Antibiotic Resistance And Its Effects On The Human Body 's Immune System Essay

Antibiotic resistance is a phenomenon in which germs evolve to be able to resist the action of drugs. This causes illnesses that were once easily curable with antibiotics to become dangerous infections, requiring alternative medications or higher doses. With millions of deaths increasing every year, antibiotic resistance has become one of the world's most pressing public health problems. This essay will explain the key causes of the emergence of resistant bacteria, including antibiotic misuse, inappropriate prescribing and availability of few new antibiotics, and outline relevant effects of antibiotic resistance.

One environment where bacteria are regularly exposed to antibiotics is in large livestock operations, where producers very often treat their cows and other animals with drugs to prevent epidemics in the unsanitary and overcrowded conditions, which are common in the livestock industry. The simple reason for this is that in the short term it is cheaper to drug up the animals with antibiotics than to keep a clean living environment for them. Another big reason for these producers to drug up the animals is the fact that feeding antibiotics to the livestock makes for larger animals. The problem occurs when bacteria in these animals survive the bombardment of antibiotics, and some always do, the

When antibiotic is used most of the bacteria die but a few bacteria with antibiotic resistance gene survive and reproduce and pass this advantage to their offsprings. This selective pressure exists naturally, however antibiotic misuse can be accused for fastening the spread of the antibiotic resistance gene [Refer to figure 2] (Learn Genetics 2015). Consequently, inappropriate antibiotic intake will lead to a greater chance of superbugs being developed. Antibiotic resistance can be defined as a new ability which a bacterium has developed to stay unattached in the presence of an antibiotic that was previously effective to destroy the bacterium (ABC science 2015). Four key mechanisms that has been identified for bacterial antibiotic resistance can be listed as: producing enzymes that inhibit the functionality of the drug, reducing the effectiveness of the drug by producing targets against which the antibiotic, reducing the permeability of the drug into the bacterium and active export of antibiotics using various pumps (Pogson 2012). All these mechanisms can be developed by any of the bacteria when the corresponding mutated gene of antibacterial resistance is received. The genes code for specific proteins, and variation in the gene leads to alteration of the shape of proteins. This leads to changing the functionality

Widespread use of antibiotics has been very controversial in the media as well in the general population. Due to these controversies, it is very misunderstood to how antibiotics work leading to many patients in the hospital setting wanting to take them when it is not necessary or refusing to take when it is necessary for their survival. Some of this controversy is due to antibiotic resistance, which has spread an alarming rate in the 21st century (Walsh, 2000). Antibiotic resistance is the result of very strong bacteria or microbes that are resistant to the antibiotic prescribed and those microbes accumulate overtime by their survival, reproduction and transfer, leading to increased levels of antibiotic resistance.

In an era where common people are perhaps more health-conscious than ever before, it is mainstream knowledge that meat treated with antibiotics and hormones may not be safe for consumption. Many chain restaurants, such as Chipotle, Chick-Fil-A, and now Subway, will only buy meat from non-antibiotic suppliers, in order to meet increasingly high consumer standards. However, less than fifty years ago, meat from antibiotic treated livestock was actually preferred. What triggered this change in the way consumers scrutinize their food? It can be largely attributed to the research of one Stanford biologist and former Commissioner of the FDA, Doctor Donald Kennedy. Through opening the medical community’s eyes to the potential dangers of antibiotic resistance, Donald Kennedy shed light on one of the most troubling phenomena of modern medicine. However, before he was a Harvard graduate and esteemed biologist, Kennedy was a child growing up like any other in a New York City stricken by the Great Depression.

Also known as superbugs, these bugs are resistant to our modern day antibiotics. People around the world are trying to figure out alternatives to this plague. These bugs have evolved over years and years becoming stronger and passing down genes from generation to generation, To slowly become the super bugs that they are known as today. Often these resistant genes are caused by overuse of antibiotics by humans and farm animals, but this is not always true. Recently the ARS (the American Recorder Society) found antibiotic resistance in prairie soils that had no human contact. Antibiotic resistance is commonly viewed as a result of antibiotic overuse in humans and animals, Recently found antibiotic-resistant

Antibiotic resistance is and continues to be a global public health issue1.One of the main concerns stems from the ability for bacteria to obtain antibiotic resistance very easily as a result of chromosomal changes, or through plasmids and transposons which generate an exchange of genetic material2. Resistance can also result from single or multiple mutations1,3. To combat this rising force, scientists must research and analyse the many possibilities of mutations in a variety of genes and proteins in specific bacteria and ways to combat them.

