Once upon a time in a town lived the townspeople. The town was not very big, it was made up of 3 families. These families lived separate from each other, but in order to survive all the families worked together to provide and make food for the town to eat. This food was called ATP.
One family, glycolysis, lived in the outskirts of the town, an area known as the cytoplasm. This area is not only home to them but you can find 2 phosphates, 2 ADPs, and 1 glucose growing at a time.Their job was to take glucose, which was found near their house, and break the 6 carbon molecule into two 3 carbon molecules. This was hard work and required the family to be well fed, they ate two ATPs knowing that they would be producing more. Phosphate that’s
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Creating CO2, this cleaving of carbons happens 3 times creating 3 CO2 for each citric acid. The krebs also turn some NAD+ into NADH. They do this 3 times. Also the Krebs take ADP and turn it into ATP. THey turn FAD into FADH2 as well. After all of this is done the Krebs are left with what they started again, one Oxaloacetic. Since two Citric acids are made because of the two pyruvates from the Glycolysis family, the family does this process twice. They also end up making a total of 6 NADHs, 2 ATPs, 2 FADH2s. The Krebs also receive the 2 ATPs, 2 NADHs from the Glycolysis family, also they have two NADHs from the pyruvate processing. So in total The Krebs family has a total of 4 ATPs, 10 NADHs, and 2 FADH2. They send this all to the third family, the Electron Transport Chain, (ETC).
The ETC lives on the edge of the Inner mitochondrial space on the border called Inner mitochondrial membrane. On one side of the house is the inner mitochondrial space on the other side is called the space between the membranes. The NADHs enter the house and electrons are taken and the provide energy for a pump to pump protons from the NADHs outside into the Space between the membrane. The family also does the same thing with The FADH2. THe NADHs become NAD+ again and the FADH2 become FAD+ as well. The electrons used to power the pumps move down the chain of pumps, being pulled by Oxygen at the
Aerobic respiration happens only when oxygen is presented in the cell. Aerobic respiration starts with pyruvate crossing into the mitochondria. When it passes through, a Coenzyme A will attach to it producing Acetyl CoA, CO2, and NADH. Acetyl CoA will enter into the Krebs cycle. In the Krebs cycle Acetyl CoA will bound with Oxaloacetic Acid (OAA), a four carbon molecule, producing the six carbon molecule, Citric Acid. Citric Acid will reorganize into Isocitrate. This will lose a CO2 and make a NADH turning itself into alpha ketoglutarate, a five carbon molecule. Alpha ketoglutarate will turn into an unstable four carbon molecule, which attaches to CoA making succinyl CoA. During that process a CO2 and NADH is made. An ATP is made when CoA leaves and creates Succinate. This molecule is turned into Fumarate, creating two FADH2 in the process. Then Fumarate is turned into Malate then into OAA making two NADH. Only two ATP is produced in Krebs cycle but the resulting NADHs and FADH2s are passed through an electron transport chain and ATP synthase. When the molecules passes through that cycle a total of 28 ATP molecules are produced. In all aerobic respiration produces 32 ATP and waste products of H2O and
The citric acid cycle, also called the Krebs cycle or the tricarboxylic acid, TCA, cycle, a series of chemical reactions that generates energy from the oxidation of acetate into chemical energy and carbon dioxide in the form of ATP. It also provides NADH, which is a reducing agent that is very common in biochemical reactions. This cycle is constantly supplied with new carbon. This comes in from acetyl-CoA, which starts the entire process of the citric acid cycle. The first step of the citric acid cycle is the aldol condensation of oxaloacetate and acetyl-CoA and water with the enzyme citrate synthase in order to form citrate and CoA-SH. The next step is the dehydration of citrate with the enzyme aconitase in order to form cis-aconitate and water. Then comes the hydration of cis-Aconitate and water with the enzyme aconitase in order to form isocitrate. The next is the oxidation of isocitrate and NAD+ with the enzyme isocitrate dehydrogenase in order to form oxalosuccinate and NADH and H+. Then, there is the decarboxylation of oxalosuccinate with the enzyme isocitrate dehydrogenase in order to form alpha-ketoglutarate and carbon dioxide. Next, there is the oxidative decarboxylation of alpha-ketoglutarate and NAD+ and CoA-SH with the enzyme alpha-ketoglutarate dehydrogenase in order to form succinyl-CoA and NADH and H+ and carbon dioxide. The next step is the substrate-level phosphorylation of succinyl-CoA and GDP and Pi with the enzyme succinyl-CoA synthetase in order to form succinate and CoA-SH and GTP. Then, there is the oxidation of succinate and ubiquinone with the enzyme succinate dehydrogenase in order to form fumarate and ubiquinol. Next, is the hydration of fumarate and water with the enzyme fumarase in order to form L-malate. The final step is the oxidation of L-malate and NAD+ with the enzyme malate dehydrogenase in order to form oxaloacetate and NADH and H+. Two cycles are required for every single glucose molecule because two acetyl Co-A molecules
The acetyl group (2C) of acetyl CoA combines with oxaloacetate (4C), this produces citrate (6C) which then goes through a sequence of electron yielding oxidation reactions, during which two CO2 molecules are released, restoring oxaloacetate. This is then used in the next cycle by re binding to another acetyl group. In the process the elections produced are transferred to electron carriers and are later used by the electron transport chains to drive proton pumps to generate ATP. The function of the citric acid cycle is the harvesting of high-energy electrons from carbon fuels.
