Application Of Magnetic Polymer Nanocomposites

Using the magnetic fields, the scientists can remotely control the nanobots to swim anywhere through the bloodstream. There are many colleges and companies working on developing nanobots. One of these leading companies is Google who is using their Google X research division to make nanobots in condensed into a pill. In the article “Google nanobots: Early warning system for cancer, heart disease inside the body” written for news website RT, it states, “The pills will be able to identify minutes changes in body chemistry and act as an early

Ricardo Morales on the synthesis and characterization of bimetallic magnetic nanoparticles for further application in cancer treatment, I gained the skill sets needed to come up with research ideas and implement them as well as how to resolve issues that arise within any research. My experience as a teaching assistant in organic and general chemistry at the University of La Verne Chemistry Department taught me the importance of lab safety and the joys of connecting what is learned in lecture to lab and helping students make that connection in a lab setting while creating a safe environment. My experience as an Academic Success Center tutor in chemistry course from general chemistry to advance organic chemistry taught me the joys of helping students to truly understand material and not memorize it but have that knowledge become a part of them that they can use whether in a research setting or to explain those concepts to their peers. These experiences in undergrad allowed me to determine that academia was the right fit for me; graduate school will give the skills needed to fulfill this

Using of spinel ferrites nanoparticles in electromagnetic devices such as memories, sensors and data storage in modern information technology applications [1-3] made many researchers all over the world do all efforts for synthesis and development of magnetic nano-particles. These nano-particles possess special magnetic and electrical properties with high

Béalle and collaborators (2014) described the use of superparamagnetic iron oxide nanoparticles (ɣ-Fe2O3) to decorate catanionic vesicles. The vesicles were prepared by using cetyltrimethylammonium chloride and myristic acid and the nanomaterial was synthetized in aqueous alkaline solution by co-precipitation process of FeCl2 and FeCl3. The decoration and incorporation of ɣ-Fe2O3 was carried out by an adsorptive process onto the vesicles structure [7]. Additionally, silica-coated unilamellar surfactant vesicles was prepared by hydrolysis and condensation of silicon alkoxides [8] into organized inorganic material (Dioctadecyldimethylammonium bromide and didodecyldimethylammonium

Synthesis of OA-Fe3O4 NPs: OA-Fe3O4 NPs were prepared following the literature method [36]. For the synthesis of OA-stabilized Fe3O4 NPs, Fe(acac)3 (2 mmol), 1,2-hexadecanediol (10 mmol), oleic acid (5 mmol), oleylamine (6 mmol), and benzyl ether (20 mL) were mixed and magnetically stirred under

Monomer and end capper was synthesized according to known literature procedures [10,11]. The conjugated polymer with two side-chain thiol groups was also synthesized by nickel mediated polymerization method [12,13]. A schematic representation of the synthesis of monomer, end capper, polymer was shown in Scheme 2. 2.2.1. 2,7-Dibromo-9H-fluorene (1) Fluorine (300.8 mmol, 50.0 g) and CHCl3 (450 mL) was taken in the 1 liter round-bottom flask, wrapped with aluminum foil.

Example-2: Nelfinavir-PLGA NPs were prepared by nanoprecipitation method. Drug:polymer weight ratio was varied from 1:1 to 1:5 and particle size, encapsulation efficiency and drug loading were measured. Among the drug:polymer weight ratios prepared, 1:4 ratio was chosen as optimal. NPs found to exhibit sustained drug release up to 24 h and there was a 4.94-fold increase in relative bioavailability compared to pure drug (Venkatesh et al. 2015).

Nanotechnology offers enhanced localisation of treatment delivery to brain diseased sites, including hyperthermia, thermal ablation, as well as chemotherapeutic drug delivery and gene therapy. The procedure may also be monitored with various ionising or non-ionising imaging modalities. Theranostics is an emerging medical field that uses nanoparticles for combining diagnosis and treatment on a single nanoscale platform.

Nanomedicine has been tested to try and fight cancer cells and destroy them by the University of California, Los Angeles(UCLA). The nanomedicine has improved unmodified medicine including targeting efficiency. Nanomedicine delivers a “Double whammy” as it is put by UCLA. Nanomedicine has the strength to possibly overcome some of the most severe diseases especially cancer because once cancer is able to be extinguished the human race could become nearly invulnerable. Cancer is one of the most severe cases of a disease. Cancer could kill thousands and diagnose way more people.

In this study, published in the scientific journal Advanced Materials, Quanyin Hu has created a better way to administer doxorubicin and TRAIL, two anticancer drugs. By using platelets, part of the blood that aids in clotting, to mask the foreign drugs from the body's defense system, these bioengineers caused the drugs to stay in the body for a longer amount of time when compared to the amount of time non-platelet covered anticancer drugs stayed in the body. The results of this experiment showed that platelet covered anticancer drugs stayed in the body longer than the same anticancer drugs surrounded by a nano-gel system. In this experiment, the dependent variable was the amount of time the anticancer drugs stayed in the body of a mouse.

“This work has led many other investigators around the world to study this nanomaterial, but we were one of the first groups to study these nanoparticles in a biomedical context.

To a magnetically stirred solution of 3-methylcyclopentene-1,2-dione 1 (1 mmol) and N-isocyaniminotriphenylphosphorane 3 (1 mmol) in CH2Cl2 (10 mL) was added dropwise a solution of dimethyl acetylenedicarboxylate 2 (1 mol%) in CH2Cl2 (5 mL) at –10◦C over 15 min (Scheme 1).

Drug delivery is the method of transporting a pharmaceutical compound to safely achieve its desired therapeutic effect in the body by using approaches, formulations, technologies, and systems. Today these technologies are nanobiomaterials and the use of nanobiomaterials are unprecedentedly increasing in drug delivery thanks to their significant advances in the diagnosis and treatment of disease. The major goals of using nanomaterials are to reduce toxicity, increase biocompatibility, safety, and specific cell targeting. Otherwise, nanoparticle-based vehicles in drug delivery is an important technology because of their small-sizes, easy penetration through cells, increasing cellular uptake, and capacity to carry large amounts of drugs, thus

In the past several years, various CLRP strategies have been developed, among which reversible addition-fragmentation chain transfer (RAFT) is an ideal choice not only owing to its good compatibility to a broad range of monomers and mild reaction conditions, but also because of its versatility in producing well-defined complex architecture. Magnetic molecularly imprinted polymers (MMIPs) prepared by the surface-initiated RAFT polymerization are very popular among researchers, because of the formation of a well-defined MIP layer on magnetic nanoparticles. He et al. developed well-defined nanostructured surface-imprinted polymers by RAFT polymerization for highly selective magnetic separation of fluoroquinolones in human urine. Previously, we introduced a general method to prepare a uniform layer of MIPs with a diameter of ∼60 nm on the surface of Fe3O4@SiO2 nanoparticles via RAFT polymerization for the Sudan dyes residue analysis of real samples. Nevertheless, the relatively slow polymerization rates and extended polymerization times have been problematic for achieving a consistent polymer composition. Thus, improving RAFT strategy aiming to prepare a layer of MIP on the magnetic nanoparticles with high polymerization rates

This technology is also being looked into for creating diagnostics to identify abnormal cells in the body. Currently, none of this technology has been applied to clinics as there is not enough data to support the safety of nanoparticles in the body. However, experiments and further development are still occurring to allow for its use in the future.