Anti Bacterial And Anti Parasitic Properties

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Licochalcone A Licochalcone A is classified as a chalconoid, a type of natural phenol. It is harvested and extracted from the root of the liquorice plant, Glycyrrhiza glabra. First utilized for its anti-bacterial and anti-parasitic properties, it has recently been tested and shown to be effective in treating hyperpigmentation by inhibiting tyrosine production by binding to tyrosinase and slowly catalyzing it (Chang, 2009). This would group it as a “true” tyrosinase inhibitor. It is also a competitive inhibitor, since it is able to bind to TYR’s binding site, L-dopa) and restricting the substrate from binding. Other effects of Licochalcone A Licochalcone A has been shown to have a number of different effects on developing embryos. Some of…show more content…
Other effects, such as anti-cancer, cannot be observed in this study due to time and resource constraints. Zebra Danio as a candidate for study Zebra Danios, also known as Zebrafish, and by the scientific name Danio Rerio, are a member of the minnow family of fish: Cyprinidae. Zebra Danios are an ideal candidate for scientific study for a multiple of reasons. They are a beginner level fish, meaning that they are easy to care for and maintain. They are tolerant of a range of water temperatures and pH as well as not being fussy eaters. They are readily available at most major and minor pet stores. They are also viewed as an entry-level breeder. The advantage of breeding Zebra Danios are plenty. Female Danios lay many dozens of eggs per day when ready to spawn. The eggs are fully transparent which allows for ready observation of development at every stage of development. Gestation periods were also very quick when compared to other animals. Normal gestation periods in Zebra Danio are 48 hours long. Because of this, observation and analysis of experimentation on danio development. Zebra danios were among the first fish to be genetically manipulated to the extent that lab-produced florescent varieties, Glofish®, have been developed and even trade-marked. Zebra danios were selected for this study because of their availability and the transparency of the eggs. This would allow for easy photographing of the eggs at different stages
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