Antidiabetic Medication Analysis

No one wants to lose their mind. But the reality is that the risk of dementia doubles every five years after the age of sixty-five. Is there anything that can be done to prevent this age-related loss of brain function? Are There Ways to Reduce Dementia Through Lifestyle Changes? European researchers analyzed 1,433 people over the age of 65 to determine what lifestyle factors would reduce the risk of dementia the most. After getting a complete medical history on the participants, they tested their cognitive function at intervals over a seven year period. What did they find? According to this research, the two best ways to reduce the risk of dementia is to eliminate diabetes and depression - both of which are dementia risk factors. If both of these factors were eliminated and more people were encouraged to eat fruits and vegetables, the number of new cases of dementia would drop by 21%. There 's some controversy as to whether depression actually increases the risk of dementia - or whether it 's simply an early sign of the disease. This study suggests that depression probably does increase the risk of the disease - and isn 't just a symptom. It 's not surprising that diabetes is a risk factor since it 's associated with insulin resistance. Some studies show insulin resistance increases the risk of dementia. Another way to reduce dementia risk is to encourage people to be literate and educated. This study showed that the number of new cases of dementia would drop by 18% if

One of the most prominent and perhaps most feared condition associated with aging is dementia. The family of disorders can cause individuals to lose their mind, reducing one from being a complex, thinking, feeling human being to being confused and vegetative, unable to recognize their loved ones. Serious dementia affects nearly 37 million people globally, but predictions of how those numbers will change over the next few decades are conflicting (textbook). Although we know dementia as to do with damage to nerve cells in the brain, there are ongoing studies looking at correlations between other health issues and these types of diseases.

Recent studies indicate that limiting the use of certain medications can improve a senior's life. One study, conducted by researchers at Indiana University, finds that the prolonged use of anticholinergics may cause physical changes within the brain that could lead to dementia. Furthermore, The Canadian Foundation for Healthcare Improvement (CFHI) released information related to a program it started in 2014: This study examined how the discontinuation of antipsychotic medications affected the seniors who were taking them to treat dementia. The results indicate that seniors’ lives may improve when antipsychotic medications (that are being used to treat dementia) are discontinued.

The necessity to integrate this knowledge when caring for the older population is desirable because the population above 55 years is among the fastest growing population in America according to the U.S. census (2010). Tolson Booth & Schofield (2011) discuss that older people are at a greater risk of developing delirium following an age-related impairment of cerebral metabolism, which causes a significant decrease in the synthesis of neurotransmitters, in particular, acetylcholine. According to Hosie, Lobb, Agar, Davidson, and Phillips (2014), older people are often affected by at least one chronic condition such as dementia. Unlike delirium, dementia is a chronic condition that lasts at least six months and in most cases occurs progressively. Also, the most common form of dementia, Alzheimer’s disease (AD), is associated with a chronic decline in acetylcholine (Redfern & Ross, 2006). Therefore, this explains why symptoms of dementia and delirium overlap, especially memory loss in both conditions. The overlapping symptoms, therefore, make differentiation between the two conditions difficult, especially when delirium is superimposed on dementia. It is because of this that identifying delirium is of great significance to the older population.

As a person ages, there are some mental health issues that can arise. Two common disorders that come with age are Alzheimer’s and dementia. Both conditions have something in common, a person’s mind is altered due to forgetfulness. A person may not be able to retain information as easily as they once had. People with these conditions may forget how to perform simple, everyday tasks. One task that may be affected is taking medications. Another fact that comes with age is that people may start taking several medications for health conditions they may have developed over the years. It is important that people take these medications as prescribed, but because they may have dementia or Alzheimer’s they do not remember how or when to take their medications.

The life is beautiful, nothing is impossible. This documentary about simple raw reversing diabetes in 30 days. Diabetes is chronic disease and have two types (type one produce very little or no insulin usually accrue in children , type two diabetes don’t produce enough insulin this type common in the females than males).This disease is "major pandemic situation" because 246000 of people had it and 1 out of 3 children born after year 2000 will get it .I learned this information from the documentary and some subjects I had it in this semester. In the beginning I felt bored when I saw this documentary but I enjoyed and interested it later. In the documentary they choose people from different places in America.

