Atherosclerosis Research Paper

Coronary artery disease is a disorder affecting the blood vessels of the heart, generally in the form of atherosclerosis. Atherosclerosis literally means “fatty harden mush”. This is formed from the

Sometimes atherosclerosis occurs in the carotid arteries, especially at the bifurcation or the point where the common carotid divides into the internal and external carotids. Atherosclerosis means that a potentially dangerous plaque has formed on the artery wall. Plaque is a sticky material made of fat and calcium which hardens the arteries and can block the flow of blood. This narrowing is sometimes called a carotid artery stenosis, meaning that the carotid artery has narrowed significantly.

Atherosclerosis is a type of cardiovascular disease that affects the arteries. I chose this disease because a few years ago my dad was having the beginning symptoms of a heart attack. We didn’t know what was wrong with him, but we thought he had acid reflux. Fortunately, we got him to go to the emergency room before anything bad happened. My dad had atherosclerosis in several of his arteries for his heart. Our insurance only covers the arteries that have so much blockage, so this is not solved forever. Thus, I chose this disease to inform and learn more about it.

Arteries carry blood from the heart to the rest of the body. A thin layer of cells allows blood to flow easily and it’s called the endothelium. Atherosclerosis begins when the endothelium becomes damaged allowing bad cholesterol to build up in the artery wall. The body sends white blood cells to clean up the bad cholesterol but sometimes the cells get stuck at the affected site. Over time plaque can accumulate, made up of cholesterol, macrophages, calcium, and other substances from the blood. Can be fatal if not treated.

Atherosclerosis begins when an accumulation of white blood cells form plaque on the artery wall. These plaques are made up of both live and dead cell, including cholesterol and triglycerides, this can create an inflammatory response in the tissue of the artery wall. These atherosclerosis plaques can be divided into two categories, stable and vulnerable. The stable plaques tend to be asymptomatic and are characterized by smooth muscle cells and have a stronger cell matrix. The second category is vulnerable plaques; these tend to be unstable and have higher levels of macrophages and foam cells. The extracellular matrix creates breaks in the fibrous cap and can lead to ruptures.

Disease of the arteries called atherosclerosis is medical condition characterized with accumulation of fatty material on the internal walls of the blood vessels that has impact on the blood flow. Medical experts warn that this medical condition is quite severe as it may lead to cardiac arrest, brain hemorrhages or even death.

Atherosclerosis: (Hardening & Narrowing of arteries): It is the cause of coronary artery disease in which the walls of the coronary arteries thicken due to accumulation of plaque in the blood vessels.

Coronary heart disease occurs due to the built up of plaque within coronary arteries. Coronary arteries play an important role in supply the oxygenated blood to cardiac muscles in the heart. The oxygenated blood supplies the cardiac muscles with oxygen and nutrients, so that the muscles are able to continue contract and relax and prevent them from tetanizing. Plaque is a waxy substance that blocks the coronary arteries, thus reducing rate of blood flow to heart muscle. This condition may lead to ineffective functioning of heart due to lack of nutrients and oxygen. To make the matter worse, accumulated plaque becomes atherosclerosis where this substance grows and eventually cause damaging effects which is

Coronary heart disease is when the arteries that supply your heart and other parts of your body with oxygen-rich blood are narrowed by the gradual build-up of fatty materials known as cholesterol within the artery walls. This condition is referred to as atherosclerosis and the fatty material that is deposited in the arteries is called an atheroma. These fatty deposits that line the artery walls can lead to the clogging of arteries which might result in blood clotting. This, in turn, can lead to a heart attack if one of the arteries leading to the heart is clogged as the blood flow of oxygen-rich blood is cut off to the heart causing the cells in the heart to die from the lack of oxygen.

The definition of cardiovascular disease as stated by the British Heart Foundation is as follows, “cardiovascular disease includes all diseases of the heart and circulation, including coronary heart disease (i.e. angina, heart attack), heart failure, congenital heart disease, and stroke. It is also known as heart and circulatory disease.” Although there are numerous subtypes of cardiovascular disease they are all interrelated by a common setback. Atherosclerosis, which is the build-up of a fatty streak inside of the arterial walls, is the mutual element that links all forms of cardiovascular disease together. The build-up of fatty plaque inside of the artery walls can have a number of negative effects on the human body. For example, angina occurs when the narrowing of the arteries due to the build-up of plaque inhibits a sufficient amount of oxygen-rich blood to pass through to the heart. Similarly, a heart attack occurs when part of the fatty plaque breaks away or ruptures and clots the coronary arteries, drastically reducing blood-supply to the heart. Both of these conditions lead to various side effects that can significantly lower ones quality of life or even result in death.

The cause of coronary artery disease is atherosclerosis, hardening of the arteries. This occurs when fat, cholesterol, and other substances build up on the walls of arteries and form hard structures called plaque. Over time, this plaque can block the arteries and cause problems throughout the entire body (Newton,

Cardiovascular disease (CVD) is a class of disorders that involves the heart and blood vessels. A major contributor to CVD is atherosclerosis. The complications of atherosclerosis are the most common cause of death in Western countries. Rupture of atherosclerotic plaques lead to dangerous clinical complications such as myocardial infarction and stroke. Epidemiological studies identified many lifestyle factors that increase the risk of developing atherosclerosis. Mostly older or middle-aged adults are affected by the disease, although the process already starts in early life. The onset of atherosclerosis mostly starts with endothelial dysfunction. Different cellular elements of the arterial wall are involved, such as monocytes, macrophages,

When the coronary arteries are no longer working, this is call coronary artery disease. The process by which causes the coronary arteries to stop the blood and oxygen flow to the heart is call atherosclerosis. What this process does is collect a ton of unwanted fat and cholesterol known as plaques and stack the unwanted fats and cholesterol alongside the coronary artery walls and with time it will stack up to cause a complete clog, or blood clot, in the coronary arteries restricting blood and oxygen flow to the heart this is known as coronary thrombosis. Once the blood and oxygen flow is restricted, cardiovascular then takes place which will result in heart attack or more commonly known as, the leading cause of death.

CAD is a chronic process that takes a life time to develop and manifest itself. It occurs when the coronary artery that supplies the heart with blood, oxygen and nutrients becomes narrow or blocked by fatty plaques. Atherosclerosis which is the buildup of cholesterols deposits within intima of the arteries are the common causes of CAD. Inflammation due to an injury to endothelium cell plays a vital role in the formation of atherosclerosis. Typically, the inner lining of the vessel wall (Endothelium) does not coagulate with thrombocytes, white blood cells or other coagulation factors. However, when the endothelium gets injured due to smoking, high blood pressure, hyperlipidemia, infection causing inflammatory system will respond to the injured

Atherosclerosis (ath"er-o-skleh-RO'sis) comes from the Greek words athero (meaning gruel or paste) and sclerosis (hardness). It's the name of the process in which deposits of fatty substances, cholesterol, cellular waste products, calcium and other substances build up in the inner lining of an artery. This buildup is called plaque. It usually affects large and medium-sized arteries. Some hardening of arteries often occurs