Autoimmune Iveitis Essay

In the eyelid the rash of shingles can cause an inflammation of the eyelids that comes to block the vision. Lashes may fall, and scarring may occur due to rupture of the blisters. In the cornea the virus invades, it can cause ulcers and inflammation that will lead to a permanent cicatrization. This can result in blurred vision and blindness. You may also suffer from a loss of sensation in the cornea; For example, you will not be able to tell if you have a flap or if you have grit in your eye. On the uvea, including the iris. Inflammation of the iris occurs frequently when you suffer from shingles in the eye and this can lead to permanent scarring. It can also cause fluid pressure inside the eye to increase, increasing the chances of developing glaucoma. In the case of retinal infection, the cells to begin dying, creating blurred vision and pain in the eye. If left untreated, infection can lead to permanent blindness. A retinal detachment may also occur. If shingles invades the optic nerve it will inflame it, which can cause nerve damage similar to those caused by glaucoma, resulting in loss of

Celiac disease is an autoimmune disease triggered by ingestion, of gluten-containing foods. The disease results from inappropriate T cells immune response against gliadin in genetically predisposed people. Individuals with this disorder have high levels of antibodies to a variety of antigens. The resulting immune response produces a strong inflammatory reaction that results in loss of absorptive villi from the small intestine. After the subsequent lesions are widespread, they may weaken absorption of macronutrients and micronutrients. Small bowel involvement

Have you, a friend or family member been diagnosed with an autoimmune disease? They include multiple sclerosis, type 1 diabetes, rheumatoid arthritis, lupus, Crohn’s disease, and more than 80 other chronic, lifelong diseases. Attend the Illuminations Luncheon on Oct. 28 and learn how Benaroya Research Institute at Virginia Mason (BRI) is “Turning the Tide Against Autoimmune Diseases.” Read More ...

The small intestine is lined with microvilli (sing. microvillus) and mucosa that entrap and absorb the vital nutrients the body needs to sustain healthy function. With celiac patients, consuming gluten-containing foods causes the breakdown of these microvilli and the mucosa, causing malnutrition through the inability to absorb the necessary vitamins and minerals. As celiac is an autoimmune disorder, it stands to reason that the antibodies are attacking the small intestine and are therefore able to be detected in the blood. This reasoning has been discovered to be true and has become “an

The Human Body is an oasis of life. Still, every waking moment of our lives, our bodies endure vicious attacks. Bacteria, viruses, fungi, microbes, toxins, and parasites - I like to think of them as invaders from the outside world. Each invader is equipped with its own specialized method of attack. On a microscopic level, our bodies fight a life-long war. As the battle rages, our immune system kicks in and protects us against the perils of illness. The immune system is not made up of one particular tissue or organ. Instead, an arsenal of defense cells; including lymphocytes, bone marrow, and leukocytes join forces to keep us healthy. Besides the occasional times we get caught in the crossfire with a common cold, a healthy immune system keeps

To understand autoimmune diseases, the general characteristic of autoimmunity must be addressed. Autoimmunity is defined, in short, as “ misdirected immune response”. A healthy person is equipped with the mechanisms necessary to defend the body from pathogens within the immune system. When autoimmunity is present in an individual, something within the immune system is

It is of great interest to see how far the scientific community has come across with identifying the genes and functions of each encoding protein. The science brought different interventions, as each gene has the possibility of interaction and the whole cellular environment has a type of role to engage in the complex day to day regulation of our eukaryotic cells.