The oxidation number of an atom of any free element is ZERO. Means to say there is only one kind of atom present, no charge.
Table 2: Consists of color extract taken from a red cabbage for a natural indicator. The pH reading that was measured by using the pH meter and the result of the pH reading to determine whether the solution was acidic or basic.
2. (5 pts) List and explain the names and affiliations of the various characters/stakeholders in this story – I’m looking for us to use the story to map out the complexities that are generally associated with solving public health puzzles – the stakeholders you list and explain here should apply to many of the cases we consider going forward.
The third and final step in cellular respiration is the electron transport chain which takes place in the inner mitochondrion membrane. This process uses the high-energy electrons from the Krebs cycle to convert ADP into ATP. These high-energy electrons are first passed along the electron transport chain. Every time 2 electrons travel down this chain, their energy is used to transport hydrogen ions (H+) across the membrane. These H+ ions escape through channels into an ATP synthase. This causes it to spin, transforming the ADP into ATP. On average, each pair of high-energy electrons that moves down the electron
As the electron moves down the chain, protons leave the Matrix, causing a gradient. Protons reenter the matrix in a process called ATP Synthesis. At the end of the electron transport chain, oxygen accepts electrons and takes up protons to form
This is when one molecule of glucose is split into two molecules of pyruvate - a 3C. Glycolysis produces reduced NAD, pyruvate and has a net gain of 2 ATP, originally, 4 ATP molecules are produced but 2 are used up during glycolysis. showing the transfer of energy within an organism as the ATP is a source of energy for the biological process taking place. In the link reaction, pyruvate is converted into acetyl CoA, it is decarboxylated, releasing carbon dioxide as a waste product. Pyruvate is then oxidised, forming acetate, reducing NAD. Acetate is then combined with coenzymeA to produce
The two carbon molecule bonds four carbon molecule called oxaloacete forming a carbon molecule knew as citrate. The second step reaction is classified as oxidation/reductions reactions. This process is formed by two molecule of CO2 and one molecule of ATP. The cycle electrons reduce NAD and FAD, which join the H+ ions to form NADH and FADH2, this result to an extra NADH being formed during the transition. In the mitochondrion, four molecules of NADH and one molecule of FADH2 are produced for each molecule of pyruvate, two molecules of pyruyate enter the matrix for each molecule of oxidized glucose, as a result of these eight molecules of NADH+ two molecules are produced. Six molecules of NADH+, molecules of FADH2 and two molecules of ATP synthesize itself in Krebs cycle. As a result, no oxygen is used in the described reactions. During chimiosmosis, oxygen only plays a role in oxidative phosphorylation. The next step is the electron transport; the electrons are stored on NADH and FADH2 and are used to produce ATP. Electron transport chain is essential to make most ATP produced in cellular respiration. The NADH and FAD2 from the Krebs cycle drop their electrons at the beginning of the transport chain. When the electrons move along the electron transport chain, it gives power to pump the hydrogen along the membrane from the matrix into the intermediate space. This process forms a gradient concentration forcing the hydrogen through ATP syntheses attaching
Every task performed by living organisms like humans and animals requires energy. Energy is needed to perform heavy working and exercise, in addition, human uses a great deal of energy while sleeping. For every action that requires energy, to provide energy to the systems of the body, such as muscles, nerves, heart, and brain needed many chemical reactions. Organisms use energy for things like growing, dividing, making proteins and metabolizing food at which all these processes require cells to make or break chemical bonds. In terms of the 'how', the Krebs cycle which involves the role of (ATP) in energy storage cells. Moreover, animals use sugars produced by plants and other organisms to produce the energy in the form of
ETC and OP take place on the inner mitochondrial membrane. Protein channels as complex I, complex III and complex IV connect the mitochondrial matrix with the intermembrane space (ISM).
Cellular respiration is a procedure that most living life forms experience to make and get chemical energy in the form of adenosine triphosphate (ATP). The energy is synthesized in three separate phases of cellular respiration: glycolysis, citrus extract cycle, and the electron transport chain. Glycolysis and the citric acid cycle are both anaerobic pathways because they do not bother with oxygen to form energy. The electron transport chain however, is aerobic due to its use of oxidative phosphorylation. Oxidative phosphorylation is the procedure in which ATP particles are created with the help of oxygen atoms (Campbell, 2009, p. 93). During which, organic food molecules are oxidized to synthesize ATP used to drive the metabolic reactions necessary to maintain the organism’s physical integrity and to support all its activities (Campbell, 2009, pp. 102-103).
while releasing energy from it's bonds. This is the energy used by the cell to produce
A cell splits glycogen into glucose, uses anaerobic metabolism to make ATP and a byproduct called lactic acid (Teachpe, 2016).