Bioprinting Human Organs: The Past, Present, And Future.

The medical practice of organ transplantation has grown by leaps and bounds over the last 50 years. Each year the medical profession takes more risk with decisions regarding transplants, how to allocate for organs, and most recently conducting transplants on children with adult organs. “An organ transplantation is a surgical operation where a failing or damaged organ in the human body is removed and replaced with a new one” (Caplan, 2009). Not all organs can be transplanted. The term “organ transplant” typically refers to transplants of solid organs: heart, kidneys, liver, pancreas, and intestines. There are two ways of receiving an organ transplant: from a living human or an organ from a

A continuing problem exists in trying to close the gap between the supply and demand of procured organs in the United States. An increase in the amount of transplant operations performed has risen significantly over time. As a result, a new name is added to the national waiting list every 16 minutes (Duan, Gibbons, & Meltzer, 2000). It is estimated that about 100,000 individuals are on the national transplant waiting list at all times (Munson, 2012). Something needs to be done before these numbers get completely out of control. Despite the introduction of Gift of Life and many other educational efforts, the United

Today we are in great need of a solution to solve the problem of the shortage of human organs available for transplant. The website for Donate Life America estimates that in the United States over 100 people per day are added to the current list of over 100,000 men, women, and children that are waiting for life-saving transplants. Sadly enough, approximately 18 people a day on that list die just because they cannot outlive the wait for the organ that they so desperately need to survive. James Burdick, director of the Division of Transplantation for the U.S. Department of Health & Human Services confirms, “The need for organ transplants continues to grow and this demand continues to outpace the supply of transplantable organs”. The

The field of bioprinting, using 3D printing technology for producing live cells with extreme accuracy, could be the answer to many of the problems we as humans face in the medical field. It could be the end to organ waiting lists and an alternative for organ transplants. In 3D printing technology lies the potential to replace the testing of new drugs on animals. However, the idea of applying 3 dimensional printing to the health industry is still quite new and yet to have a major impact. Manufacturing working 3D organs remains an enormous challenge, but in theory could solve major issues present today.

In December of 1954, the first human organ transplant was performed in the United States between identical twin brothers. In the past sixty years, organ transplantation has become the gold standard in the treatment of organ failure from a number of underlying causes with dramatic improvements to recipients’ health and quality of life (Kaserman, 2007). From the first kidney transplant in 1954 to the late 1980’s, one of the biggest advancements was the use of cadaver organs. Organ rejection was the primary concern from the transplant team who knew that the use of cadaver organs posed higher risks of failure.

The American Medical Association’s Code of Ethics mandates that doctors tell their patients if their tissue samples are going to be used in research or will possibly lead to profits. Some post Nuremberg codes, such as the Declaration of Helsinki and the Belmont Report, say consent is required. These are not laws but ethical codes, but many institutions choose to get consent regardless. Issues on privacy are also resolved; the Health Insurance Portability and Accountability Act of 1996 prevents a privacy violation like the one that happened to the Lacks’ from occurring. Under the Common Rule, samples cannot be named using the donor’s initials, but instead by code numbers. The NIH has strict guidelines on tissue research, and it is illegal to sell tissues for medical treatments or transplants. In fact, under the Common Rule, people can even take their tissues out of research anytime they want to. There are many laws that protect patients and their rights, therefore new laws on tissue rights are unnecessary because there are already many proficient laws in

The shortage of organ transplants has been an ongoing crisis for years; the growing list of patients awaiting transplants has no end in sight, and the number of people dying while they waste away on the waiting list is not going to go down unless something changes.Society has turned away from alternatives to our archaic organ donation program, but there are other options available.The transplant community and society as a whole need to step back and rethink--to adopt a more open-minded views on organs as a resource in order to save lives and make meaningful changes to the national transplant program.

As such, with more government funding into the medical field, technology like the 3-D printer could one day develop into the future of all organ transplants. This process may happen sooner

Throughout time Organ transplanting has been an important medical procedure that has been present, not only in the United States, but around the globe. It is the process of surgically removing an organ from on patient and then transplanting it into the other. This practice is usually used when a recipient’s own organ fails to function properly or has

Available became controversial. While the question of the dialysis machine is still controversial, the health system was caught in another ethical dilemma regarding organ transplantation. Organ transplantation is closely linked to the issue of cleanliness because patients with kidney failure can get an organ transplant as an alternative to hemodialysis. The issue is complicated by the fact Medicare is financed by organ transplant, and there are those who believe that the distribution of rare transplant is not right. There are thousands of terminal patients whose lives can be saved by organ transplantation, but there are no formulas of work that can be used to determine which of the thousands of patients will be given priority. It is left to the discretion of medical officers to decide who is worth saving. The ability to keep someone alive by replacing one or more of their major organs is a splendid achievement of medicine of the 20th century.

Organ transplantation is a term that most people are familiar with. When a person develops the need for a new organ either due to an accident or disease, they receive a transplant, right? No, that 's not always right. When a person needs a new organ, they usually face a long term struggle that they may never see the end of, at least while they are alive. The demand for transplant organs is a challenging problem that many people are working to solve. Countries all over the world face the organ shortage epidemic, and they all have different laws regarding what can be done to solve it. However, no country has been able to create a successful plan without causing moral and ethical dilemmas.

As of 2016, 81.8% of the organs people are waiting for are kidneys (Organ Donation Statistics). Morally, the stem cells that would be taken for printing or replication should be used with consent, meaning they are not taken from a baby, alive or deceased. Of course, extensive research would have to be done before using 3-D printed organs for transplants and be FDA approved, but if people are desperate enough to turn to the black-market, using those people for clinical trials would be more productive and actually

DNA Fingerprinting, also known as DNA Profiling, is a method used to identify a person using DNA patterns that are specific to him/her. 99.9% of DNA is identical in every human being, but .01% is enough to distinguish between people. It is most commonly used in criminal cases to link a criminal to his/her crime scene, but is also used for paternity/maternity tests, and immigration records. Usually a skin, hair, or body fluid sample is collected from a crime scene or criminal or test candidate, then DNA is extracted and cut using enzymes that recognize patterns in DNA and run through a gel by an electric current in a process called electrophoresis (Annely).

Throughout history physicians have faced numerous ethical dilemmas and as medical knowledge and technology have increased so has the number of these dilemmas. Organ transplants are a subject that many individuals do not think about until they or a family member face the possibility of requiring one. Within clinical ethics the subject of organ transplants and the extent to which an individual should go to obtain one remains highly contentious. Should individuals be allowed to advertise or pay for organs? Society today allows those who can afford to pay for services the ability to obtain whatever they need or want while those who cannot afford to pay do without. By allowing individuals to shop for organs the medical profession’s ethical

In February 2003, 17-year-old Jesica Santillan received a heart-lung transplant at Duke University Hospital that went badly awry because, by mistake, doctors used donor organs from a patient with a different blood type. The botched operation and subsequent unsuccessful retransplant opened a discussion in the media, in internet chat rooms, and in ethicists' circles regarding how we, in the United States, allocate the scarce commodity of organs for transplant. How do we go about allocating a future for people who will die without a transplant? How do we go about denying it? When so many are waiting for their shot at a life worth living, is it fair to grant multiple organs or multiple