Anti Inflammatory Drugs ( Nsaids ) Essay

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

The type of treatment chosen depends on the type of arthritis and the effects it has on the patient as well as the severity of the disease. Other factors to consider are the age of the patient and the joints affected. Bearing in mind that different people exhibit different reactions to different medications, treatment in this case is individualized but includes a combination of joint protection methods and medication. For rheumatoid arthritis, the Initial treatment starts with non steroidal ant inflammatory drugs and other simple analgesic but as the inflammation progresses, slow acting anti rheumatoid drugs which are aimed at modifying the disease are introduced. They are added progressively as the inflammation progresses in order to suppress the process that leads to chronic inflammation (Amin 1995).

Prescription and over the counter drugs. If you asked the vast majority of people in the US if there a problem with more of the well-known prescription and over the counter drugs they would tell you no. Take ibuprofen for example, many people think that this drug is absolutely safe with only a very small chance of it harming you in any way. But just last year the FDA has strengthen the warning on all NSAID’s. NSAID’s stand for non-steroidal anti-inflammatory drugs, and ibuprofen lands in that category. While many people don't take medicine that say ibuprofen many you might be taking something like Motrin or Advil, and these to fall into the category of NSAID’s.

Rheumatoid arthritis is an autoimmune inflammatory disease which causes inflammation on joints leading to disability. The deterioration is caused by constant attack in the synovium leading to synovial cells to a rough and grainy tissue eventually allowing the bones to crumble away. The disease currently has no cure and scientists are thriving to find a target specifically aiming at the bones.

Around 70% of arthritis sufferers in the UK have rheumatoid arthritis (RA). Women are also more likely to develop RA than men, and commonly affects adults between ages 50 and 60. This condition is characterised by an insidious onset of pain, swelling of joints and morning stiffness. Arthritis is caused by inflammation of the synovial tissue of the joints, supposedly triggered by the presence of autobodies such as rheumatoid factors. The first line treatment for RA is a combination of disease modifying anti-rheumatic drug (DMARD). These slow down the progression of RA and treatment typically includes methotrexate in combination with another DMARD (e.g. sulphasalazine). Short term glucocorticoids are also used with DMARDS to manage flares of inflammation. Anti-TNF drugs

Rheumatoid Arthritis is a systemic autoimmune disorder. There are more than 100 different types of Arthritis, yet it is estimated that it affects approximately 1% of the population in the Western World. The disease is generally diagnosed in middle aged adults and the elderly. In rarer cases, children can also develop the disease and it is called Juvenile Rheumatoid Arthritis. Women are three times more likely to have rheumatoid arthritis than men. (Stevens) Many people living with Rheumatoid Arthritis appear to be healthy individuals, but suffer internally. Today, I will discuss what rheumatoid arthritis is, how it is diagnosed, and how it affects the body.

Rheumatoid arthritis (RA) is a systematic inflammatory disease characterized by synovitis (constant inflammation of the synovial membranes) and autoantibodies. The disease that affects 0.5-1.0% of all adults in industrialized countries, mostly women and elderly people (Scott et al, 2010). In the United States, more than 1.5 million people suffer from rheumatoid arthritis, making it one of the most common auto-immune disease (Carmona et al. 2010). According to the Arthritis Foundation, individuals who suffer from arthritis have to deal with joint pain, morning stiffness, fatigue, loss of appetite, depressive symptoms, and low-grade fever which can last a few days to weeks. Individuals with this disease tend to have a low-quality of life and difficulties with day-to-day activities.

