Breast Cancer : Cancer And Cancer Essay

Triple-negative breast cancer occurs when cells lack estrogen receptors and progesterone receptors from not having an excess of the HER2 protein (Rosen, 2011). The gene HER2 helps cells grow, divide, and repair; this spreads the disease faster. HER2-positive breast cancer becomes a more aggressive cancer and has a higher risk for recurrence (Chen, 2010).Typically found in younger women and African-American women; this cancer grows and spreads quickly (Rosen, 2011).

Over the past decade breast cancer has become one of the most predominant diseases in the United States. Breast cancer starts out as a malignant tumor in the tissues of the breast which is formed from the uncontrolled growth of abnormal breast cells. Breast cancer is the most common cancer in women, but it can also appear in men. (Stephan, 2010)

It is estimated that 40,030 deaths from breast cancer (39,620 women, 410 men) are will occur in 2013. Breast cancer is second only to lung cancer as the leading cause of cancer deaths in women. Breast cancer death rates have been decreasing steadily since 1989, rates decreased by 3.0% per year in women younger than 50 and by 2.0% per year in women 50 and older between 2005 and 2009. This decline is attributed to prevention, early detection, improved healthcare services and reduced use of MHT.

According to the United States Breast Cancer Statistics (2016), in 2016 there will be an estimated 246,660 newly diagnosed cases of invasive breast cancer and 61,000 of non-invasive breast cancer among women. For this reason, when studying breast cancer based on a large-scale impact, it not only affects the patient themselves but, as well as their families and communities nationwide. Furthermore, many contributing factors lead to this being such a public health issue. Conclusively, there are specific programs, services, and policies that help to assist the contributing factors of such a public health threat. Nevertheless, breast cancer is still an increasing concern in society, and much-needed research is required to be able to detect and treat this disease.

Breast Cancer is a type of cancer where in the breast cells growth are uncontrolled. To enhance our understanding of breast cancer, knowing how any cancer can develop is crucial. Cancer develops as a result of the alteration of the genes, or abnormal changes in the genes accountable for managing the growth of the cells and maintaining their health. In each nucleus, the genes operates as the “control room.” The cells in our bodies replace themselves through a process called cell growth in which the

An effective breast cancer treatment in some women can be traced to the root of the disease. Some of the most aggressive form of breast cancers are caused by a transmembrane receptor protein known as Human Epidermal Growth Factor Receptor 2 (HER2) which is a member of the HER family of receptor tyrosine kinase. Approximately 20,000 HER2 receptor are normally expressed on surface of healthy breast cell however, in about 25% of breast cancer cells the HER2 protein is overexpressed resulting in tumour cells with as many as over 2 million receptors present on their surface. This cancer is known as HER2 positive (HER2+). The effect of HER2 overexpression is an increase in receptor mediated intracellular signalling causing the cell

As the cells change, it begins to divide rapidly causing a tumor to form. The term “breast cancer” refers to a malignant tumor that has developed from cells in the breast. Breast cancer can begin in different areas of the breast, or in some cases, the tissues in between. There are many different types of breast cancer, including non-invasive, invasive, recurrent, metastatic breast cancer, as well as the intrinsic or molecular subtypes of breast cancer. Human epidermal growth factor receptor 2 (HER2) is overexpressed in around 20-30% of breast cancer tumors. It is associated with a more aggressive disease, higher recurrence rate, and increased mortality.

Breast cancer constitutes the second most prevalent cancer most common among women of the world with an estimated 1.62 million reported cases in 2012 which constitutes 25% of all cancer cases and ranks fifth among mortality due to cancer (Ferlay et al., 2015). In the United States, according to American Cancer Society an

Breast cancer is the most common cancer in women. In 2008, more than one million women underwent a diagnostic evaluation for suspected breast cancer. Approximately 182,500 women of the more than one million that received an evaluation also received a positive diagnosis (Montgomery, 2010). Risk factors linked to Breast Cancer include: gender, age, family history, prior breast cancer, previous biopsy, race and ethnicity, breast density, and long menstrual history because of prolonged hormonal stimulation. Modifiable related risk factors also include hormone replacement therapy, alcohol, weight, and physical

Cancer of the breast is the most common type of non-skin cancer affecting women. It also comes second after lung cancer in the number of deaths among the African-American population in 2017; the American Cancer Society estimated that there would be approximately 252,710 new cases of breast cancer which is considered invasive that will be diagnosed in the United States. More so, nearly 63,410 new cases of (CIS) carcinoma in situ will be detected, and approximately 40,610 women will depart this life as a result of cancer of the breast(Siegel, Miller, & Jemal, 2015).In the United States, the incidence of cancer of the breast is not similar among the African America women and the white. Such that, it has been noted that the

This paper will inform you of Breast Cancer. It is the most common form of cancer in women today but thanks to medical advances it is no longer the number one killer of women.

Treatment failure is not uncommon with 30% of breast cancer patients having no improvement following current treatments (Lendorf et al., 2011). A better understanding of the genomic and biological patterns associated with breast cancers may provide the key to improving diagnosis as well as management and treatment of this disease.

Breast cancer exists today as a vicious disease which has multiple facets for killing its host. The largest indicator of survival rate is length of time alive after diagnosis with the disease, and then whether or not the disease has metastasized to a new location in the body. For breast cancer patients, the 5-year survival rate of patients below Stage 4 is 90%. The stages below the 4 stage represent the stages where the breast cancer has not metastasized into other regions of the body. When breast cancer metastasizes into another region of the body, the 5-year survival rate of these individuals drops to 22%. The most common places of metastasis include the brain, liver, and lungs. The goal of studying cell line 231BR is that of

Breast cancer is the most common type of cancer in women, it accounts for one of every three diagnoses in the United States. Breast cancers are malignancies, life threatening tumors that develops in one or both breasts.

According to the American Cancer Society, Each year, more than 200,000 women are diagnosed with breast cancer; furthermore Twelve percent of all women will contract the disease, and 3.5% of them will die from breast cancer (American Cancer Society, 2005). There are risk factors that may lead to breast cancer. There are 4 stages of breast cancer and several treatments, although treatments vary from types and stages of breast cancer. Breast cancer is the leading cause of death among women who are 40 to 55 years old (Breast Cancer, 2009).Cancer occurs when cells divide uncontrollably. It changes from a normal cell to cancerous cells that require gene alterations. Therefore the altered genes and the uncontrolled growth may lead to tumors.