Bone Mineral Density – Osteoporosis
Osteoporosis is a skeletal disease that affects millions of people worldwide. It is characterised by a low bone mineral density (BMD) and deterioration of bone tissue and strength. This in turn increases bone fragility and its susceptibility to fracture and other injuries. Bone remodelling is the process of continuous bone reabsorption and rebuilding; however, osteoporosis occurs when there is not enough bone formation and/or an excessive amount of bone reabsorption. Many non-invasive techniques exist to measure BMD, all which play an important role in the diagnosis and progression of osteoporosis.
Anatomical Tool 1: Quantitative ultrasound (QUS)
Quantitative ultrasound (QUS) is a recently discovered
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T. T., Khan, N. C., Lam, N. T., Mai, L. B., Le, D. N., Nhung, B. T., . . . Yamamoto, S. 2005). QUS was used due to its low cost, high accessibly and no exposure to radiation. After the study was completed it was found that QUS was an effective way to measure this large group with minimal consequences.
Study Three:
One factor that had not been investigated was whether the variables of QUS were as affected by clinical risk factors as axial BMD measurements obtained by using the DXA method. A study was conducted to compare the calcaneal QUS and axial BMD T and Z scores in a large group of women (specifically 1115 pre- and postmenopausal women). Some of these women had no clinical risk factors whilst others had one or more risk factors for osteoporosis. (Frost, M. L., Blake, G. M., & Fogelman, I. (2001)). They investigated measurements at the calcaneus using QUS and at the lumbar spine and hip using DXA and found that the variable of QUS were affected to the same extent as axial BMD measurements using the DXA method. This important finding could become critical in the standardisation of QUS in clinical practice.
Anatomical Tool 2: Duel-energy X-ray absorptiometry (DXA)
Duel-energy X-ray absorptiometry (DXA) utilises x-rays of two difference energies to produce an image of the region of interest. This image is projected and then used to calculate and determine
The management of osteoporosis patients start with the diagnosis by rolling out secondary causes and then confirm it by measuring bone mineral density (BMD). After that, begin the treatment with lifestyle changes, pharmacological medications, and surgery for some fractures if needed. In this essay I will cover generally the diagnosis, treatment, and prevention of osteoporosis in five steps.
As generally stated in the introduction, osteoporosis is a skeletal disorder that involves the strength and integrity of one’s bones. The WHO defines osteoporosis as, “a systemic skeletal disorder characterized by low-bone mass, deterioration of bone tissue, increased bone fragility, and its susceptibly to recurrent fractures.” 2 The most important factor to take into account when addressing osteoporosis is the mass of bone, also referred to as, bone mineral density (BMD). As bone mass begins to decline, typically in the older population, specifically postmenopausal women, individuals are at an increased risk for fractures.3 As a result of this serious condition, many people are affected by morbidity, mortality, and economic difficulty.1
Osteoporosis is a disease in which bone tissue is normally mineralized but the mass of bone is decreased and structural integrity of trabecular bone is impaired. Cortical bone becomes more porous and thinner, making bone weaker and prone to fractures. The World Health Organization (WHO)(1994) has defines postmenopausal osteoporosis abased on the bone density. Bone density is based on the number of standard deviations away from the mean bone mineral density of a young adult reference population, a T-score. Normal bone mass density is 0 to -.99 standard deviations, low bone density (osteopenia) is -1.0 to -2.49 standard deviations, osteoporosis is labeled as less than or equal to 2.5 standard deviations, and severe osteoporosis is less than or equal to 2.5 standard deviations and included a bone fracture.
(Kling, J. M., Clarke, B. L., & Sandhu, N. P., 2014, p. 567). Osteoporosis risk factors
Osteoporosis is an age related disorder, more common in females compared to males. Osteoporosis is defined as a “skeletal disorder characterized by compromised bone strength predisposing to increased risk of fractures (Manolagaas, 2014). Osteoporosis is defined as “a disease characterized by low bone mass and deterioration of bone tissue (What is osteoporosis?2014). Osteoporosis is sometimes also referred as “silent thief” as the bone loss occurs very slowly and silently without any symptoms (Osteoporosis facts & statistics.2014). The most common site for fracture due to osteoporosis is hip followed by humerus (Woltman & den Hoed, 2010) . Osteoporosis can occur at any age, although it is a disorder common in females (especially post-menopausal females). Everyone is prone to osteoporosis (Osteoporosis facts & statistics.2014). According to Osteoporosis Canada, 1 in 3 Canadian females and 1 in 5 Canadian males may suffer fractures due to osteoporosis during their lifetime (Osteoporosis facts & statistics.2014). Canadian health care system spends 1.2 billion dollars for the acute hospitalization caused by osteoporosis and in 2010 the health care system spent 3.9 billion dollars for the total treatment of osteoporosis (Osteoporosis facts & statistics.2014). Osteoporosis can be screened and diagnosed by various methods; however the dual energy x ray absorptiometry (DXA) is commonly used. If the T-score values are less than -1 and greater than -2.5SD it is termed as osteopenia,
Osteoporosis is a disease of bone that leads to an increased risk of fracture. In osteoporosis the bone mineral density (BMD) is reduced, bone microarchitecture is disrupted, and the amount and variety of non-collagenous proteins in bone is altered. Osteoporosis is defined by the World Health Organization (WHO) in women as a bone mineral density 2.5 standard deviations below peak bone mass (20-year-old healthy female average) as measured by DXA; the term "established osteoporosis" includes the presence of a fragility fracture.[1] Osteoporosis is most common in women after menopause, when it is called postmenopausal osteoporosis, but may also develop in men, and may occur in anyone in the presence of particular hormonal
The purpose of my report is to recommend, everyone older than 45 years old and up , the need to see a doctor and start to check their bone density periodically in order to lower the risk to get osteoporosis. In case that osteoporosis has been found in the patient, guide him or her to find the best way to revert it to anterior state , if it were possible.
