Breast and Ovarian Cancer Essay

When I was given this ancestry project I automatically knew I wanted to figure out my family genetics and why I got cancer in the first place. I am the only child out of four in my family to get cancer. After digging into some history I found out that my mom, grandma, and uncle had cancer. It's weird how genetics work but I was basically doomed from the beginning. My grandma had breast cancer and had both her breasts removed. My uncle had stage four lung cancer and passed away shortly after diagnosis. And my mom had thyroid cancer only a few years ago and is a survivor. Since there is history of breast cancer in my family I had to get tested for the BRCA1 and BRCA2 gene, which is a mutated gene that is inherited from your family. This gene increases your risk of developing breast cancer to 50%, a one in two

Over the past decade breast cancer has become one of the most predominant diseases in the United States. Breast cancer starts out as a malignant tumor in the tissues of the breast which is formed from the uncontrolled growth of abnormal breast cells. Breast cancer is the most common cancer in women, but it can also appear in men. (Stephan, 2010)

Age: Breast cancer incidence increases with age, it doubles about every 10 years until the menopause, after which the rate of increase slows dramatically.

Breast can be intervened if caught on at an early stage. The problems encountered with breast cancer is that some women are not taking proactive measures to detect early indications of cancer, through clinical breast self-examination

Generally speaking, throughout the United States, Cancer is a public health concern that has a significant impact amongst both men and women. At the same time, Breast Cancer indicates development of a tumor from cells in the breast known as a malignant tumor. Breast Cancer can begin at two different points, either the cells of the lobules, that are milk-producing glands, or the ducts, a channel draining milk from the lobule to the nipple (“What is Breast Cancer,” 2016). Specifically speaking about Breast Cancer among women, according to the Center for Disease Control and Prevention (2016), it is the most common cancer, regardless of ethnicity or race. Under those

Women who are at the greatest risk are over the age over the age of fifty years of age. Patients with a family history of cancer, especially in their first degree relatives, may have inherited mutations of BRCA1 and/or BRCA2. BRCA1 and BRCA2 are genetic mutations that put patients are risk for cancer. Patients that have a history of breast cancer are five times more likely of developing cancer in the opposite breast. Patients with dense breast are at risk for developing breast cancer due to the fact dense breast contains more glandular and connective tissue. Patients who are exposed to high doses of ionizing radiation to the thorax, early menarche, tobacco use, nulliparity, late menopause, and first child birth after thirty years of age put the patient at risk for breast cancer (Ignatavicius, 2013, p.

Despite significant advances in research, Breast Cancer is still the most common cancer, affecting both men and especially women. In the US, 232, 670 new cases of invasive breast cancer were expected to be diagnosed along 62,570 new cases of non-invasive breast cancer in women and about 2,360 new cases of invasive breast cancer were expected to be diagnosed in men in just 2014 .

There are many different diseases that terrorize the human race every day. Of all of these sicknesses, one of the most devastating is breast cancer. Breast cancer touches all types of people all over the world each day. It is actually the second most common cancer amongst women in the United States. One in every eight women in the United States has some form of breast cancer and currently, the death rates are higher than any other cancer with the exception of lung cancer. Cancer is defined by the Merriam-Webster Online dictionary as “a malignant tumor of potentially unlimited growth that expands locally by invasion and systemically by metastasis.” Therefore, breast cancer is a disease of

By helping to repair DNA, the BRCA2 protein plays a critical role in maintaining the stability of a cell 's genetic information. The cancer risk caused by BRCA2 mutations is inherited in a dominant fashion, even though usually only one mutated allele is directly inherited. This is because people with the mutation are likely to acquire a second mutation, leading to the dominant expression of the cancer. A mutated BRCA gene can be inherited from either parent. Because they are inherited from the parents, they are classified as hereditary or germline mutations. Because humans have a diploid genome, each cell has two copies of the gene (one from each biological parent). Typically only one copy contains a disabling, inherited mutation, so the affected person is heterozygous for the mutation. If the functional copy is harmed, however, then the cell is forced to use alternate DNA repair mechanisms, which are more error-prone. The loss of the functional copy is called loss of heterozygosity (LOH). Any resulting errors in DNA repair may result in cell death or a cancerous transformation of the cell.

All around the world, breast cancer has become a huge issue and has effected many lives.

Breast cancer can be acquired in many different ways. Genetics, gene mutations (5-10%) and risk factors including age,

Breast Cancer affects one in eight of American women, and is the second most common cause of cancer death in America. I chose to write my term paper on breast cancer because it is a disease that has effected some members of my family. Due to this possibly inherited condition, I felt that researching the topic would help me learn ways to prevent the disease and educate myself to perform self-exams that may result in early detection.

They analyzed the genetic profiles of these patients to study a concept known as the “double-hit hypothesis”, which is a widely accepted theory in the field of cancer.

There are lost of ways to prevent cancer or try to prevent it. One of these is reducing your fat intake. One study shows that the result of this is that the level of estrodiol, the potent form of estrogen decreases. Another way to fight breast cancer is to eat plenty of fruit and vegetables. Many fruits and vegetables contain chemicals that may be cancer fighters. A concentrated form of limonene, a substance found in citrus skins, has been found to shrink breast cancer in animals. Some studies have shown that if you breast-fed for more than four months it lowers your risk of the cancer. In a recent study women who have underwent breast reduction have a low risk of getting breast cancer by forty percent.

Breast cancer accounts for one third of all new cancer diagnoses in the United States (Cauley, et al., 2007). The first sign in the process of this disease is a lump that forms around the breasts. For this reason, it is necessary to get the yearly mammograms once a woman reaches a certain age. Also, monthly self-examinations can aid in finding breast cancer early. If this condition is found early enough, chances of survival are abundant. Most women who get breast cancer are older than 50 with 86% of the deaths occurring in this age group (Cauley, et al., 2007). Postmenopausal women have a higher risk for breast cancer, because the risk increases when levels of endogenous estradiol rise (Cauley, et al., 2007). Breast cancer is the most common cancer that occurs in women. This epidemic has a higher incidence rate among white women than in African American women, but African American women have a higher mortality rate (Breast Cancer Risk Factors, 2010). White women are more apt to develop this disease than any other ethnicity. However, in women under 45, breast cancer is more common in African American women (Breast Cancer Risk Factors, 2010).