Blood Transfusion And Transfusion Related Acute Lung Injury

1869 Words May 25th, 2015 8 Pages
Introduction:
Blood transfusion aims in appropriate use of blood and blood products in a safe manner to treat a condition leading to a significant morbidity and mortality which cannot be treated or managed by other treatment measures. However transfusion always carries a risk of triggering adverse reactions as well as transmission of blood borne infections1. Due to this the concept of patient blood management is gaining increasing attention worldwide and Hospital Transfusion Committees (HTC) has been created in different hospitals worldwide to monitor this. The major concern related to mortality by allogenic blood transfusion includes:
• Transfusion related acute lung injury (TRALI)
• ABO and non-ABO haemolytic transfusion reactions
• Transfusion associated sepsis
In addition to this several recent studies have shown an increase in mortality after cardiac surgery which involves blood transfusion2. Other than this the transmission of HIV virus and hepatitis C virus has been a major cause of concern for the society3.
The key to successful blood transfusion is dependent of multiple factors such as education, recruitment and adequate selection of blood donors followed by collection, processing and storage of blood and blood products, performance of serological and other specific tests at the collection facility before the transfusion and then transportation of this tested blood to the recipients as per their need4. Thus it is very crucial to have a proper management of this…
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