Anti Inflammatory Drugs ( Nsaids ) Essay

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Last week’s forum we have discussed nonsteroidal anti-inflammatory drugs (NSAIDs), which in 1993 was classified as a symptom- modifying anti-rheumatic drugs [S-MARDs] (Buer, 2015, p. 168). This week we shift our focus to the role of disease-modifying antirheumatic drugs (DMARDs) as a pharmacological management for rheumatoid arthritis. Romão, Canhão, and Fonseca (2013) stated that methotrexate (MTX) is the most commonly utilized DMARD. As referenced by Romão et al. (2013), MTX is the gold standard for rheumatoid arthritis (RA) treatment due to cost effectiveness, safety, efficacy and is the drug mostly adhered to by patients with RA (p.17).
Rheumatoid arthritis is a debilitating disease believed to be mediated by the inappropriate activation of immunologic response (Goodman & Fuller, 2009). In 2010, a joint working group of the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) modified the 1987 ACR criteria used to identify RA. The modification was necessitated because of the need for emphasis on the serology and acute phase reactants rather than joint inflammation in the detection of RA in its early phase (Singh & Cameron, 2012, p. S3). Early detection is the key to the effective management of RA, both pharmacologically and pharmacologically. As a physical therapist, I have seen the associated activity limitations and the disability as a result of cartilage destruction, bony erosions and joint damage in
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