Assess The Difference Between Cystic Fibrosis And Homozygote

Homozygous: Refers to expressing the same alleles for a particular trait. If black was dominant for the above chicken, and the alleles were coded for by B, if it was homozygous, the chicken’s genotype would be BB.

Cystic fibrosis is a continuous, genetic disease that causes persistent lung infections and limits the ability to breathe over a period of time (Cystic Fibrosis Foundation). When an individual has cystic fibrosis, they tend to have lots of various lung problems. The overall cause of their lung problems is related to basic problems with diffusion and osmosis in the large airways of the lungs. The non-working cystic fibrosis proteins do not allow salt or water to enter the air space, resulting in the mucus layer to be extremely concentrated and very sticky. When you focus on individuals without cystic fibrosis, you can see that they have a small layer of salt water in the big airways of their lungs. This layer of salt water lies underneath

They are also accompanied by many medicines and other treatments to help them with the comfort of cystic fibrosis.

Air the vital ingredient of life. Without air there will be no oxygen. Now imagine having lungs that will not fill correctly. People with cystic fibrosis (CF) live with this everyday of their life.

Cystic fibrosis (CF) is a lethal autosomal recessive disorder with a clinical incidence of 1 in every 3500 newborns1. Currently, over 4000 Canadians have CF, with 60% being adults2. In the past, CF was considered a fatal disease with a life expectancy of less than two years, however, advances in enzymatic and antibiotic therapy have greatly improved the life expectancy of patients afflicted with CF3. Currently, the median age of Canadian CF patients is 50 years2.

Monozygotic twins: Monozygotic twins are also known as identical twins. These twins start their life as one egg which is fertilized by one sperm and latter splits into two eggs much earlier in the gestational period. These are very rare and have no link to heredity. But studies reveal that only one of four conceptions of twins is identical. Therefore, it seems likely that any differences between twins will have to be caused by environment rather than by genetics.

Cystic Fibrosis is a disorder where the exocrine glands secrete abnormally thick mucus, leading to obstruction of the pancreas and chronic infections of the lungs, which usually cause death in childhood or early adulthood. Some mildly affected patients may survive longer. Doctors can diagnose the disease by testing the patients perspiration because people with Cystic Fibrosis have high amounts of salt in their perspiration. Those with respiratory infections are treated with antibiotics, with aerosols that relieve constriction of the airways and liquefy the thick mucus, and by physical therapy to help patients cough up the obstructing secretions. Patients with pancreatic insufficiency can take pancreatic enzymes with meals.

Contact with germs is a concern for people with cystic fibrosis. Sticky mucus build up in the lung allow these germs to thrive and multiple (About Cystic Fibrosis, 2013). Pseudomonas aeruginosa is a gram-negative bacteria very commonly carried around by healthy individuals without any symptoms. But for people who are ill and have weak immune systems, this bacteria can cause a deadly infection. Infection is hard to treat because Pseudomonas aeruginosa can resist many antibiotics. Pseudomonas aeruginosa is spread easily in hospitals by health care professionals and uncleansed medical equipment. This serious infection can cause pneumonia in the lungs and cause septic shock if released into the blood stream (CDC 2014). Therefore, the exposure to

Cystic Fibrosis is a genetic disease that causes the body’s lungs to generate a different type of mucus than a non-infected body would. The contaminated lungs will produce mucus that is thick and adhesive which clogs the lungs and leads to an unpleasant and abhorrent lung infection. CF also interferes with the pancreas, disallowing the digestive enzymes from breaking down and absorbing food in the intestine. This can result in low nutrition, feeble growth, excessive sweat production, difficulties in breathing, and sometimes lung disease. When producing extra sweat and mucus, the body loses salt. If too much salt is lost, it can cause abnormal heart rhythms, disturbance of minerals in the blood, and perhaps, shock.

Like the world around us the medical field is always changing. It is always pushing forward, trying to understand mysteries of the human body that have boggled researchers for decades. What confuses scientists more, are the organisms or conditions that create these abnormalities that can send the human body into a downward spiral. Disease is something that has affected human civilization since the dawn of time. It can either be chronic or acute, but in either case it has the potential to bring havoc to the human body systems that can lead to devastating consequences. Generally there are two main types of diseases, ones caused by invading pathogens and those which are hereditary. One hereditary disease that can be particularly tragic is

The average life span of a person with Cystic Fibrosis is 25-30 years of age. Although the more traditional treatments of this disease are adequate, is there something else that could be even better? Gene therapy is fast becoming one of the more studied aspects of genetics today. Let's take a look at some details of Cystic Fibrosis and gene therapy.

Imagine drowning, lungs filling with water that swallows the air and suffocates those caught in it. Now, imagine drowning in a hospital bed surrounded by doctors and family members who can only stand by and watch the inevitable. This is the fate of a person with Cystic Fibrosis. Cystic Fibrosis is a disease that forces a person to drown in mucus that fills their lungs while it wreaks havoc on the body. This chronic disease causes devastating health problems, has no cure, and forces patients to endure painful temporary treatments. Taking daily medications, maintaining a social life, and staying moderately healthy are a constant struggle for people with Cystic Fibrosis.

Cystic Fibrosis (CF) is an autosomal recessive gene that causes a wide range of symptoms because there are over 1,000 changes or mutations that can occur within the cystic fibrosis transmembrane receptor (CFTR) protein. The CFTR protein is generally a chloride ion chain “regulated by cyclic adenosine monophosphate and therefore can act as a regulator of other electrolyte channels”(Grossman, S., & Grossman, L. 2005, p. 46). Typically this protein allows chloride ions to exit mucus-producing cells allowing water to flow in and thin the mucus. However, if the CFTR protein has been mutated, such as in cystic fibrosis, chloride ions cannot exit. This causes the mucus to thicken, become sticky, and obstruct the various channels it passes through. This build up of mucus also prevents bacteria from being cleaned from cells thoroughly increasing the patients risk for infections (Grossman, S., & Grossman, L. 2005). However, the severity of CF depends on whether the patients have complete or partial loss of the CFTR gene. If the person has the classic form of CF abnormalities of CFTR will commonly affect “…the respiratory, gastrointestinal, endocrine and metabolic, and genitourinary systems”(Schram, C. 2012). However, if people have atypical forms of CF their genetic disorder may only affect one of the organ systems and may not be found until the patient develops symptoms in their late childhood, early adolescence, or adulthood

Cystic fibrosis is an inherited disease that ultimately leads to death. It affects every racial group worldwide, but its prevalence varies from country to country. In those with cystic fibrosis, the lungs and digestive system are primarily affected by the disease. With the new developments in treatment and management, the 50 percent survival rate from the 1970’s has greatly improved, allowing patients to continue to live their lives longer than ever expected in the past. The new developments in prevention of exacerbations, therapy drugs and methods to preserve lung function have done great things to help patients extend their lives. Education is another important aspect of treating cystic fibrosis. For example, more the

Some of the other risk factors are linked to both porcine and human cysticercosis. According to Bhutta et al (2012) ,Garrett et al (2015) and Assana et al (2010), low level hygiene environment such as dirty contaminated soil and lack of latrine may rise opportunities to access Taeniid ova because dirty soil can increase the possibility of exposure to taeniid ova for both human and pig and taeniid ova can flow to water resource like wells in rainy season.