Bioethics And Epigenetic Research

   The Human Genome Project is the largest scientific endeavor undertaken since the Manhattan Project, and, as with the Manhattan Project, the completion of the Human Genome Project has brought to surface many moral and ethical issues concerning the use of the knowledge gained from the project. Although genetic tests for certain diseases have been available for 15 years (Ridley, 1999), the completion of the Human Genome Project will certainly lead to an exponential increase in the number of genetic tests available. Therefore, before genetic testing becomes a routine part of a visit to a doctor's office, the two main questions at the heart of the controversy surrounding genetic testing must be

In an ever evolving society, the increased use of technology has become a staple in our day to day lives. With the constant advancements of technology the ideology of cloning has now become a reality. The increasing use of science today is slowly leading to the development of cloning and genetic selection. By altering the genetic make-up of a being, scientists have brought about several questions on how the population would adjust to the “super-beings,” and what benefits and consequences both human and non-humans would gain with their creations? Authors Francis Fukuyama, who wrote “Human Dignity,” and The Dalai Lama, writer of “Ethics and the New Genetics,” has called into question the use of cloning and how it could possibly affect others. With the creation of “super-beings,” humans would ultimately suffer a bigger separation from each other and create unfairness among the human species such as a stronger and more intelligent being.

I agree with your opinion in how genetic technology could leave a negative impact to our society. I believe the idea of genetic engineering is not natural. We have no idea of the harm that could result from this technology. Genetic engineering is another step in giving humans their desires. I believe that altering the DNA of any life form is not just. Genetically manipulating a life form could put an imbalance in nature and society. No one should have the right to manipulate the genetics of other life forms. The idea of genetic engineering is be consider unethical because it is enforcing animal cruelty. Furthermore, I am appalled that some parent choose their child’s appearance, rather than go through the ‘natural’ process, to prevent bullying and discrimination.

Online technologies are beneficial to the modern world. It can improve a person’s education, business, and helps in everyday life hassles. It has become an essential part of the way that people live and it is very likely that people would be a loss without it. In “Ethics and the New Genetics,” the Dalai Lama claims that to ethically use new technological advancements we need to develop a “moral compass”. Peter Singer, in “Visible Man: Ethics in a World without Secrets,” discusses whether new technology and “openness” makes our lives better, or if the lack of privacy takes away the rights of individuals. Both authors discuss how technology is advancing very rapidly and can significantly have major pros and cons to society. The two authors, however, have different viewpoints in which how the society can determine when technology has become ethical. Dalai Lama is firm believer that technology is evolving so fast that ethics could hardly keep up with it. He addresses how people should have ethical standards when dealing with the internet. Thus, he is directly proving to us how he would want society to ethically determine when and how technology should be used. Yet, on another spectrum, Peter Singer argues that although ethically, internet is invading our privacy, this invasion of privacy is the only way that the public is safe and people should brutally discover the truth about everything but somehow it can cause harm. Peter Singer and Dalai Lama both agree how the new online

I support the guidelines outlined by Kitcher for the use of genetic information because of their responsible and ethical nature. I believe that future generations will benefit as a direct consequence of these guidelines. I shall begin by defining eugenics as the study of human genetics to improve inherited characteristics of the human race by the means of controlled selective breeding.

The benefit of genetic science for individuals is that it can determine if the person has a possible genetic disorder and give them

Epigenetics is the future of science. It has evolved from being a science that very few believed in, to one that will shape medicine as it is known. As the Human Genome Project began, the goal was to determine which genes controlled what phenotypes in a human. After all the genes were identified and mapped, the expression of the genes that the scientists had just discovered was also beginning to be analyzed (EPIGENETICS). Although every gene had been identified and associated with a function, there were genes that if not expressed or not turned on, would create a different scenario. That is, the idea that the genotype of an individual would determine their phenotype was reinforced. Epigenetics however is the study of the switching on or off of the genes responsible for a particular action (Feinberg). For example, all of the organs of a single person have the exact same DNA as the others, yet a lung looks drastically different from a kidney. This is due to the expression of the genes responsible for creating a specific organ. If scientists are able to control the switching on and off of these genes, then many extraordinary possibilities exist.

