Bexsero Case Study

These vaccinations will be given to babies at the ages of two, four and 12 months as a routine. The reason for the vaccination is so that there would be less risk of infants under the age of one getting the meningitis B infection. Campaigners have stated the vaccination could potentially prevent up to 4,000 cases by

The father decided to do the biopsy and they took her back. Studdert removed an inch long ellipse of skin and tissue stretching from the top of the foot to the tendon. Then, he removed some of the muscles at the center of the redness. Both samples were sent to the pathology department where a dermatopathologist had later confirmed their suspicions. When she was taken into surgery, the destruction was obvious and they had questioned the need for an AKA or BKA. However, they decided to trust their guts again and did a debridement and flushed out the muscles. Two hours later, she was transported to another hospital and put in a hyperbaric oxygen chamber for two hours to boost muscle repair. The following day, she was taken back into surgery to remove more of the infected muscle and they decided to increase the oxygen treatment to twice a day for two hours. Twelve days later, she was released from the hospital bacteria free. A patch of skin, about sixty-four-square-inches, had been removed from her thigh and used as a skin

Ten to fifteen percent of cases are fatal. Ten to fifteen percent of patients who recover have permanent hearing loss, mental retardation, loss of limbs, brain damage, or learning disability in ten to twenty percent of survivors. (WHO, 2004) The groups at risk for this disease include the general population, infants and young children, refugees, household contacts of case patients, military recruits, college freshmen who live in dormitories, people exposed to firsthand and secondhand smoke, and microbiologists who work with isolates of Neisseria Meningitidis. (CDC, 2004)

This baby’s mother had genital herpes and he soon died a few hours later with organ failure.

This dermal infection can occur at any age but particularly affects young children from the ages two to five years old. Globally, it affects more than 162 million children, predominantly those that attend school or daycares are more likely to contract

“This is a very rare condition, but it still is an important condition for the scientific community to learn more about, particularly because of the potential for long-term and disabling consequences,” said Dr. Kevin Messacar, a pediatric infectious disease physician and researcher at Children’s Hospital Colorado. “Even though there are very few cases in the country, as researchers and scientists, we need to move the field forward in order to better prevent and treat the condition” he added.

The Food and Drug Administration (FDA) audits clinical-trial information for new medications and figures out if the advantages of these medications exceed the risks.1 This necessity, enacted in 1962,2raised the bar to regard and diminished the probability that new medications would be inadequate or reason significant wellbeing issues. Growing such information about investigational medications requires some serious energy for the evaluation of items that at last end up being sheltered and compelling. Such a period slack can be an issue if elective medications for the condition are not accessible. The FDA hence added to an arrangement of extended access to allow patients with genuine conditions to get investigational medications before formal

In the 2015 study conducted by Popov, a 61 year old male was diagnosed after arterial surgery. The patient came in complaining of pain. This is common along with inflammation and a red, hot feeling in the area. The person may also experience a fever. In other cases, some people have been infected after surgery. It is more likely to occur in an individual that has a compromised immune system. In one instance of the infection, the person contracted on the forearm around the area of what was constant drug use. The source would have been a dirty needle. Another individual contracted the bacterium on the upper leg. This was suspected to be the site of an insulin injection for a woman with diabetes.

• Meningococcal vaccine. One dose is recommended if you are age 19–21 years and a first-year college student living in a residence hall, or have one of several medical conditions. You may also need additional booster doses.

In a world of vaccinations and public healthcare, it is easy to forget that we are constantly surrounded by disease causing microbes. Throughout this unit we have studied the human bodies constant fight with microbes and what happens once they accumulate. In this paper I will discuss meningococcal meningitis, its disease causing microbe, how the bacterium enters and exits the body and, the symptoms caused by the bacterium. I will also discuss the impact this microbe has on human health and any treatments available.

Likewise, for many years, vaccinations have continued to keep the spread of diseases low. By doing this, they have lowered the amount of deaths and saved lives since their beginning. In fact,“It is estimated that just 9 of the routinely recommended vaccines prevent 42,000 deaths and 20 million cases of disease in every birth cohort” (Epling E1). Bacteria and viruses can take hold of their victims in a few different ways. For example, they can infect through the respiratory system, causing chest pain and coughing. One of the most fatal ways for children to be infected is through Meningitis. Meningitis is an infection, in the cerebrospinal fluid that surrounds the brain and spinal cord. During the infection, people can develop headaches,

It is caused by mycobacterium leprae and there are two major strains, tuberculoid and lepromatous. red lesions and loss of feeling around and inside the lesions are the first signs of the nerve damage as a result of the bacterial infection. This disease affects the central nervous system and the peripheral nerves. If left untreated, it can lead to further nerve damage and development of ulcers. Thankfully, we have treatments available to cure the bacterial infection. Unfortunately, we do not have a way to reverse the damage caused by the infection, nor do we have anything besides a vaccine that only works for half of the cases seen. In other words, no way to stop the spread besides isolating the contagious victims from close continued contact with other people which can cause severe emotional and psychological damage to the victim, even after the infection is no longer

After attention was paid to the prescription NSAIDs, such as Merck's Vioxx, and on a recommendation by the FDA, Pfizer withdrew Bextra from the U.S. market, refer to an increased risk of heart attack and stroke and also the risk of a serious, sometimes critical, skin reaction, in 2005.Other reported side-effects were angina and Stevens–Johnson syndrome.

The bacteria Neisseria meningitides, commonly known as meningococcus, is an important cause of bacterial meningitis worldwide. There are 13 serotypes, however globally, most meningococcal disease is caused by serogroups A, B, C, W135 and Y. (NCIRS:2014) Serotypes have varied geographical distribution, with serotypes B and C predominant in Europe, North America and Australia. The disease is serious and in some cases can be life threatening. The disease can cause meningitis (inflammation of membranes surrounding the brain and spinal cord, septicaemia, pneumonia, conjunctivitis and arthritis. (Australian Department of Health (ADOH:2014) This report is collated by the US Department of Health with the aim of identifying the categories of informational required to assess whether a meningoccaccal B vaccine should be included in the government funded National Immunization Program (Part 1). Part 2 will introduce the program evaluation of a case study of the MenB vaccine introduced in the US in a specific age group. Finally, this report will be submitted to the National Immunization Technical Advisory Group to make the final decision on whether the MenB vaccine will be included in the National Immunization Program. This decision will be included in the final section of the document.

Meningococcal disease is a large concern in the medical field because it is unbiased towards the patients it infects. There has been limited success in trying to eliminate this disease. Antibiotics play a role in helping to treat patients with bacterial meningitis, and steroids have been tested to help reduce risk factors. Prevention has also become a key issue because meningitis can only be spread through direct contact with infected body fluid. The best prevention is to maintain clean hygiene. Vaccines are another way of preventing disease. However, there are multiple serogroups of meningitis that makes creating a universal vaccine extremely difficult. So far, there have only been two