Anti-Epileptic Medication Coverage Analysis

Despite the difference in group sizes and the length of time monitoring any re-occurring seizures the review still came to the same findings that no significant difference in adverse effects between paracetamol and the placebo treatment. (Mewasingh, 2014).

There are many current drugs and therapies for seizure illnesses. One example of these drugs is, carbamazepine (epitol). Epitol, according to webmd.com, works in the sense of

A seizure is another synonym for the term epilepsy. It is the 4th most common neurological problem in US. More than 3 million on an average are experiencing epileptic seizures at any point. While the other more frequent mental issues are Alzheimer’s and migraine problems. The frequency of seizures, their timings of occurrences is unknown and unpredictable. About in 70% of the cases these can be controlled and cured to a large extent with prescription medication and prevents a number of deaths. Using medication is the first thing that is preferred and suggested by physicians to control seizures before going for surgeries. There are various causes behind the frequent episodes of

Different seizure medicines tend to yield different types of side effects. Just because a certain effect is common with one medication, however, does not mean that the individual will experience it. Many people have few or no problems with side effect. Some side effects are associated with specific medications and occur fairly frequently. Examples of some idiosyncratic effects are listed here. Of note, these will vary from one drug to another. Common dose dependent side effects are usually related to symptoms of the central nervous system and occur with higher dose amounts. Dilantin is often initial drug of choice. Prescribers have to be careful in switching from generic to trade name as bioavailability may vary and can lead to toxicity).

The results showed that as many as 46.2% of epilepsy patients taking antiepileptic medication adherence rate in the medium category. While the level of quality of life of epilepsy patients are categorized either as many as 58.5% of patients. Antiepileptic medication adherence is significantly associated with quality of life of epilepsy patients (p = 0.001 <0.05). The higher level of antiepileptic medication adherence, the quality of life of patients with epilepsy will be getting

1. Concerns associated with adverse effects: • Anterograde amnesia: have been associated with anterograde amnesia. • Paradoxical reactions: including hyperactive or aggressive behavior, predominantly in adolescent/pediatric or psychiatric patients. • Suicidal ideation: various antiepileptics showed an increased risk of suicidal thoughts/behavior.

Michael Martins was seen in followup for history of seizures. His seizures continue under good control on Lamictal 200 mg tablets, 2 tablets b.i.d. and Topamax 300 mg (a 200 mg and 100 mg tablet together, twice daily). He is having no difficulty with these medications. He receives the brand name Topamax and Lamictal. He has had no seizures since last seen by me six months ago

Anti-seizure medications and antidepressants are sometimes prescribed to patients who haven't found relief through other medications. These medications can change how the body senses pain and bring relief.

The pharmacokinetic of absorption of gabapentin is not linear unlike other newer anti-seizure medications. The explanation for this event is because gabapentin absorption depends on

In cases of the partial seizures with or without the secondary generations drug can be used as an adjuvant therapy.

Drugs for control of seizures may also affect learning and bring down the scholastic performance in children.

Whereas, in PTZ-induced seizures, augmented effects were obtained when nifedipine was combined with sodium valproate [2].

In real life there are corrupt scientists who will do whatever it takes to receive popularity. Pharmaceuticals are an industry that is especially well acquainted with this area. Depakote is a little known, yet, versatile drug. Originally, Depakote was used as a seizure medication , but through sheer faith in an unproved theory was it tried in the treatment of

Use of fluoroquinolones, which have been a cause for concern to their risk for TdP (23), are not promoted as first line (22). Safety issues have also been raised for use of QTc-prolonging antipsychotic medications (2; 24). Such drugs are frequently used in hospital inpatients as delirium can affect a fifth of acute medical admissions (25). NICE guidelines allow for the antipsychotics haloperidol and olanzapine to be used for up to one-week as a therapy for delirium (26). Whether QTc contributes to increased hospital mortality in those with delirium is unknown (27). Prolonged QT interval is known to predict mortality in a variety of other conditions that are frequently encountered in the AMU such as: coronary artery disease (28), heart failure (29) and diabetes mellitus (30; 31). Our data have shown in-hospital mortality of 3.8% in those with normal QTc and 6.0% of those with long QTc. The study was not powered for this outcome but such a difference would be clinically relevant; based upon these data, approximately 1500 patients in each group would need to be studied to detect a difference with 80% power and alpha of 5%. A more prolonged length of stay with long QTc in unadjusted analysis was unexpected but was no longer significant when correcting for patient age and presence of diabetes or electrolyte disturbance.

Levetiracetam is probably a major breakthrough in the treatment of epilepsies. It is a highly effective, broad-spectrum, one of second generation AED with a unique mechanism of action.