Flues, colds, and diseases flow in and out through all seasons of the year. The illnesses caused many patients to go to the doctors and to get help. In return, the patients will likely get antibiotics prescribed by the doctors. Antibiotics are drugs or a type of medicine that will prevent or inhibit bacteria which is causing the infection. Many people think that antibiotics can completely cure their infection by taking them, but many people do not realize the importance of antibiotic resistance and the evolution of bacteria.

Antibiotics has played a huge role in the field of medicine since it was first discovered in 1928. Antibiotics are antimicrobial drug that kills or inhibits growth of diseases which prevents many illnesses. However, in the past decade, Antibiotic resistant bacteria has become the world’s latest pandemic. Many strains of bacteria have adapted and developed resistance against antibiotics. According to the CDC, “at least two million people are infected with bacteria that are resistant to antibiotics and at least 23,000 people die each year as a direct result of these infections.” (CDC) This is a problem because antibiotics are the number one defense tactics against bacterial infections. Without this line of defense, people vulnerable to bacteria growth which can cause problems in health.

Antibiotic development is one of the modern marvels of medicine. This is the first external tool that people have to fight against bacterial infections. The first drug developed was Penicillin. This medication is so effective that it is still used today. From its structure, every other antibacterial drug was developed. Today, there are hundreds of options available for treating infections. Unfortunately, this has had significant ramifications on the development of resistance to these medications. As the infections continue to learn and evolve, it is important that people educate themselves on what this means and the impacts it has.

When penicillin was first administered in 1943, it proved to be extraordinary at wiping out nasty cases of syphilis, tuberculosis, gonorrhea, and meningitis infection. With the threat of these deadly infections in ‘check,’ pharmaceutical industries then cut back on their research to discover even more effective antibiotics. This new-found medical confidence inspired patients to merrily run to the clinic to get penicillin prescriptions for everything from nausea and diarrhea to running nose and sneezing, and doctors to happily prescribe the ‘miracle drug.’

Antimicrobial resistance might affect the economy in a variety of ways. One way that antimicrobial resistance might affect economy is by financially affecting hospitals. To be specific, antibiotic resistance might increase the length of stay (LOS) and direct treatment costs among hospitalized patients, so hospitals are bearing a high financial burden. Antonanzas, Lozano, and Torres (2004) found that the treatment of methicillin resistant S. aureus (MRSA) infections increase the financial costs for hospitals, as a result of higher direct costs and longer LOS than those related to methicillin-susceptible-susceptible S. aureus (MSSA) patients or MRSA-free patients. They found that the incremental length of stay (LOS) is in the average of 2–10

Antibiotics have become a very important part of medicine. It is used to treat all kinds of bacteria, infections, diseases. Sadly, antibiotics have been coming to an end, they are being used more and more often everyday. They are being used so much that the bacteria they are being used to treat have been starting to become resistant to these antibiotics. Many infections that were once so easy to be treated have been gaining a stronger resistance. This is because of how the bacteria have a special enzyme that kills and eats up the antibiotics. As well as how the resistance that bacteria have can easily be passed off from one bacteria to another. This makes the resistance to antibiotics spread faster and increase rapidly. Much of the bacteria with resistance usually have it in their genes.

In its most recent report, the World Economic Forum Global Risk committee listed antibiotic resistance as one of the greatest threats to human health5. In the United States alone, is is estimated that over

According the World Health Organization (WHO), antibiotic resistance is one of the world’s greatest health threats to date (Haddox, 2013). In the article, The Health Threat of Antibiotic Resistance, Gail Haddox (2013) discusses the danger antibiotic resistance poses in today’s society and strategies to prevent the expansion of antibiotic resistance. In Europe alone, an estimated 25,000 deaths have been attributed to multi-resistant infections (Haddox, 2013). Common infections are now harder to treat due to the increased resistance to antibiotics across the world, in fact some are becoming untreatable. Antibiotics should be treated like oil, a non-renewable resource (Haddox, 2013).