Atherosclerotic Plaque Formation

Another word used to describe a heart attack is myocardial infarction, cardiac infarction and coronary thrombosis. A heart attack is the death of a part of the heart caused by the loss of blood supply. The blood supply is usually gone due to a coronary artery being blocked by a blood clot. When a part of a heart artery breaks a blood clot forms around the piece. This blood clot can block the blood flow through the heart muscle. When the heart muscle needs oxygen it is called ischemia. When damage of a part of the heart muscle happens it’s called a heart attack. During a heart attack damage occurs depending on the size of the area blocked by the blood clot as well as the time between the actual heart attack and the treatment. Even though the heart may be hurt, the rest of the organs work with no problems. However, it will not pump as much blood as it used to in order to supply the same amount of blood to all of the parts of the body.

Atherosclerosis (ath"er-o-skleh-RO'sis) comes from the Greek words athero (meaning gruel or paste) and sclerosis (hardness). It's the name of the process in which deposits of fatty substances, cholesterol, cellular waste products, calcium and other substances build up in the inner lining of an artery. This buildup is called plaque. It usually affects large and medium-sized arteries. Some

What is cardiac arrest? “According to the Centers for Disease Control (CDC), sudden cardiac arrest is when the heart suddenly stops beating, resulting in no blood flow to the brain and other vital organs.” .This occurs instantly leading to unexpected death. People tend to confuse a heart attack and cardiac arrest with one another (pause)... a heart attack can lead to cardiac arrest, but they are completely different. What is a heart attack? A heart attack is caused from a blockage of blood flow to the heart muscles. (pause)

A heart attack occurs when an artery that supplies blood to the heart becomes blocked. The loss of oxygen and nutrients damage the heart's muscle tissue, causing the remaining healthy tissue to pump even harder to keep up.

lives. A simple definition of a heart attack is a sudden failure of the heart

“When I was out those 20 minutes, I saw a man who had long ruffled hair and kind of a thick beard, and it didn’t take me long to realise that that was Jesus,” Zack told CBS DFW.Sudden cardiac arrest (SCA) is not the same as a heart attack. A heart attack occurs if blood flow to part of the heart muscle is blocked. During a heart attack, the heart usually doesn’t suddenly stop beating.

Many illness or diseases are known as silent killers because there are no signs or only vague signs of symptoms. These silent killers are deadly; in fact, they gradually consume a person in the early stages. One of those silent killers is High Blood Pressure also known as hypertension.

Myocardial Infarction (MI) is more commonly referred as the heart attack. This typically occurs due to an interruption, albeit partial to some part of the heart, which causes the cells in the heart to die and as a result sends

Heart muscle died as a results of myocardial infarction (MI) which the main coronary arteries was blocked, and large part of the heart muscle was affected due to cellular death from lack of blood flow and oxygen. Cell death is one of the most crucial events in the evolution of MI. A heart attack or MI is usually caused by a blood clot (thrombosis) that forms inside a coronary artery, or one of its branches, which suddenly blocks and stops the blood flowing to a part of the heart muscle. When the blood flow is interrupted necrosis occurs ( McCance & Huether, 2014).

     Sudden death occurs due to cardiac arrest. Cardiac arrest may be the first symptom of coronary artery disease and may occur without any symptoms or warning signs. Other causes of sudden death include drowning, suffocation, electrocution, drug overdose, trauma (such as automobile accidents), and stroke. Drowning, suffocation, and drug overdose usually cause respiratory arrest which in turn cause cardiac arrest. Trauma may cause sudden death by severe injury to the heart and brain, or by severe blood loss. Stroke causes damage to the brain which can cause respiratory arrest and/or cardiac arrest.

Sudden cardiac arrest is a condition in which the heart suddenly and unexpectedly stops beating. When this occurs the blood flow stops to the brain and vital organs. Sudden cardiac arrest is not the same as a heart attack or myocardial infarction. A heart attack is when the blood flow to part of the heart is blocked.

A heart attack, also known as a myocardial infarction, usually occurs when a blood clot forms inside a coronary artery at the site of an atherosclerotic plaque. The blood clot severely limits or completely cuts off blood flow to part of the heart. In a small percentage of cases, blood flow is cut off when the muscles in the artery wall contract suddenly, constricting the artery. This constriction, called vasospasm, can occur in an artery that is only slightly narrowed by atherosclerosis or even in a healthy artery. Regardless of the cause of a heart attack, the oxygen deprivation is so severe and prolonged that heart muscle cells begin to die for lack of oxygen. About 1.1 million people in the United States have a heart attack every year;

Many of the vaso-protective function of endothelium is provide by the Nitric Oxide(NO)20.Endothelium damaged by turbulent or non-laminar blood causes decreased production of NO.Such kind of blood flow also stimulates endothelial cells to produce adhesion molecules, which recruit and bind inflammatory cells. Hypercholesterolemia seems to inactivate the normal function of NO. The net effect is endothelial binding of monocytes and T cells, migration of these cells to the subendothelial space, and initiation of a local vascular inflammatory response. Lipids in the blood, particularly low-density lipoprotein (LDL) and very-low-density lipoprotein (VLDL), also bind to endothelial cells. 18Firstly LDL is transported across the healthy intima and become trapped in intima of a vessel wall.It undergoes oxidative modification and then oxidized LDL(OxLDL) is formed5.OxLDL is mighty inducer of inflammatory molecules.It adds up to the inflamotory signaling by endothelium that activates chemotactic substances, growth factors that attracts monocytes to vessel wall21Eventually OxLDL transforms monocytes into macrophages which makes the Forms cells, which are the hallmark of atherosclerosis. Oxidized LDL impair the signal transduction between endothelial cell surface receptors and NO production, inhibit NO synthase activity and inactivates NO realese from endothelial cells.22.Once the endothelium is impaired, oxidized LDL is stored in vascular endothelium and by the process of series of mechanism, foam cells are formed and then eventually fatty plaque that occludes the vessel along with the decreased amount of NO which decreases the ability of the vessel to dilate. As the plaque grows arterial wall narrowing and thickening occurs5. This plaque and narrowing of vessel results in decreased blood flow

Heart attacks , we have all seen them played out on our favorite drama shows but these shows do not address the real severity of an actual heart attack despite the great acting skills portrayed . A heart attack can also be known as a myocardial infarction (MI), acute myocardial infarction (AMI), acute coronary syndrome, coronary thrombosis, or coronary occlusion, either way it is not good news. Over 1.2 million people in American have heart attacks with many of them resulting in death (Heart attack, 2011). A heart attack is a serious life threatening condition that needs to be treated quickly.

your heart beats it pumps blood throughout your body to give it the energy and