Binding Sites Of Drosophila And Humans

The observed results from the ¬F1 generation were that the phenotypes had to be EeNn x EeNn. The expected results for the F1 generation were also EeNn x EeNn because the P generation phenotypes for the male fruit fly were Ee and were Nn for the female P generation flies. The expected results for the F2 generation were a 9:3:3:1 ratio from the phenotypes NENenEne x NENenEne. The Chi squared value turned out to be 4.14 when the differences between observed and expected results were

In this experiment we tested to see what the offspring of an unknown cross of an F1 generation would produce. After observing the F2 generation and recording the data we found some of the Drosophila showed mutations, two in particular. The mutations were the apterus wings, and sepia eyes. After collecting our data through observation, a Chi-test was conducted resulting in a Chi-value of 5.1 and a p-value of .2. Since the p-value was greater than 0.05, there was no significant change in the data. This proved that the Drosophila flies still followed the Mendelian genetics of a 9:3:3:1 ratio.

The Human Genome Project is a worldwide research effort with the goal of analyzing the structure of human DNA and determining the location of the estimated 100,000 human genes. In parallel with this effort, the DNA of a set of model organisms will be studied to provide the comparative information necessary for understanding the

The goal of this study was to induce a deletion in the DMAP1 gene on chromosome two in Drosophila melanogaster through P-element mobilization. The DMAP1 gene may be an essential gene, however not much is known about it. We attempted to uncover the function of DMAP1 by creating a series of genetic crosses and selecting for brown-eyed non-stubble male flies that may have the deletion. To test whether these flies had the deletion, we produced PCR products and ran them on an agarose gel, which resulted as inconclusive. We created a balanced stock of flies homozygous for the deletion to see if the

The mapping of human genes has allowed for certain genetic disorders to be identified according to the genes that it is affecting. This has created a map that other individuals' genes can be compared to in order to determine any mistakes or any alterations that may lead to the development of a disease. Any changes in epigenetic

Drosophila Melanogaster, commonly known as fruit flies, are highly important model organisms in pertaining to biological research. The logic behind their recurrent use is due to their: easy culture in the laboratory, brief generation time, and ability to produce large numbers of offspring. In this report, we created isolated virgin D. Melanogaster from the original three populations we were given and then created crosses between them. Upon observation, we noticed an unusual mutant that arose from two of the three created crosses. We suspected that this genetic mutation had previously been discovered and named.

Jack J, DeLotto Y. Effect of Wing Scalloping Mutations on Cut Expression and Sense Organ Differentiation in the Drosophila Wing Margin. Genetics. 1992;131(2):353-363.

Genes can either be sex-linked or autosomal. If a gene appears mostly in one sex chances are the gene is sex-linked and if it appears frequently in both sexes it is most likely autosomal. Using Drosophila melanogaster, also known as the fruit fly, we will determine whether the gene is sex-linked or autosomal. Drosophila melanogasters have a relatively short life span and are an excellent organism for genetic studies because it has simple food requirements, occupies little space, is hardy, completes its life cycle in about 12 days at room temperature, produces large numbers of offspring, can be immobilized readily for examination and

The book begins by exploring gene variations in the human genome, and finding genes that show “strong signs of selection” over the last 10,000 years or so. This is possible due to relatively recent

Introduction For centuries, researchers have used Drosophila melanogaster, the common fruit fly, to study genetics. The benefits of using the fruit fly includes: its relatively short generation time, its large amount of available offspring for data, it is easy to store and handle in the laboratory and it is easily and cheaply obtained. Cross-breeding of four types of fruit flies were used in this experiment including: wild type males with normal wings vs. vestigial wing females, wild type males with red eyes vs. white eyed females, wild type male with red eyes vs. sepia eyed females, and wild type males vs. wild type females. In basic mendelian genetics, the terms dominant, recessive and sex-linked are used to describe the different types

Dobzhansky, T. (1930). The manifold effects of the genes stubble and stubbloid in Drosophila melanogaster. Z. indukt. Abstamm.- u. VererbLehre 54: 427-457.

Genetics is the study of genes, heredity and variation in living organism. It is important in understanding how heritable traits are passed down from one generation to another. Here in this study, the identification of a particular mutation was explored by discovering how it is transmitted and where it is located. Drosophila melanogaster, a species of fruit flies, was the model used to illustrate the process of gene inheritance. Virgin female fruit flies were collected over a span of two- three weeks and crossed with balancer chromosome male fruit flies. The progeny, also known as the F1 generation, was then used to perform a test cross. The test cross was done between an F1 male and a virgin female from the parental generation. The results of the test cross, determined the mutation as well as which chromosome it was located on.

In this experiment, two types of Drosophila melanogaster (fruit flies) were used: mutant and wild type. The wild-type flies had normal shaped wings and red eyes, while the mutant had either vestigial (short) wings or white (blind) eyes. The strains used for each mutation were W118 (white eyes) and strain 432 (vestigial wings). The flies with the vestigial mutation had the allele genotype of Vg-Vg- for female and the males had the allele genotype of Vg-Y. The flies with the white-eyed mutation had the female genotype of XwXw and the males had the genotype XwY. The population was created by crossing equal numbers of WT and Mutant flies. The populations were allowed to randomly mate for 10 generations in order to reach Hardy-Weinberg Equilibrium. We used half of the original population for the experiment and the other

This experiment looks at the relationship between genes, generations of a population and if genes are carried from one generation to another. By studying Drosophila melanogaster, starting with a parent group we crossed a variety of flies and observe the characteristics of the F1 generation. We then concluded that sex-linked genes and autosomal genes could indeed be traced through from the parent generation to the F1 generation.

It’s the model organism which founded and still helps aid in these genetic discoveries. Our results showed how to map three genes on one chromosome, understand the mapping distance between genes, their linkage and how they interact with each other to show a specific phenotype, using a simple analysis program. This has been made available through the mapping of the entire Drosophila m. chromosome sequence. It is one of the most intensely studied organisms in biology (4) as it is an effective model organism. The completion of the Drosophila melanogaster genome was 3 years before that of the HGP and discoveries throughout the mapping process of drosophila m. aided in how to map the human genome. It was used as a test system to explore the likelihood of being able to sequence a whole genome for a large complex eukaryote. It was found that Drosophila m. provided a complete, high quality genomic sequence which has been used by the research community as a model organisms (4) when researching molecular mechanisms underlying development, behaviour, aging, genetic inheritance and other metazoan processes