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Ayahuasca Substance Abuse

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Summary
In 2011, a preliminary—though not well-conducted—study of ayahuasca-assisted treatment for drug abuse was conducted in Canada. As part of the study, twelve subjects with addictions to alcohol, cocaine, tobacco, cannabis, opiates, and other drugs participated in several days of group therapy and two ayahuasca treatments. Data concerning psychological and behavioral conditions were collected through a series of surveys both before and after the completion of the study. The categories being assessed were comprised of mindfulness, empowerment, emotional regulation, hopefulness, and quality of life. The measures were then calculated by using ANOVA, or analysis of variance, which is a statistical model used in order to analyze the differences …show more content…

government over 700 billion dollars annually. A survey conducted by the Substance abuse and Mental Health Services Administration regarding drug use and health reported “23.5 million persons aged 12 or older needed treatment for an illicit drug or alcohol abuse problem in 2009 (9.3 percent of persons aged 12 or older). Of these, only 2.6 million—11.2 percent of those who needed treatment—received it at a specialty facility” (1). Desperate to find solutions to treat substance abuse problems other than the often unsuccessful rehabilitation programs, researchers are now considering the use of psychedelic substances to treat these issues. This idea is not the first of its kind. During the late 1960s and early 1970s, American scientists studied the effects of LSD on over 40,000 people including its effects on alcohol use. However, because many of these hallucinogens are classified as Schedule I substances and other restrictions imposed by the United States Drug Enforcement Administration (DEA), studies involving these drugs cannot be conducted easily within the United States (2). Fortunately, countries with more lax drug policies, such as Canada, allow for these substances to be studied. One such substance is …show more content…

First described academically during the 1950s by Harvard ethnobotanist Richard Schultes, ayahuasca is derived from the Brazilian Banisteriopsis caapi and Psychotria viridis. The resulting brew is highly concentrated with a compound known as dimethyltryptamine (DMT) which causes vivid, dream-like hallucinations (3). DMT is found endogenously in many organisms, with small amounts present in the pineal gland of mice and perhaps that of humans. However, because of a family of enzymes in the liver known as monoamine oxidases, ingestion of DMT-containing substances has no effect on humans as the compound is quickly broken down. It is for this reason that the ayahuasca brew must be made with the specific species of plants. By boiling the plants for several hours, alkaloids which act as monoamine oxidase inhibitors (MAOIs) are released. This inhibits the enzymes from breaking down the DMT and allows the substance to cross the blood brain barrier

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