Antipsychotics and Yoga Therapy as an Adjunct Treatment for Schizophrenia

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Antipsychotic Medications and Yoga Therapy as an Adjunct Treatment for Schizophrenia
Sarah Garrabrant
University of South Florida

Schizophrenia is a severe form of mental illness classified in the DSM IV-TR as a Psychotic disorder. It is characterize by broad impairments in cognition that place limitations on recovery (Eack, 2012, p. 235). Antipsychotic drugs are the first line of treatment for Schizophrenic patients, but come with adverse side-effects and many patients are treatment-resistant (Tandon, Nasrallahb, & Keshavanc, 2010). Adjunct treatments that focus on cognition and coping with stress, along with the antipsychotics have shown to be more effective (Sungur, Soyguur, Guuner, Uustuun, Cetin, &
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Typical antipsychotic drugs occupy around 70-90% of D2 receptors at a common dosage (Kleinman, Casanova, & Jaskiw, 1988).
Due to side effects and the nature of the illness, some patients do not keep continuous use of anti psychotic treatment. It has been found that patients with light use of antipsychotics were more likely to be hospitalized than continuous users. The average duration of anti-psychotic use was six months in any single year and compared to individuals with a continuous pattern of anti psychotic treatment, individuals with moderate or light use had odds for hospitalization, 52 or 72% greater (DosReis, Johnson, Steinwachs, Rohde, Skinner, Fahey, & Lehman, 2008). First generation and Second-generation antipsychotics
Researchers wanted to know who was more effective, first generation antipsychotics or second-generation antipsychotics (Kane, 1999). The CATIE trial compares first and second generation antipsychotics, comparing first generation perphenazine with second generation drugs, olanzapine, quetiapine, risperidone, and ziprazidone. Overall, olanzapine did better than other treatments,. What surprised researchers most is that first generation antipsychotic, perphenazine, was similar in effectiveness to three of the four second-generation antipsychotics (Liberman & Stroup, 2010). It has been found that 30% of patients fail to
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