Bone Marrow Aspirate Research Paper

1. Which of the following anemias is caused by a failure of the bone marrow to produce red blood cells and may be congenital or acquired?

Acute Lymphoblastic Leukemia, is the disease that affects children the most and because of the abnormal cells that are immature white blood cells which cannot help the body fight infections cause children with the disease to often get infections and have fevers (National Cancer Institute, 2002, p. 1). The symptoms that the patient with ALL may have depend on the number of abnormal cells of the patient where exactly the cells collect. Children patients with ALL have low amounts of healthy red blood cells and platelets, which cause less oxygen to be carried through the body because of the lack of red blood cells. Patients at times may look pale, feel weak, and tired causing bleeding and bruising very easily because of their lack of enough platelets. This condition is called anemia. Anemia is very much common in patients with acute lymphoblastic leukemia. Fever, fatigue, bone or joint pain, tiny red spots under the skin called petechiae are a couple of symptoms that the disease ALL has. Headaches with, or without vomiting also may occur if patient happens to have abnormal cells collecting in the brain or spinal cord (National Cancer Institute, 2002 para. 2).

As I approached the Galaxy Rooms for the Bone Marrow Drive, I strongly felt that my commitment of time for this task would be profitable and satisfying. I had learned about the Bone Marrow Drive through the UTD Office of Student Volunteerism, and I hoped to experience something fulfilling. When the time came to register at the door, the staff treated me politely. They also clearly gave the necessary directions for filling out paperwork and other necessities. When the time came to get the cotton swab, the staff allowed me to do it myself! Thus, this decision greatly increased my comfort and allowed the overall drive to speed up as well. After about twenty minutes, I had gone through the process and became registered as a Bone Marrow Donor! Even

Also known as normocytic anemia. This is the most frequent type of anemia most often happening to males over 85 years old. It is a common problem that occurs to men and women over 85 years old. Symptoms include and are caused by: a reduced production of normal-sized red blood cells even though presence of hemoglobin in the red blood cells is within the standard range; an increased production of HbS as is seen in sickle cell diseases; greater destruction and loss of red blood cells; an increase in plasma volume that is not compensated by anything else; a B2 (riboflavin) deficiency; and a B6 (pyridoxine) deficiency. (Brill & Baumgardner 2000).

The organism is usually found in the cell in a particular category of white blood cells with

Methemoglobinemia can be either acquired or congenital. When methemoglobinemia is acquired the mechanism that reduces methemoglobin is not able to keep up with the amount of oxidation that is occurring due to the various methods of acquiring methemoglobinemia [2]. There are two primary reasons for congenital methemoglobinemia; either there is a presence of an abnormal structure of the hemoglobin molecule, called hemoglobin M, or a deficiency in the enzymes cytochrome b5 methemoglobin reductase or glucose-6-phosphate dehydrogenase (G6PD) [5]. There are two main types of congenital methemoglobinemia, type I and type II. Type I methemoglobinemia is where the enzyme deficiency only affects the erythrocytes, and is easily

Every year, thousands of people of all ages are diagnosed with leukemia and other life-threatening diseases. Many of them will die unless they get a bone marrow or cord blood transplant from a matching donor. Seventy percent of people do not have a matching donor in their family and depend on the Be The Match Registry to find a match to save their life. The National Marrow Donor Program, which operates Be The Match, is an Institute Award for Excellence winner (Balanced Scorecard Institute, 2016). But. The not-for-profit organization matches patients with donors, educates healthcare professionals and conducts research so more lives can be saved. During the summer of 2006,

Anemias: Laboratory Findings for Client who has Aplastic Anemia (System Disorder, RM AMS RN 9.0 Chp 41)

Myeloproliferative Neoplasms are caused due to an increase in the red blood cell production (a mutation in the JAK2 gene)

Myeloproliferative and myelodysplastic syndromes, two diverse groups of bone marrow disorders, are respectively characterized by an overproliferation or ineffective production of various blood cells. The clinical laboratory plays a prominent role in the diagnosis and classification of myeloproliferative and myelodysplastic disorders, each of which presents a unique set of morphologic, pathophysiologic, and genetic traits. The contemporary diagnosis and categorization of these syndromes emphasizes a combination of hematologic bone marrow characterization and gene mutation studies.

overproduction of megakaryocytes in the bone marrow. This means the platelets number increase in the peripheral blood and it is called Thrombocythemia. This disorder is called essential because the increase in platelets number is a distinctive problem of the blood cell production in the bone marrow (Rumi et al., 2014).

Cytogenic analysis – Microscopic examination of lymphocytes to look for structural changes or changes in number of chromosomes.

In a hypertonic solution, the red blood cells will shrink and be destroyed, as water diffuse out of them.

These cells' cytoplasm is rich in hemoglobin, an iron-containing biomolecule that can bind oxygen and is responsible for the blood's red color.

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