Atherosclerotic Disease Research Paper

Atherosclerosis (ath"er-o-skleh-RO'sis) comes from the Greek words athero (meaning gruel or paste) and sclerosis (hardness). It's the name of the process in which deposits of fatty substances, cholesterol, cellular waste products, calcium and other substances build up in the inner lining of an artery. This buildup is called plaque. It usually affects large and medium-sized arteries. Some

While most people have heard of strokes, many don't know the importance of your carotid artery in causing a stroke. It's important for everyone to understand the signs of carotid artery disease and how to reduce the risk of it leading to a stroke.

What is Atherosclerosis Disease?Well Atherosclerosis is a disease in which plaque builds up inside your arteries.Arteries are blood vessels that carry oxygen-rich blood to your heart and other parts of your body.The Atherosclerosis Disease is caused by high blood pressure,smoking,or high cholesterol.Did you know that about 360,000 people will die from the Atherosclerosis disease each year. Nikolai N. Anichkov was the one who discovered the Atherosclerosis disease.Atherosclerosis was discovered in 1964 by Anichkov.

There are multiple things that can cause atherosclerosis; being a smoker can cause damage to the walls of the arteries, platelets then clump together to try to repair it this will cause the arteries to become narrow. Smoking can also prevent the blood from being able to carry oxygen around the body which increases the chances of blood clotting. Having a higher fat diet and high cholesterol can cause atherosclerosis because if you eat too high fatty food diet it can cause you to have high levels of low-density lipoprotein, this carries the cholesterol from your liver to the cells that needs it, if there is too much cholesterol the excess can build up in the artery walls which leads to fatty deposits and over time this can partly or completely block the blood supply. Lack of exercise and being overweight or obese will not directly affect your chances of developing atherosclerosis, but contributes to other things that do raise the chances. They are likely to have high blood pressure, they are likely to have high cholesterol because of their diet and more chances of developing type 2 diabetes. Having type 1 or type 2 diabetes causes excess glucose in your blood can damage the walls in the

Atherosclerosis is the hardening and narrowing of arteries, which quietly and gradually blocks arteries, putting blood flow at risk, according to WebMD. Plaque gathers up in the arteries and is composed of fatty substances, calcium, fibrin, cholesterol, and waste products from cells. It can completely or partly cut off the blood in the artery. One of two things can happen in the area where the plaque is building up in the artery: a piece of the plaque may break off or a blood clot may form on the plaque's surface, according to the American Heart Association. Atherosclerosis is a kind of arteriosclerosis, which is simply the thickening and hardening of arteries. It is typically the agent of strokes, peripheral vascular disease, and heart attacks,

Atherosclerosis is a reduction of the arteries triggered by a buildup of plaque. It is also called arteriosclerosis or hardening of the arteries. Arteries are the blood vessels that transport oxygen and nutrients from the heart to the rest of the body. As the body gets older, fat and cholesterol can collect in the arteries and form plaque. The buildup of plaque makes it difficult for blood to flow through the arteries. This buildup may transpire in any artery in the body and can result in a shortage of blood and oxygen in various tissues of the body. Pieces of plaque can also break off, causing a blood clot. If left untreated, atherosclerosis can lead to heart attack, stroke, and heart failure. Atherosclerosis is a fairly common problem associated with aging. According to the University of Maryland

Atherosclerosis is a disease in which fatty materials and plaque buildup on the inner lining of arteries. Arteries are blood vessels which carry rich blood to the heart and throughout the body. They’re lined by the endothelium, a thin layer of cells. The endothelium keeps blood flowing by keeping the inside of arteries smooth. However, when Atherosclerosis starts due to high blood pressure, smoking, or high cholesterol, it damages the endothelium. Atherosclerosis tends to happen throughout the body and arises when people grow older. This disease is mainly due to the deposition of fatty materials i.e., cholesterol, calcium and other substances found in the blood. The buildup of fat then hardens causing narrowing of the arteries. This

