Anti Tumor Effect On Tongue Cancer Using Animal Model Essay

According to the oral cancer foundation, “Chemotherapy is the use of chemicals to destroy cancer cells. Chemotherapy works by interfering with the cancer cell's ability to grow. It is one of the three main methods utilized to treat cancer.” With cancer being a potentially fatal disease it is important to diagnose it as soon as possible. the oncologist have to study the chemicals used so that they can determine what chemicals will treat the cancer or disease the best and what chemicals can be mixed together without any major side effects. The drugs can be divided into groups based on how they work, their chemical structure, and their relationship to other drugs.

may help kill certain cancer cells and reduce the size of others. Evidence from one cell culture study

The extracts and polyphenols suppressed cell proliferation, promoted apoptosis, modulated signaling transduction, inhibited cell invasion, and prevented angiogenesis and metastasis in animal models related to multiple types of cancer such as liver, bladder, prostate, intestine, colon, pancreas, and mammary gland in more than one hundred publications (Yang & Wang, 2010; de Moura et al., 2013). Green tea has been studied expansively for its cancer prevention effects which are believed to be associated with green tea polyphenols known as "catechins (-)-epigallocatchin-3gallate (EGCG), (-)-epigallocatechin (EGC), (-)-epicatechin-3-gallate (ECG), and (-)-epigallocatechin (EC)...they each have a level of antioxidants and are strong metal ion chelators, which prevent the formation of reactive oxygen species (ROS)" (Yang & Wang, 2010, p. 931; Ziech et al., 2012). Further research has revealed that high concentration levels are necessary to accomplish this, and adding other agents such as Atrovastatin, a drug used to lower cholesterol, increase success (Yang & Wang, 2010). EGCG has demonstrated the most success because it "serves an antioxidant, or pro-oxidant, and

Eighteen People a day are diagnosed with oral cancer. ("Facts and Figures"). Roughly 48,250 Americans will be diagnosed this year. As well as, it will cause approximately 9,575 deaths in the next year ("Oral Cancer Facts"). This is a big deal. Oral cancer is a deadly disease. ("Risk Factors") The three main factors that contribute to oral cancer are genetics, environmental factors/lifestyle choices, and chance.

Bacterial infections are causative factors for cancer that have been widely overlooked. Studies in the 90's have shown the bacteria Helicobacter pylori to be a primary cause for gastric cancer. This discovery revolutionized the association between microbial agents and cancers. More recently, studies involving microorganisms in the oral cavity have shown connections to cancerous growth. The inflammation caused by the bacteria P. gingivalis actually leads to changes in cell responses- including those involved in cell death and cell division.

Oral cancer is a devastating disease. Over eight thousand American lives are taken by oral cancer and only a fourth of these patients do not excessively drink alcohol or smoke tobacco, which are the two main causes of oral cancer (The Oral Cancer Foundation). Survival rates for oral cancer could be much higher if the population would take precautionary measures to reduce their chances of being diagnosed with oral cancer. When the use of alcohol and tobacco are decreased, the chances of acquiring oral cancer are also decreased. By visiting the dentist at least once every year, new lesions could be found. Unfortunately, only seven percent of the population, who visits the dentist regularly, receives a thorough oral cancer exam(The Oral

You may be asking yourself, “what is Head and Neck Cancer?”. Well in this report it will be my job to explain what it is. Head and Neck cancer can have many definitions but the one that i’ll be using is, it is different sort of cancers in between the head and the neck. According to the Cancer Treatment Centers of America, “For example, the most common cancers that someone can get are cancer in the ears, nose, and throat. For example, tumors in the larynx or pharynx may be discovered as a lump in the throat. Cancer in the mouth may cause sores in the mouth or swelling of the jaw.”

