Breast Cancer Essay

triple negative breast cancer subgroup (n=23) and its relation to the pathological response were evaluated. The

Attention getter: About 85% of breast cancers occur in women who have NO (make sure to emphasize) family history of breast cancer. This disease occurs mainly in women but men can also get it.

Age: Breast cancer incidence increases with age, it doubles about every 10 years until the menopause, after which the rate of increase slows dramatically.

Breast Cancer is a type of cancer where in the breast cells growth are uncontrolled. To enhance our understanding of breast cancer, knowing how any cancer can develop is crucial. Cancer develops as a result of the alteration of the genes, or abnormal changes in the genes accountable for managing the growth of the cells and maintaining their health. In each nucleus, the genes operates as the “control room.” The cells in our bodies replace themselves through a process called cell growth in which the

Breast cancer is a disease in which certain cells in the breast become abnormal and multiply uncontrollably to form a tumor. Breast cancer is the second most commonly diagnosed cancer in women. (Only skin cancer is more common.) About one in eight women in the United States will develop invasive breast cancer in her lifetime. Researchers estimate that more than 230,000 new cases of invasive breast cancer will be diagnosed in U.S. women in 2015. Cancers occur when a buildup of mutations in critical genes—those that control cell growth and division or repair damaged DNA—allow cells to grow and divide uncontrollably to form a tumor. Breast cancer can be caused by inherited genetic factors. These genetic

Another factor that contributes to the development of breast cancer is actually the hormone estrogen. This seems unusual because estrogen is a hormone that is essential to the bodies of women in various ways. Estrogen is necessary for normal growth and development of breasts and reproductive organs, as well as for the maintenance of a healthy heart and bones. However, lifetime estrogen exposure may increase a woman’s risk of developing breast cancer. It does not actually produce the mutation in the DNA, nevertheless Estrogen stimulates the proliferation of breast cells that already contain a mutation. These mutated cells will continue to reproduce and have an increased chance of becoming cancerous.

As the cells change, it begins to divide rapidly causing a tumor to form. The term “breast cancer” refers to a malignant tumor that has developed from cells in the breast. Breast cancer can begin in different areas of the breast, or in some cases, the tissues in between. There are many different types of breast cancer, including non-invasive, invasive, recurrent, metastatic breast cancer, as well as the intrinsic or molecular subtypes of breast cancer. Human epidermal growth factor receptor 2 (HER2) is overexpressed in around 20-30% of breast cancer tumors. It is associated with a more aggressive disease, higher recurrence rate, and increased mortality.

“In 2015, there are more than twenty-eight million women with a history of breast cancer in the United States of America. This Includes women currently being treated and women who have finished treatment. – BreastCancer.Org“ Breast cancer has taking over many people bodies, also lives. Anybody can get breast cancer from man to women. Cancer doesn’t have to be in your family history for you to get it.

Mind benign breast malfunction can also increase the chances of having breast cancer in later stages of a woman/s life. Irradiation at early age also increases risks of getting breast cancer.

Subsequently, each cell that develops from the fertilized egg will receive this mutated gene. He states that for a cancer to manifest, two mutations must occurs. In hereditary cancers, the person inherit one mutant gene. The second mutation occurs as result of a mitotic error during the many cell division that occurs in the person's lifetime. In sporadic cases both mutation occur in the person's lifetime. In sporadic cases both mutation occurs after fertilization an are acquired much later in life. From this Kudson conclude that hereditary cancers manifest at younger age and there is a higher incidence of multiple tumors, where sporadic cancers occur late in the life and usually only a single tumor occurs. The principal causes of cancer appears to be environmental agents. A good example of this is skin cancer. The condition has increased among fair skinned people who expose themselves to too much sunshine, while being very uncommon among dark skinned races (knudson 1971, cited in Ormiston, 1995). Therefore, most genetic alteration are acquired through our life time from environmental carcinogens with only a small percentage been inherited. However, inherited cancers are very important as it appears that the genes responsible for, hereditary cancer maybe the same as those involved in sporadic malignancies.

Breast cancer constitutes the second most prevalent cancer most common among women of the world with an estimated 1.62 million reported cases in 2012 which constitutes 25% of all cancer cases and ranks fifth among mortality due to cancer (Ferlay et al., 2015). In the United States, according to American Cancer Society an

The reason why I am touching on this subject is because breast cancer is the most common disease that affects women across the United States. This is known as the leading cause of death in women between the ages of 30 and 40, but some can happen in their 20s. Statistics show “According to the National Cancer Institute, one in eight women who live to be age 80 will develop breast cancer in her lifetime. This makes the disease the second most commonly diagnosed cancer among American women, after skin cancer.” (www.cancer.gov) Breast cancer is a lump found in the breast in which cells become abnormal and multiply uncontrollably, forming a tumor. Malignant cells begin to spread if untreated to original tumor which causes inflammation in the breast

# Sex: Breast cancer is mostly diagnosed among women with an average of 37 newly diagnosed cases each day. The incidence of breast cancer is very low in men due to less development of breast tissue and minimal or no exposure to tumour promoting female hormones.

According to the American Cancer Society, Each year, more than 200,000 women are diagnosed with breast cancer; furthermore Twelve percent of all women will contract the disease, and 3.5% of them will die from breast cancer (American Cancer Society, 2005). There are risk factors that may lead to breast cancer. There are 4 stages of breast cancer and several treatments, although treatments vary from types and stages of breast cancer. Breast cancer is the leading cause of death among women who are 40 to 55 years old (Breast Cancer, 2009).Cancer occurs when cells divide uncontrollably. It changes from a normal cell to cancerous cells that require gene alterations. Therefore the altered genes and the uncontrolled growth may lead to tumors.

Although breast cancer may occur at a higher rate in older women; everyone should know their family cancer history. For instance, genetics can play a role in developing this disease, as well as some inherited genes. Additionally, having a family history of breast cancer can double the risk of