Animal Care And Experimental Procedures

tested on? Animals have been used in research for the past couple of decades and it continues to be a topic of serious debate to this day. Animal testing involves the process of subjecting animals to clinical trials rather than human trials in order to test the effectiveness of certain drugs and products. The debate is whether or not it is morally right or wrong to use animals during experimentation. Many scientists argue that it is necessary to use animal research in saving lives, but animal rights

make certain that the animals are treated in a humane and ethical way, researchers are regulated and monitored by various government agencies. The US Department of Agriculture is responsible for enforcing the Animal Welfare Act and conducts unannounced inspections of research facilities. If the research is a grant recipient, the National Institutes of Health would be responsible for the regulation as well. The American Association for the Accreditation of Laboratory Animal Care (AAALAC) is responsible

Animal Experimentation has a long history for the use of humankind and animals are being used in a large number to study and develop drugs for the diseases that human beings suffer from. “Between 17 million and 22 million animals are estimated to be used annually in the United States in research, education, and testing and about 85 percent of these are rats and mice, and less than 2 percent are cats, dogs, and nonhuman primates (Office of Technology Assessment, 1986)” (National, R. C. S. 1988, p

insulin used daily to treat and manage levels of blood glucose are both the end results of long and costly research. Without research the awareness of vitamin deficiencies, treatments for cancer, organ transplantation, and vaccines for humans and animals would cease to exist. It all begins in the laboratory and the study of pathophysiology which looks at how living organism function and the effects certain disease. Basic research “bench studies” or preclinical research is performed

ts. For the experimental procedures, either a whole animal or its organs and tissues are used. For this purpose animals are euthanized (killed) by established methods. Many times, the animals surviving the clinical testing are euthanized at the end of an experiment to avoid the later pain and distress (Rusche, 2003). In some cases (for example in LD 50 analysis) animals die as a result of the experiment. The pain, distress and death experienced by the animals during scientific experiments have been

Animal testing, because of its links to animal cruelty, causes many people to question whether it should be outlawed. Without animal testing in medical field, medical research would not have the vaccinations in use today that saves lives every minute. Galen, a European physician in 200 AD, used animal experimentation to understand and comprehend the complexity of the human body. Even in today’s time, the human body is a mystery and things happen that physicians cannot explain or understand. Has

health care is not a new idea, the name associated with it, medical tourism, is. Medical tourism is a new global economy in which patients travel to a foreign country to get health care (Stolley and Watson 1). To many people, traveling to another country for health care seems unnecessary and dangerous. However, there are numerous benefits to medical tourism. Medical tourism is all about patients getting the best medical care at the lowest cost. Medical tourism offers patients health care at a lower

requirement under the Animals (Scientific Procedures) Act 1986 as amended in 2012. (ASPA). Before a project licence is granted, the Secretary of State (advised by an inspector) must weigh the likely benefits from the programme of work against the likely harms to the animals involved. They must be satisfied that there are no alternatives to using the animals, and that the procedures will use minimal numbers and cause the least suffering. All breeding, supply or scientific procedure establishments must

In his proposal, Professor King states that “control animals will be subjected to sham surgery.” This is not acceptable. According to the Guidelines for Ethical Conduct in the Care and Use of Nonhuman Animals in Research, “In general, laboratory animals should not be subjected to successive survival surgical procedures, except as required by the nature of the research, the nature of the specific surgery, or for the well-being of the animal.” The sham surgery is not necessary to see if the surgery

Experimental Design and Aortic Stenosis Model All experiments and procedures were performed in accordance with the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of Health and were approved by the Animal Ethics Committee, São Paulo State University (#198). Three- to four-week-old male Wistar rats weighing 90–100 g were anesthetized with a mixture of ketamine (50 mg/kg, i.p.) and xylazine (10 mg/kg, i.p.). A total of 10 rats were submitted to aortic stenosis