Sjogren’s Syndrome is an auto-immune disorder that affects the entire body. The immune system protects our bodies from disease and infection, but with an autoimmune disease, the immune system attacks healthy cells in the body by mistake (Autoimmune Diseases, 2017). In Sjogren’s syndrome, the immune system attacks the glands that make tears and saliva. (Sjogren’s Syndrome, 2017). Pathogenic organisms and other foreign substances are detected by T-lymphocytes and B-lymphocytes because they contain antigens (McKinley, et al, p. 684). The immune system is generally very effective in distinguishing a self-antigen from foreign antigens; however, a malfunction involves the immune system reacting to self-antigens as if they

S. epidermidis account for anywhere from sixty to ninety percent of our microbiota; they exist in a commensal relationship, colonizing in the armpits, between the legs, in the nose, throat, and eyes where they are able survive by metabolizing secretions (John et al.; Namvar et al.; Otto; Tortora et al. 404 and 591). As part of our natural microflora S. epidermidis provide for competitive exclusion to potentially harmful bacteria, such as coagulase-positive staphylococci, Staph. aureus. Likewise, our body’s use nasal secretions, ciliary action, conjunctiva, and tears to limit S. epidermidis colonization. Typically S. epidermidis function as innocuous, friendly bacteria on the human skin, it is not until this barrier is broken that S. epidermidis may act as an enemy (Otto; Tortora et al. 592). Immunosuppressed people and very low birth weight newborns are at greater risk for S. epidermidis infection as well (Cheung and Otto; John et

The human gut microbiota has become the subject of researches in recent years and our knowledge of the resident species and their potential functional capacity is rapidly growing. Our gut harbors a complex community of over 100 trillion microbial cells. Therefore, our gut microbiota evolves with us and plays a pivotal role in human health and disease. This has clear effects on physiologic, immunologic, and metabolic processes in human health, aberrations in the gut microbiome and intestinal homeostasis have the capacity for multisystem effects. Changes in microbial composition are implicated in the increasing for a broad range of inflammatory diseases, such as allergic disease, asthma, inflammatory bowel disease (IBD), obesity, and associated

Lupus “is predominantly a disease of young women (most commonly affecting women between the ages of 15–45) but can affect men as well” (Hughes & Sangle 2012). “Women of color (Asian and African American) are two to three times more likely to develop Lupus than Northern European women” (Hughes & Sangle 2012). It is a chronic autoimmune disease that affects many parts of the human body including the immune system, joints, skin, and organs within the body. Normally, the human body would produce proteins (antibodies) that protect the body from invaders such as viruses, bacteria and germs. In the human body afflicted with Lupus, the body becomes “autoimmune” and the body is unable to tell the difference between foreign invaders such as those named

Pathogens can quickly change and adjust to escape detection and destruction by the immune system. Therefore, several defense mechanisms have too changed to identify and neutralize pathogens. Disorders of the immune system can cause autoimmune disease, inflammatory diseases, and cancer. Immunodeficiency appears when the immune system is less functioning than normal, causing in recurrent and life threatening infections. Immunodeficiency may be an effect of inherited disease passed down. Autoimmunity happens from a hyperactive immune system attacking normal tissue believing they are foreign organisms. Some familiar autoimmune diseases are hashimoto’s thyroiditis, diabetes mellitus type 1, systemic lupus erythematosus, and rheumatoid arthritis.

The DCs can sample antigens in the intestines and transfer them to T cells, which then differentiate into various effector T cells, also known as Treg cells. The type of Treg cells created depends on the cytokine signals that are produced by microbial cells. Without specific Treg cells, the body cannot create important anti-inflammatory immune cells such as IL-10 and IL-22. Bacteroides and Lactobacillus species are documented to influence the production of IL-10.[6] Therefore, the presence and composition of gut microflora is important in reducing inflammatory responses to

With autoimmune diseases, the underlying issue is similar. The body's immune system becomes unable to recognize healthy cells from diseased cells. Consequently, the immune’s own defense mechanism produces antibodies that attack the normal tissues and cells. Autoimmune diseases

Autoimmune Deficiencies are very complex and misunderstood diseases in the world today. Most people are uneducated and unaware of what these diseases actually are and the trials people diagnosed with these illnesses face. Due to their lack of education there is also a lack of compassion shown; causing an awkward, silent tension between people. Lupus is a subcategory of the Autoimmune Deficiencies. Those with this tend to be silent about their struggle, causing it to be unnoticed in the world. However, there have been efforts made medically to give these people a true voice. In order to give them a voice people must know what Lupus actually is, the causes and symptoms of it, and new research that can help improve the quality of life for those who have the disease.