Biological Process Of Schizophrenia Research Paper

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- This paper asked what is the biological process that underlie a disorder like schizophrenia?
- It was known that schizophrenia is a heritable brain illness with unknown pathogenic mechanisms. Schizophrenia’s strongest genetic association includes variation in the major histocompatibility complex (MHC) locus. The genes and molecular mechanisms accounting for this, however, have been challenging to identify. The pathogenic mechanisms underlying schizophrenia are unknown, but observers have repeatedly noted pathological features including excessive loss of grey matter and reduced numbers of synaptic structures on neurons.
- This paper concluded that the association in part from many structurally diverse alleles of the complement component 4
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