Antibiotic Resistance And Its Effects On Nonpathogenic Strains

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Microbiology Research Paper: Antibiotic Resistance and its effects on nonpathogenic strains in the microbiome Lourdes Samantha Valencia MW Microbiology 12 Matthew Schweitzer Fall 2015 Antibiotic resistance had been a crisis in the United States for many years now. According to the CDC, “up to 50% of the time, antibiotics are not optimally prescribed, often done so when not needed, [or with] incorrect dosing or duration” (CDC). More and more bacteria are becoming antibiotic resistant mostly due to incorrect amount and length of dosage, while sometimes, even the actual antibiotic is incorrectly given to the patient. Because of this, many strains of bacteria had become resistant to these antibiotics and thus, have infected more and more…show more content…
Determining pathogenic bacteria in a sample and its specific antibiotic treatment is an important step in combating antibiotic resistance. For example if a broad spectrum antibiotic, like a tetracycline, was given to treat a patient who wanted to treat salmonellosis, it will also target other gram-negative and gram-positive bacterias. Patient zero, in this case, may have been taking a broad spectrum antibiotic that may have targeted a vast amount of bacteria in their body, killing some of the microorganisms in their microbiome. This loss of microorganisms gives way to opportunistic microorganisms to attach itself to a surface where it can infect the host. Additionally, the use of a broad spectrum antibiotic can cause the microorganisms not susceptible to it to become resistant. These microorganisms then can become drug-resistant and opportunistic and can lead to a secondary infection, like Clostridium difficile. As this particular study showed, multi-drug resistant organism (MDRO)-associated bacteremia is a problem for patients receiving anti-cancer chemotherapy (Moghnieh et al., 2015). Because of this, “the empiric use of broad-spectrum antibiotics in febrile neutropenia is very critical” (Moghnieh et al., 2015). On the positive note, it decreases the mortality in the fibril episode in people with fibril neutropenia, but it also a risk factor for “emergence bacteremia with
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