Antimicrobial Applications Of Metal Np Case Study

Kevin Trudeau in his book “Natural cures they don’t want you to know about”, writes that gargling with colloidal silver is a treatment for bacterial infection, viral infection, Candida and even for parasites (2004). The author provides no studies to confirm his recommendations and the efficacy of the treatment on parasites.

Applicability of NCs as wound dressing biomaterials necessarily required the testing of their anti-bacterial potential. Moreover, the effect of AgNPs prepared from different concentrations of precursor salt for NCs development was studied on anti-bacterial activity. Bacteria exposed to NCs showed a zone of inhibition (ZOI), in contrast to bacteria exposed to SC-CNCs only (Fig. 6.10). The measurements of ZOI against each bacterium are presented (Table 6.2). Differences in growth inhibition of different bacteria exposed to NCs were observed, indicating that anti-bacterial action depends on the structural and chemical composition of the bacterial cell surface (Diez-Pascual and Diez-Vicente 2015). NC-1 showed maximum ZOI representing the remarkable inhibitory effect on bacterial growth followed by NC-2 and NC-3, respectively. Pure SC-CNCs were used as a negative control since it has no anti-bacterial activity. Bactericidal activity of NCs could be due to the diffusion of AgNPs from NCs to the culture medium. A large number of small-sized AgNPs present in NC-1 (21 ± 7 nm) showed stronger anti-microbial action in comparison to relatively large sized AgNPs of

Antiseptics are chemical agents that slow or stop the growth of micro-organisms (germs) on external surfaces of the body, that is why they are suitable to use on the skin as they are designed for that pacific reason to stop bacterial growth or any other microorganisms from spreading or causing infection on the skin and external surfaces on the body. Antiseptics should be distinguished from antibiotics that destroy micro-organisms inside the body, and from disinfectants, which destroy micro-organisms found on inanimate (non-living) objects. Antibiotics and disinfectant are designed for other reasons as you can see and contain some different chemical agents that maybe harsh on the human skin so that is why disinfectants and antibiotics may not be suitable on the skin. (http://dermnetnz.org/treatments/antiseptics.html)

In a website, coppertoxic.com, the author states, “ As unbound levels get too high , copper becomes a powerful reactive toxin to both the body and mind, leading to a number of symptoms including brain fog, fatigue and adrenal burnout, depression,...Alzheimer's, schizophrenia, even cancer”(coppertoxic). Copper can be found just about anywhere in the environment, whether it is in the air or in the water, so it is likely for one to come into contact and overdose with copper toxicity to have diseases such as Alzheimer’s. However, copper can aid a person in the prevention of pathogens in hospitals. In an article labeled, “Hospitals could soon be covered in COPPER to ward off diseases: Metal kills deadly bacteria in minutes”, by Victoria Woollaston, the author writes, “During tests, exposure to copper destroyed the virus completely and irreversibly, leading the researchers to conclude that antimicrobial copper surfaces could be used in communal areas to help reduce the spread of respiratory viruses and protect public health” (Victoria Woollaston). With everyday items such as light switches and door handles coated with copper, patients are now safer than ever from respiratory infections like pneumonia. The extermination of viruses is ensured when coming into contact with a coating of antimicrobial copper. In brief, copper is a great aid in the

Platinum is utilized extensively over a range of different items, from catalytic converters in our cars to the pretty rings that we wear on our fingers. It is more importantly used in many treatments that are used on our bodies in cases where we are ill or injured. Medicinal actions are undertaken every single day. The world is dependent on the treatments that the medical field supplies. The claim that metals are the most useful substances poses

The evaluation of a primary quantitative research article includes “Safety and efficacy of a novel silver-impregnated urinary catheter system for preventing catheter-associated bacteriuria: A pilot randomized clinical trial”. This article was featured in American Journal of Infection Control, and was written to present a study that evaluates the safety and efficacy of a type of urinary catheter system which is impregnated with silver. Silver is known to be an antimicrobial agent and has previously been used in catheter manufacturing prior to this study as a silver-coated catheter system with mixed result studies noted for its effectiveness. The manufacturer of the

Lens case contamination is a well-documented occurrence for contact lens wearers despite the efficacy of contact lens disinfectants. Several microorganisms have a propensity to attach to surfaces and may become more tolerant of disinfection upon attachment. Contact lens case is one of the accessories which become contaminated easily and more prone to biofilm formation. Since last few decades the modification of the biomedical devices has attracted attention and the application of the antimicrobial surface is one of them to eliminate microbial contamination. Silver is an established and proven antimicrobial with efficacy against both Gram positive and Gram negative bacteria. In vitro studies evaluating the antimicrobial efficacy of silver-impregnated

