Breast Cancer : Cancer And Cancer Essay

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Internationally, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer related death amongst women. (CITE) Each year an estimated 1.7 million new cases are diagnosed worldwide, and more than 500,000 women will die of the disease. (CITE) According to (CITE), somewhere in the world one woman is diagnosed with breast cancer every 19 seconds and more than three women die of breast cancer every five minutes worldwide. (CITE) Breast cancer is a heterogeneous condition that contains more than 20 different subtypes. (ALC) These various subtypes are grouped based upon the genes in which they express. This includes the genes for the estrogen receptor (ER), progesterone receptor (PR), and HER-2 receptor, all of which influence cell growth rate and the metastatic potential of cancer cells. (CITE)[8, 9 ALC] The purpose of this paper is to explore XYZ of the HER-2 positive breast cancer subtype. Approximately one in five women diagnosed with breast cancer worldwide will have HER-2 positive breast cancer, a notably aggressive form of the disease. In the United States alone XYZ women were diagnosed with HER-2 positive breast cancer in ABC. (CITE) Poor prognosis for patients with breast cancer is dictated by tumor characteristics including high grading (poor differentiation), large tumor size, and lymph node involvement. According to XYZ, HER-2-positive breast cancers tend to be larger, high grade tumors and are more likely to spread to other organs in the

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