Osteoporosis is referred to as the decrease in bone density and mass over time. The interior bones become progressively weaker and can cause a stooped posture. This makes the individual more susceptible to bone fractures. Osteopenia regards a condition where the bone material density is considered lower than normal. This is usually a precursor to the musculoskeletal disorder, known as osteoporosis. The term ‘osteoporosis’ means ‘porous bones’. In this case, bone is a living tissue that is continuously being broken down and replaced. Thus, osteoporosis happens when the creation of bone does not keep up with the removal of the old bone. In this disorder, the bones are diminished and deteriorated in structure. This condition is typically prevalent in older women due to an estrogen deficiency with menopause. The lack of estrogen increases bone resorption and decreases bone deposition. In addition, osteoporosis can occur with atrophy, which is caused by disuse. Additionally, osteoporosis can occur in men due to the aging process as well as patients who have received corticosteroids, which are hormones used to treat inflammatory conditions.
Huether & McCance (2012) state that bone density is based on an individual’s T score, which is a score that measures bone mineral density. Usually the range of a healthy individual’s T score is anywhere between 0 and 2.5, with a score greater than 1, but lower than 2.5 an individual is conserved to have low bone density, with a score greater than 2.5, the individual is considered osteoporotic (Huether &McCance, 2012). Bones are supposed to be strong and support daily activities, and when bones become too weak to support functions the body undergoes, complications arise.
Osteoporosis is an imbalance between bone loss and bone remodeling. Basically the bone density has become extremely low causing much pain and a higher chance of fractures and or bone breakages. Bone remodeling is responsible for removing mature bone tissue and replacing it with new bone tissue. This disease is more common in older adults, Asians, and Hispanics due to the lack of calcium consumption. Women are often more prone to getting osteoporosis than men because women are born with less bone mass than men. This disease often occurs if full bone mass was not achieved during the bone-building years.
Background: Osteoporosis is the most common bone disease and is characterized by low bone mass, deterioration of bone tissue and disruption of bone architecture, compromised bone strength, and an increase in the risk of bone fracture. The World health organization (WHO) defines osteoporosis as having a bone mineral density (BMD) at the hip or the lumbar spine of less than or equal to 2.5 standard deviations below the mean BMD of a young-adult reference population. Based on data from the National Health and Nutrition Examination Survey III (NHANES III), NOF has estimated that more than 9.9 million Americans have osteoporosis and an additional 43.1 million have low bone density.2 About one out of every two Caucasian women will experience an osteoporosis-related fracture at some point in her lifetime, as will approximately one in five men.
Osteoporosis is characterized by low bone mineral density and the decay of bone fibers resulting in weaker bones; making bones deteriorated and vulnerable to fractures (Sharma and Khandelwal., 2010). Osteoporosis is a disease that affects men and women. According to a study half of the women and one-eighth of the men would suffer from bone fractures caused by osteoporosis during their life span (Anders, Tuner, and Freeman, 2013). Osteoporosis turns into a considerable health problem mainly for women after menopausal years; as women aged their Bone Mineral Density (BMD) decreases as the risks of bone fractures increase (Mendoza-Romo et al., 2014). Why are women at risk of developing osteoporosis? Bone health is directly
Within America, osteoporosis presently affects approximately 10 million people and is responsible for more than 1.5 million fractures annually (Societal Burden of Osteoporosis). About 54 million Americans have osteoporosis and low bone mass which makes them at high risk for the disease (NOF). This disease holds a substantial financial burden with annual direct cost ranging from 17 to 20 billion dollars. Because of the consistent growth in age among the population, the prevalence and number of osteoporosis fractures will continue to increase (SBO). Worldwide, osteoporosis has an estimated total of affecting 200 million women, one-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80, and two-thirds of women aged 90. Across the areas of Europe, United States,
Although common, osteoporosis in a disease that can be prevented to an extent with modified lifestyle choices including nutrition and exercise. When considering bone health, the
A large number of studies in the last decades, have confirmed the usefulness of QUS to predicte osteo¬porotic fractures of the calcaneus (particularly in elderly women aged 65-70 years or older), the distal metaphysis of the phalanx, the radius and the tibia (50).