be increased. Bisphosphonates (Alendronate), Cyclosporine, Hydantoins (Phenytoin), Lithium, Methotrexate, Quinolones (Ciprofloxacin), Sulfonamides (Sulfamethoxazole), and Sulfonylureas (Glipizide) side effects may be increased by Naproxen. The effectiveness of Angiotensin-converting enzyme (ACE) inhibitors (Enalapril), Beta-blockers (Propranolol), or diuretics (Furosemide, Hydrochlorothiazide) may be decreased by Naproxen (Lexi-Comp,

The purpose of this report is two discuss the Pharmacodynamics, pharmacokinetics, proposed benefits, research method, results of research, and possible-nursing implications of newly approved drugs for the treatment of hypertension. These drugs include Atacand HCT and Diltiazem HCL. All newly approved drugs from the FDA are either new drugs or new formulations of older drugs. The information contained in this report was derived from various web pages and online search engines.

Other side effects include cloudy urine, proteinuria, irregular heartbeats, and chest pain. Angioedema involving the extremities, face, lips, mucous membranes, tongue, glottis or larynx has been seen in patients treated with ACE inhibitors, including captopril (Capoten, 2014). If these effects happen nurses should be ready to administer epinephrine to reduce swelling. Other adverse effect according to Karch (2014) include, “CV: Tachycardia, angina pectoris, heart failure, MI, Raynouds syndrome, hypotension in salt-or volume depleted patients.”