Genetic testing has brought about many changes in the way many couples look at conceiving and raising families. Through genetic testing you are able to screen for the increased chance that a fetus may have one of many congenital disorders, or even identify gene changes that are responsible for a disease that has already been diagnosed (Genetic Testing, March 2015). Unfortunately genetic testing is not always exact, in some cases giving parents false negatives or false positive results. Even if the results are accurate, there is the burden of knowledge once you know the results indicate a genetic abnormality such as Down’s syndrome. While caring for a 2 year old male patient with developmental delays and anotia, I learned that genetic testing had been started but never completed on the child. Genetic testing could help to identify genetic disorders that led to the child’s developmental delays and possible future disorders that may develop. The ethical dilemma I will be discussing to the ANA Ethical dilemma of the impact of informed consent of genetic testing on children for adult onset diseases and disorders.

Through studies such as the Human Genome Project, researchers have discovered more information than ever about genes, chromosomes, DNA, and specific medical conditions and diseases. Although, we cannot hold modern medicine responsible for discovering biological markers and treatments for certain medical conditions, historical events such as Buck v. Bell need to be brought into the classroom for students to understand how linking complex human traits and behaviors to heredity is erroneous and may lead to unjustifiable social policies. Human traits and behaviors are more so based upon an individual’s environment rather than the genes an individual inherits. Many historians worry that contemporary economic and social problems can give rise to a new eugenics movement. Given the constant struggle over limited resources, we can expect eugenic proposals to resurface overtime. The story of Carrie Buck provides a point of departure for discussing and understanding multifaceted issues including the understanding of linking traits to certain behavioral aspects, the understanding of the legislative system and court rulings and understanding what decisions and when these decisions should be justifiable to people within society. Providing education on such controversial and political issues to future generations could

An Enhanced Genotype: Ethical Issues Involved with Genetic Engineering and their Impact as Revealed by Brave New World

The Goal of the Human Genome Project is to obtain genetic mapping information and to determine the complete sequence of all human DNA by the year of 2005. The project started in 1990 and 180 million dollars are being spent on it annually. This adds up to a total of over 2 billion dollars for the 15 year budget. Of this 2 billion dollars budgeted, 5% is spent annually on the ethical, legal and social issues. This report focused on some of these issues.

I also learned that these epigenomes change because of environmental factors which include what we do, what we eat, what we drink, or what we smoke. This has been said to be one of the pivotal contraries amongst epigenetics and genetics. I found the groundbreaking study identical twins very interesting. The point of this experiment was to discover if twins were epigenetically identical or not. After obtaining DNA from 40 sets of twins, researchers were able to conclude that as twins age, the chance of epigenetic differences increases.

The fear of genetic discrimination is a phobia gripping many people around the world. People find themselves asking, could my genetic information raise my health bills? Could this cause me to be rejected from a job opportunity? These anxieties are causing people to lash out at genetic research, and ultimately the human genome project. People do not want our understanding of human genomics to advance. This is because the risks of the development of the technology could inflict on them. A major risk is genetic discrimination. I believe that genetic discrimination is wrong and governments should continue to prevent it because it is an invasion of privacy, it violates equity, and it could really hurt people with genetic

On the other hand, it is important to evaluate the potential of epigenetics as much as necessary. For example, in the case of the treatment of cancer, the impact of epigenetics is currently overestimated. Even though epigenetics can open new opportunities for the better understanding of the causes of cancer and the factors that are likely to contribute to abnormal changes in our cells, it can not and does not offer the cure for the treatment of cancer. Instead, epigenetics just gives insights into better understanding the causes.

The human genome project is something that I have been very interested with ever since first learning of it. I had heard bits and pieces of what it is about, but my interest was greatly stimulated by Dr. Whited in basic genetics 311 last spring. The discussion that we had regarding the project left me with several ideas and questions about not only the process and ethics involved, but the future of the study of genetics as a whole.