One source of great mortality and morbidity in Europe and North America is the cardiovascular disease, Atherosclerosis. It is recognized as a chronic inflammatory disease of the intermediate and large arteries characterized by the thickening of the arterial wall and is the primary cause of coronary and cerebrovascular heart disease (Wilson, 2005). It accounts for 4.35 million deaths in Europe and 35% death in the UK each year. Mortality rate are generally higher in men than pre-menopausal woman. Past the menopause, a woman’s risk is similar to a man’s (George and Johnston, 2010). Clinical trials have confirmed that lipid accumulation, endothelial dysfunction, cell proliferation, inflammation matrix alteration and foam cell formation are

You lounge on your couch and watch your favorite sitcom on the television. An ice cream commercial comes up, and all of a sudden you feel like having some ice cream too. You reach for a spoonful of ice cream in your freezer, but find yourself finishing half the tub in the next moment. Coronary heart disease has become a worldwide epidemic; with its major causative factors including diet and lifestyle. A statistic provided by the Centers for Disease Control and Prevention (CDC) stated that in the United States, about 610,000 people die of heart disease annually– that’s 1 in every 4 deaths. More than half that amount of death is caused by coronary heart disease.

An inherited killer, Cardiovascular diseases are quite devastating. From medical bills to lost sleep cardiovascular disease can destroy many families. In today's world, there is a rise in the US population adopting unhealthy lifestyles that lead to cardiovascular disease. Cardiovascular diseases are also known as heart diseases. This is a class of diseases that affect the heart and the blood vessels. The blood vessels are the arteries, capillaries, and the veins. The various diseases that fall under the term cardiovascular disease include coronary artery disease, heart attack, heart failure, high blood pressure and stroke. The more common form of cardiovascular disease is Coronary Heart Disease or Coronary Artery Disease. The Coronary Artery

Atherosclerosis is a type of cardiovascular disease that affects the arteries. I chose this disease because a few years ago my dad was having the beginning symptoms of a heart attack. We didn’t know what was wrong with him, but we thought he had acid reflux. Fortunately, we got him to go to the emergency room before anything bad happened. My dad had atherosclerosis in several of his arteries for his heart. Our insurance only covers the arteries that have so much blockage, so this is not solved forever. Thus, I chose this disease to inform and learn more about it.

The frequent consumption of fast food disturbs the levels of cholesterol and fat that the body cannot process and results in atherosclerosis or clotting of the blood. The accumulation of fat and cholesterol in the body not only results in atherosclerosis but also increases the risk of blood clotting (Miller). Blood clotting is also a primary cause of cardiovascular diseases apart from atherosclerosis because it escalates the resistance of blood flowing through the veins and arteries. Fast food consumption is not only one of the leading causes of obesity and cardiovascular diseases but also leads to several other health disorders, including diabetes and hypertension.

Although it was believed for a long time that second-hand smoke only affects smokers, since the early 1980s it has been known that non-smoking family members of smokers have twice the risk of experiencing heart attacks than those in non-smoking households. Consequently, people living and working in environments that contain second-hand smoke suffer coronary heart diseases (CHD) due to the toxic substances of tobacco smoke.

Two experimental systems will be used to determine if Mad1 overexpression promotes atherosclerosis. Both sets of experiments are routinely performed in the laboratory of Dr. Lian-Wang Guo and will be performed in collaboration with him. First, a mechanical injury model will be used to determine if elevated levels of Mad1 promote intimal hyperplasia. To generate the mechanical injury, mice will be anesthetized and undergo bilateral endoluminal injury to the femoral artery by passing a 0.25 mm diameter angioplasty guidewire 3 times 56. 1 and 3 days post-injury, protein expression will be determined by immunoblot. HA and Mad1 antibodies will be used to measure expression and localization of endogenous and inducible Mad1. PCNA will be used as a marker of VSMC proliferation.

The damage caused by the constant pressure that untreated hypertension exerts on artery walls can lead to atherosclerosis the severe narrowing and hardening of the arteries. Arteries hardened and narrowed by atherosclerotic plaques (fatty build up) may not be able to supply enough blood to the body’s organs. If the organs don’t get enough oxygen and nutrients, they can’t work properly (Stevens et al. 2012).