Besides Cu(OH)₂, NaNO₃ has also formed in the solution. While heating the solution on the hot plate, the solution begins to turn darker in colour and gradually turns black. There appears to be solid particles in the solution. During the washing and decantation process, any excess NaNO₃ is removed from the solid CuO. The

Copper is a soft metal. Its chemical symbol is “CU”, its latin name is caprum. Copper is an essential in all plants and animals. It helps your body use iron , so a copper deficiency can manifest anemia like symptoms. Copper has antibacterial, germicidal, and antimicrobial properties. Things made of brass, like doorknobs and bullets will rid itself of bacteria within 8 hours.

This conclusion is supported by the minimal usage of of antimicrobial copper surfaces in the intensive care units (ICUs) of

Scientists are fascinated with copper and its ability to be both harmful and beneficial depending on the form that the metal is in. A major issue that excessive copper has produced is copper pollution. The experiment conducted enable copper to be reacted through a series of chemical reactions to explore its ionic and elemental form. The properties of copper salts produced and the characterizes of the reactions were recorded. It also explored the reactivity of copper in the different chemical environments and assisted in making it more clear to find ways to deal with copper

A successful orthopedic implant must meet following criteria: it resembles natural bone, is anti-inflammatory, biocompatible, bearable, has a long lifetime, and supports cell proliferation.1 Since titanium alloy satisfies most of these conditions, it has been widely used as a main element of current implants.2 Another benefit of Ti is the oxide layer yielded from environmental effects, which works as a protective cover against severe situations.1,2 Yet not all the requirements of successful implants have been fulfilled, such as a long lifetime and anti-inflammatory properties. Consequently, an improvement to the existing austenitic stainless steel implant is essential.1 Failure of current implants, shown in Figure 1., is basically attributed to excessive wear and corrosion caused by the structure of its surface with respect to its morphology, composition, and properties.2 Previous studies showed that the localized corrosion of austenitic stainless steel (SS) implants caused by biological attacks result in an ion release of iron, chromium, and nickel, etc. Aggregation of ions around the implant causes severe body reactions such as inflammation. 2-4 Therefore, we must analyze implant biomaterials to find what film coatings can overcome these destructive ionizations.

The topic of biofilm formation and prevention has intrigued researchers for years. Biofilms can lead to serious infections, and are extremely difficult to treat after they have already formed. Due to this difficulty, prevention rather than treatment has become a focal point of biofilm research. Different materials could be tested for potential antimicrobial properties, which, if possessed, could be incorporated into the polymers which compose medical implants. This research could also be used in an industrial context, as biofilms also form on marine engineering systems, cooling or heating water systems, and other industrial environments where they can lead to corrosion and bacterial contamination. If a certain substance is found to have antimicrobial properties which would not damage the tissue surrounding a medical implant or other indwelling medical device, then the substance could potentially be incorporated into the material which makes up the implants or devices in order to prevent harmful biofilms from forming. While there are many methods of preventing biofilms, researchers are still trying to find new ways to treat biofilms which already exist within a host.

Biofilm formation poses a universal complication to all implantable prostheses or devices in the human body. Medical costs rise substantially with biofilm formation and may lead to further life-threatening conditions. Researchers are looking into the anti-bacterial efficacy of different surface-coatings such as metals, polymers, nanoparticle texturing, and composites of each. The method through which bacteria adhere and/or aggregate is different across each surface-coating. While each have shown significance in the reduction of biofilm production in vitro, researchers have yet to perform effective in vivo experiments to confirm durability, adhesion specificity, cytotoxicity, and overall efficacy. It has been supposed that multifaceted “smart” surface-coatings are optimal for inhibiting biofilm production. However, there are still many complications inherent in both the smart-coating’s structure and chemistry that renders it unfeasible as a long-term solution.

The high level of resistance to antimicrobial drugs among bacteria colonizing commercial livestock has raised concerns about the significance to human health of such resistance. The transmissibility of resistant organisms from animal to human hosts has been fundamental to this concern. Kathy Parsonnet and Edward Kass, conducted a study on women who compared Escherichia coli (E. coli) and the rate of contracting the disease. Parsonnet and Kass studied about seven hundred and fifty women from a meat production facility. The average number of antibiotic infused meat handled per shift by each worker was one thousand. In addition to repeated contact by the handling of the meat carcasses, the hands and arms of the women came into frequent