Life is full of many obstacles that one must overcome to reach success in life. When I had just barely turned 14 years old I was posed with some of the toughest news I had ever faced. One week after my birthday, on Christmas Eve, I was diagnosed with Type 1 Diabetes.

diabetes, chronic infections, inflammations, and hereditary. Aging People with diabetes are at a higher risk of developing Alzheimer’s disease (Marsa 54). Excessive brain specific insulin resistance impairments and signaling, account for many Alzheimer’s abnormalities. Brain insulin signaling regulates food intake, body weight, reproduction, also learning and memory. Defective insulin signaling results in cognitive ability decrease. Studies have also shown a link between chronic infections and inflammation in patients that develop Alzheimer’s disease. Viral and bacterial chronic infections, which cause cumulative damage, are an inflammatory vessel for Alzheimer’s disease. Infections have the potential to initiate a surge of events leading to inflammatory conditions of the central nervous system by generating free radicals and nitric oxide (Monastero et al. 107). There is an association between cognitive decline and systemic inflammation and infections. Successful treatment of chronic infections and inflammation is difficult but important in the effort of improving the quality of life in an Alzheimer’s patient. Alzheimer’s disease is not a normal part of aging; however, researchers know that genes play a part in the disease. There is a

We aim to improve the process by which diabetic medication is administered in the medical surgical unit. The process begins with nurses reviewing medication orders and ends when patient receives medication. By working on the process we expect better patient outcomes as evidence by better controlled serum glucose levels and fewer instances of patient hyper/hypoglycemic episodes. It is important to work on this now because uncontrolled blood glucose levels can cause longer hospital stays, increased risk of infection, and initiation of new, additional comorbidities.

Alzheimer’s is increasing and those 65 and up has a greater chance of being possibly diagnosed with this hopeless disease in later adulthood because learning and long term memory abilities decreases. (Kroner, 2009) Diabetes is a well-known risk factor for Alzheimer’s disease that effects the elderly and individually are appalling diseases. The connection between Alzheimer’s and diabetes has yet to be determined, therefore studies are being completed to find the connection between the two diseases. Diabetes is the condition in which the body does not produce enough insulin to function properly, in which food is not processed properly for energy causing elevated levels of glucose in the blood. Simply, not enough insulin equals glucose (used for

the result of poor diet and a sedentary lifestyle. In order to help lower cholesterol levels, studies have shown that people who were treated with statins (cholesterol lowering drugs) have been associated with lower dementia risk (Richardson, 2017). Elevated cholesterol levels and high blood pressure continue to be associated with obesity, cardiovascular disease and dementia. In addition, glucose intolerance leading to type 2 diabetes is also associated with these related risk factors and cognitive decline. Therefore, by managing blood cholesterol and glucose levels through healthy diet and exercise, in conjunction with statins or other cholesterol lowering medications, can help decrease dementia risk.

Undoubtedly, the human body naturally begins to decline as a person ages. This decline can easily increase the amount of medication an individual is prescribed. Often it is difficult for older individuals suffering with cognitive impairment to remember medication names, dosages, or the medication’s purpose. These individuals are at a higher risk for medication errors, adverse

A test contrasted three drug diabetes and determined that the new drug from the company, Avandia, succeeded and effected best. The experiment for the drug, Avandia, was funded by GlaxoSmithKline. The company paid 11 authors from the company. 4 of them were employees while 7 of them were academic experts. 4 years later, the research showed that the drug raised the risk of heart attacks. A Cleveland clinic cardiologist named Steven E. Nissen gave one of the earliest warnings about the drug. Scientists estimated 83,000 heart attacks and deaths in their research. The NEJM published 73 articles on the original studies of new drugs while pharmaceutical companies published 60, drug company employees

      Diabetes has been described, by doctors, as a metabolic disease in which the patient has high blood glucose (blood sugar), either because insulin production is inadequate, or because the body 's cells do not respond properly to insulin. The overall management of diabetes for older adults would be the same as management for younger adults. Nutritional management is essential for older adults primarily to control malnutrition and the patient being underweight.  For older adults, diabetes can not only be difficult for their overall health but also can cause financial hardship. I’ll discuss how Medicare and Medicaid help elevate some of the financial burden that

Glitazones are the new class of anti-diabetic drugs that are the first to be able to manage glycaemia goals. Troglitazone was first approved for the market in 1997, but it was withdrawn from the market by 2000. After the withdrawal of troglitazone, rosiglitazone and pioglitazone were introduced in 1999 as potentially safer alternatives. However, currently rosiglitazone is under black box warning for increased risk of cardiovascular disease and pioglitazone is in a nutshell as the drug required more investigation. In this review, the potential ability to predict the adverse drug reactions (ADRs) are examined. If it is possible to predict ADRs, should it be done in the future.