Cancer is a condition that is related to inflammation. Scientists are curious about how curcumin can help fight cancer since it is seen to combat inflammation. The results demonstrate that it may help avoid cancer and additionally cure existing conditions. Turmeric is also found to be beneficial in delaying the development of tumors. The scientific studies also

The antioxidant and tumor inhibiting property of Brahmi were studied in 3- methylcholanthrene induced fibrosarcoma rats (Rohini et al., 2004). The levels of the antioxidant enzymes such as glutathione peroxidase, superoxide dismutase, catalase and glutathione, the rate of lipid peroxidation (LPO) were determined in the liver and kidney tissues. Sarcoma induction in rats resulted in a marked increase in the rate of LPO and a decrease in the antioxidant enzyme status. Furthermore, tumor markers such as lactate dehydrogenase, alanine transaminase, aspartate transaminase, creatine kinase, and sialic acid showed an upregulated expression in the serum. Brahmi supplementation enhanced the antioxidant enzyme status, reduced the rate of lipid peroxidation and downregulated tumor development markers. Among the five crude samples such as the whole plant of Bacopa monniera (L.)Wettst and four different fractions (petroleum ether, CHCl3, EtOAc, and n-BuOH fractions) of the methanol extract, n-BuOH fraction was noted to have the highest antitumor activity as per bioassay-guided methods conducted by Peng et al. The dammarane triterpene saponins isolated from n-BuOH fraction, bacopaside É (1) and bacopaside VII (3), had

At the beginning of the 21st century, cancer continues to remain a global health problem. Worldwide, cancer is the leading cause of death after cardiovascular

The lemon has anti-cancerous characteristics because it creates an alkaline environment that destroys the cysts and tumors. When the organism’s environment is alkaline the tumors cannot grow and spread, since tumors feed on acidic substances. When there is no acidity in

Oral Squamous Cell Carcinoma (OSCC) is the most common cancer of head and neck region.1 Each year it affects as many as 274,000 people around the world and 2-4% in western countries and 40% in Indian subcontinent.2 The incidence of oral cancer has both familial and genetic predisposition. It is commonly associated with the risk factors like chewing of tobacco, areca nut and betel quid. In developing countries this is often an indicative pattern causing high prevalence unlike developed countries where cigarette smoking and alcohol consumption is more common and prevalence is rather less.3, 4 Lack of early diagnosis is another key factor, may be either due to negligence of early lesion by patient or sample examination by health care workers.3 Early diagnosis has shown chances of 5-year survival rate as high as 80% of cases along with decrease in patient morbidity and suffering.3

In today’s society most people think that the leading cause of oral cancer are things like tobacco products or other types of drugs. But that is not the case, because scientist have proven that the leading cause is really oral sex.

Each person knows about Breast cancer these days, due to the fact that humankind witnesses countless organizations working for this sole purpose diligently every day. Periodically we meet or hear individuals struggling with this devastating category of cancer which is particularly prevalent in women. According to the recent facts and figures from American Cancer Society about the number of deaths from breast cancer in US in 2013, among all ages, has gone up to 39,620. This portrays a massive number, nevertheless analyzing the mortality trend from 1990-2010, one can grasp the death rate has been decreased to 34%. Consequently, the known reason behind this decline is attributable to the improvements in our health care system in terms of treatment, in conjunction with the early detection of breast cancer. Discussing about the risks of having breast cancer, we all know that there are certain factors which can’t be modified that comprise sex, family history, age, early menarche, and late menopause; however, there are several factors which can be taken care of for instance abstinence from smoking and alcohol consumption, use of combination oral contraceptives, avoiding obesity, and increase the usage of vegetables and fruits in your diet could prevent significant proportion of population from getting this cancer. Nevertheless, when populaces mention the dietary changes that can give an enormous benefit against cancer, the aforementioned will find a vast amount of natural products

Dietary stearic acid has an aptitude to induce breast cancer cells apoptosis (Hardy S et al, 2003) and cell cycle arrest (Li C et al, 2011).On carcinogenesis models (A/ST mice) stearic acid reduces the configuration of tumor against mammary adenocarcinoma cells (Bennett AS, 1984).Epidemiological study reveals that breast cancer prevention and treatment by stearic acid shows successful results (Saadatian-Elahi M et al, 2004).Cancer treatment potency can be enhanced by the conjugatory action of dietary substances and