Blood Glucose Regulation

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LABORATORY REPORT
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Activity:
Name:
Instructor:
Date:

Blood Glucose Regulation
Sandra Shakur
January 25, 2015

Predictions
1. Plasma glucose levels will be highest immediately after the meal (0 hr).
2. Plasma ketone levels will be highest
1-3 hours after the meal.
3. Plasma insulin levels will be highest before the meal (fasting).
4. Plasma glucagon levels will be highest before the meal (fasting).

Materials and Methods
1. Name the Dependent Variable. plasma levels of glucose, ketones, insulin, and glucagon
2. Name the Independent Variable. food and beverage intake
3. Name the Controlled Variables. gender, age, BMI; physical activity, caffeine and alcohol intake
4.
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If values are similar for several time points, then give range of times when plasma insulin/glucagon concentration was highest.
1 hour post meal was when the insulin/glucagon concentration was the highest.
6. When was plasma insulin/glucagon concentration lowest? If values are similar for several time points, then give range of times when plasma insulin/glucagon concentration was lowest.
Fasting was when the insulin/glucagon concentration levels were the lowest

Discussion
1. Explain how insulin changed plasma glucose concentration over the course of the experiment.
Insulin changed the plasma glucose levels by raising them from the fasting to 1 hour mark but reduced down at hour 3 to almost the same level as fasting.
2. Explain how glucagon changed plasma glucose concentration over the course of the experiment.
When glucagon was at it's lowest, plasma concentration was at its highest. As glucagon levels came down so did the plasma glucose levels.
3. Explain what caused the change in plasma ketone concentration over the course of the experiment.

Ketones were high during fasting and low after eating because they were needed at first to generate ATP.
4. Explain how negative feedback caused the changes in plasma insulin concentration observed during the experiment.
Blood glucose controls secretion of glucogen and insulin through negative feedback.
5. Explain how negative feedback caused the changes in plasma glucagon concentration observed during the experiment.
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