Benadryl Research Paper

4. What type of drug is chlorpromazine, and where was it first tested on patients? Antipsychotic, A new phenothiazine drug, chlorpromazine, was synthesized in France in 1950 and was tested on such patients. In 1952, two French psychiatrists, Delay and Deniker, announced that the drug exerted a specific effect in diminishing the symptoms and signs of psychosis in patients with severe mental illnesses. (Hart & Ksir, p. 171)

In 2007, the Mylan pharmaceutical company purchased the rights to the EpiPen. The drug inside the EpiPen is Epinephrine, which is a synthetic adrenaline that is used to treat possible anaphylaxis shock caused by allergies. “Evidence-based guidelines recommend the prompt administration of epinephrine as first-line treatment for an anaphylactic episode” (Dinakar, 2012). Millions depend on carrying the drug to live a normal life. Currently the EpiPen has no

Acetaminophen has been used for decades. In 1947 it was able to be bought by prescription only. Then in the 1960s it was then changed to be bought over the counter. It is one of the most commonly used analgesic-antipyretic medication for pediatrics and adults. The chemical name is N-acetyl-p-aminophenol (APAP). There is more than 200 over the counter medications, prescriptions that has acetaminophen listed as the primary drug. According to the American Association of Poison Control Center, acetaminophen is the most common pharmaceutical that has intentional and unintentional poisoning and toxicity. The most common of NSAIDs is aspirin (acetylsalicylic acid), it was put into modern medicine in 1899. Ibuprofen also known as Advil or Motrin, a

There is no doubt that the study of chemistry has changed the world dramatically. Under the right circumstances, many advances in the realm of chemistry can save lives. The EpiPen® has been a wonderful chemical developed tool, aiding in potentially lethal allergic reactions such as anaphylaxis. It is important to understand what an EpiPen® is, and how it works to one day save a life if necessary. What will further be discussed is what an EpiPen® is, how it is made, used, and how it works chemically in the human body.

One subclass of amphetamines is called methamphetamine. This subclass (at one time called "speed") has been around for a long time and gave rise to the phrase "speed kills" in the1960s. First synthesized by the German chemist L Edeleano in 1887, it was originally used as a relief for respiratory complications such as asthma and nasal congestion. The discovery of highly reactive properties of the drug led to discoveries of more dangerous versions of the drug. In 1919, The Japanese Chemist Ogata created the first methamphetamine, and in 1929 the company Smith, Kline & French took over the drug. By 1932 Smith, Kline & French owned “Benzedrine” and made it available through prescription. In 1937 it was approved by the American Medical Society, and renamed it “Adderall.” (Arbor)

At the start of the war, soldiers used sulphonamide drugs which was nicknamed sulfa. Gerhard Domagk discovered sulphanilamide in 1935. Domagk found that by changing the chemical compound of the drug prontosil, the product could kill and reduce the growth of bacteria. Each soldier was issued with a sulfa powdered dressing, some sulfa powder and 8 sulfa tablets. They were also given training on how to

The benefits is that rapid onset of action, lower cost, rapid onset of action, and effectiveness for intermittent symptoms and over-the-counter availability.. The risk of oral antihistamine is systemic side effects such as sedation, dry eyes, and urinary retention (Seidman et al., 2014).

Propofol is a hypnosis which is used to keep the patient sedated during the surgery this also used to keep patients sedated (Stonebridge, 2012). The most common physiological effects of Propofol are the local pain during the injection, eyes rolling back; coughing after anaesthesia, arching body spasms, muscle jerks, muscle twitching, slow heartbeat, hot flushes, increased breathing, hiccups, and periods of not breathing this is when the anaesthetist oxygenates the patient since the patient is sedated. Low blood pressure is also a side effect which shows on the monitor that the blood pressure levels have dropped once the Propofol has been injected (Stonebridge, 2012). Another common side effect is increased levels of fat in the blood, which

The first time I read the above passage, I was fourteen and in a rush to finish the book as fast as I could. I learned only a week prior the film Jurassic Park had been based off a book, and, desperate for reading material, I checked it out of the library and flitted through it in a single day. It was filled with action I could barely stay in my seat through and theories I could barely understand. I loved it. Not until my third read-through did this sentence catch my eye, but when it did it shifted the way I thought about dinosaurs from that point on. It is so easy to think of dinosaurs as positioned bones and still murals rather than dynamic creatures that evolved over an enormous period of time, adapting

Salbutamol is a generally utilized asthma solution sold under various exchange names, including Ventolin and Proventil. It is a bronchodilator, implying that it follows up on particular cells in the airway route to augment the air entries. Its instrument of activity, which is through association with a particular cell receptor, the beta-2-adrenergic receptor (b-2AR), has been seriously considered. The coupling of salbutamol to b-2AR "actuates" the receptor, invigorating it to deliver chemicals that in the end lead to unwinding of the airway passage muscles. Salbutamol is composed of an aromatic ring, hydroxyls and an amine and t-Butyl group.

Alexander Fleming discovered the penicillin in 1928. He was a Professor of Bacteriology at St. Mary’s Hospitals in London. The penicillin was called a miracle pill because it was the first antibiotic that saved people lives from infection. People that was infected by a wound, had gonorrhea, or rheumatic fever, the penicillin cured those symptoms. This penicillin was produce by bacteria and fungi. Before Alexander Fleming discovery, the ancient Egyptian practice the same method by curing infected wounds with molded bread. (Endocrine, 2008)

The work that led to the discovery of Prozac started at Eli Lilly and Company in 1970 and two discovers which where Bryan Molloy and Robert Rathbun. At that time the antihistamine diphenhydramine showed some antidepressant-like properties. 3-Phenoxy-3-phenylpropylamine, a compound structurally similar to diphenhydramine, it was taken as a starting point, and Molloy synthesized dozens of its derivatives. Wishing to find a derivative inhibiting only serotonin reuptake, an Eli Lilly scientist, David T. Wong, wanted to retest the series for the in vitro reuptake of serotonin, norepinephrine and dopamine. This test, that was tried out by Jong-Sir Horng in May 1972, Wong published the first article about Prozac in 1974.

Jae Y. Choe, PhD., Drug action and interactions: antihistaminic drugs. Unites States: McGriw Hill Medical; 1937, p. 93-94.

Before David Jack invent ventolin, there were about thousands of people died by asthma attack without corresponding medication. But now when people have asthma attack, they can use ventolin to stop the asthma attack, it is really quick and effective.

Throazine, other major tranquilizers developed 1952 - The French psychiatrists Jean Delay and Pierre Deniker report that Thorazine ® calms hospitalized chronic schizophrenic patients without causing clinically significant depression. The drug is called 'hibernotherapie' because patients became quiet, like