Biologics first made their premier as a treatment option for Rheumatoid Arthritis (RA) over fifteen years ago, when Enbrel was first introduced. Now it is one of the front runners for treatment of RA. Many studies and articles, such as Palmer’s (2012) article out of the British Journal of Nursing, has shown how beneficial and impactful Enbrel has been as a treatment option. Enbrel.com proclaims how symptoms start to improve in as early as two weeks, with most people seeing improvements within three months, with even more improvements seen by six months. The article by Dhillon, Lyseng-Williamson, and Scott (2011) states that in several well designed trials in patients with early or long-standing

Rheumatoid Arthritis known as RA is an autoimmune disease which the body’s immune system mistakenly attacks the joints. In a healthy individual the immune system protects by attacking foreign substances like bacteria and viruses. When this happens the body will create inflammation that causes the tissue that lines the inside of the joints known as the synovium to thicken, which creates swelling and pain around the joints. If the individual is to go a prolong period without treatment for RA it can damage the cartilage and over time the loss of cartilage the joint can then become loose, unstable, painful and most lose their mobility. Joint deformation can occur and the damage to the joint cannot be reversed.

Rheumatoid Arthritis is a growing and life- changing disease in Australia, creating negative social and economic consequences for both the individual patient and society. A disorder in which the body attacks its own healthy cells and tissues resulting in limited movement and inflamed joints in the body. Rheumatoid Arthritis has been chosen as a National Health Priority Area as it is a prevalent disease and the conditions are a significant cause of disability. The topics being discussed in this essay will include the definition of the disease Rheumatoid Arthritis: reasons for inclusion as a priority health issue focusing on the incidence and prevalence in the Australian population, risk factors for developing Rheumatoid Arthritis and

Today in the United States there is an estimated 1.3 million people living and dealing with rheumatoid arthritis (Arthritis Foundation). One might ask, what exactly is rheumatoid arthritis? Well, rheumatoid arthritis, also commonly known as RA, is a form of inflammatory disease and an autoimmune disease. If the person is a minor, or below the age of six-teen, then the chronic disease can also go by the name of juvenile arthritis. The juvenile arthritis is, “Defined as chronic inflammation of the synovial joints, with unknown etiology, which starts before the age of sixteen and persists for at least six weeks” (Hink et al 1). This disease can affect anyone with a functioning immune system. Out of the 1.3 million people in the United States that have rheumatoid arthritis, 70% of that number is women (RA.com). Once again there are no certain reasons as to who receives this disease whether its children, elders, Caucasians, African Americans, etc. But once they do receive the illness, then it affects them immensely. “The disease is systemic, meaning it can occur throughout the whole body. It’s a chronic disease, so it can’t be cured” (Arthritis Foundation). The pain, stiffness and fatigue can affect the entire body. “RA occurs when your immune system, the system that protects your body from outside harm, mistakenly starts attacking healthy tissue” (RA.com). Rheumatoid arthritis is an incurable disease that is affecting

In addition, the symptoms of rheumatoid arthritis and other types of arthritis diseases can be similar that makes the diagnosing process inaccurate. According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases, “doctors use a variety of tools to diagnose the disease and to rule out other conditions.” [3] For example, doctors usually ask the patients about their family's medical history and observe the patients' ability to do daily living activities. After diagnosing the disease, doctors use several methods to treat the disease at different times depending on the patient’s condition. However, all doctors want the same goal, which is to relieve pain and stop the damage in the joints. Most people with rheumatoid arthritis take medications. For example, using nonsteroidal anti-inflammatory drugs to reduce the inflammation. Furthermore, according to the Better Health Channel, “rest can help [patients] to manage fatigue, and is particularly important when [their] joints are swollen.” [4] Taking regular rest periods during activation will also reduce the pain and the

Rheumatoid Arthritis (RA) is a systemic inflammatory autoimmune disease associated with swelling and pain in multiple joints. First joint tissue to be affected is the synovial membrane, which lines joint cavity. Multiple immune-regulatory cytokines (such as B-cells and interleukins) contribute to joint damage. Eventually, inflammation may spread to articular cartilage, fibrous joint capsule, and surrounding ligaments and tendons, causing pain, joint deformity, and loss of function.

Rheumatoid Arthritis, which is abbreviated as (RA), by definition, is an inflammatory immune-mediated defect. In developed countries, its prevalence is about 0.5 to 1%. It is a serious disease whose effects can at times lead to permanent disability. Some of the effects include bone erosion, articular destruction and chronic synovial inflammation, which results in functional decline and disability. The Introduction of effective and efficient intervention has been put in place to reduce joint damage and functional impairment.