Bronchial Asthma And Chronic Inflammatory Disorder Of The Airways That Involves A Complex Interaction Of Airflow Obstruction, Bronchial

Asthma itself is an inflammatory disease characterized by increased airway responsiveness due to a variety of stimulus. The inflammation causes the hyper-responsiveness than in turn causes bronchiolar smooth muscle constriction, resulting in obstruction of airflow. Some

To better understand the impact of asthma, a brief overview of the causes (aetiology) and disease progression (pathophysiology) must be shown. As common as asthma is, not much is known about its aetiology, according to findings presented by Subbaroa, Mandhane and Sears (2009, pg. 181-187) in a review from the Canadian

Asthma is a chronic inflammatory disorder of the bronchial mucosa and hyperreactive bronchial tubes. Its etiology has been linked to both genetic and environmental factors. Several genes, including those that influence the production of proteins and cells involved in the immune response (such as interleukins, eosinophils, mast cells) have been linked with asthma. A decreased number of T-regulatory cells is also associated with asthma. Environmental factors linked with asthma include exposure to allergens, urban residence, and smoking (or exposure to secondary smoke). Recurrent respiratory tract viral infections may also contribute to the development of asthma. Decreased exposure to certain infectious organisms during early childhood, and the consequent underdevelopment of the immune response, can also lead to the development of asthma--this is known as the hygiene hypothesis (McCance & Huether, 2014, p. 1263-4).

Asthma is a respiratory disease that many people deal with every single day. “According to World Health Organization, approximately 180,000 people die from asthma each year.” (Jardins and Burton 187) Most people never think of asthma as a life threatening disease, but it can be crucial. As the number of people with asthma increases, the more likely you are to come in contact with someone who has been diagnosed with this disease. Asthma is a severe breathing problem that has many complications that is dealt with daily like shortness of breath, chronic cough, tightness of the chest and shortness of breath, my main focus is childhood asthma, allergic asthma, and medication to treat asthma.

The purpose of this paper is to describe the pathophysiology of chronic asthma and acute asthma exacerbation, with explanation of arterial blood gas pattern during an asthma exacerbation. Also, explain how ethnicity might impact pathophysiology of asthma and asthma exacerbation. The diagnosis and treatment plan needed to relieve the presented signs and symptoms will be reviewed. Lastly, constructs two mind maps for chronic asthma and asthma exacerbation including its epidemiology, pathophysiology, clinical presentation, diagnosis and treatment.

Asthma is a chronic condition affecting the respiratory system and has a considerable impact on both individuals and a population. Everybody is susceptible to asthma, some more than others, depending of a variety of factors including, age, sex, geographical location and income. Asthma is particularly prevalent in younger children and the elderly and while it can be fatal, most people have mild cases of asthma that are relatively easy to treat. The condition mainly impacts an individual’s physical ability to contribute to a community.

Serious respiratory diseases such as Chronic Obstructive Pulmonary Disease (COPD), including chronic bronchitis and emphysema, are a leading cause of morbidity and death worldwide. Asthma, a chronic disease that involves inflammation of the airways, bronchoconstriction, and intermittent (usually reversible) airflow obstruction, also affects numerous individuals worldwide. Both COPD and asthma are common obstructive lung disorders that affect over 49 million people in the US (1). While the pathology of asthma and COPD are distinct, both diseases share some features. Asthma is often a childhood disease, but some patients manifest symptoms or develop the disease as adults.

Asthma, as defined by the NIH, “is a chronic lung disease that inflames and narrows the airways. Asthma causes recurring periods of wheezing (a whistling sound when you breathe), chest tightness, shortness of breath, and coughing.” (National Institutes of Health, National Heart, Lung and Blood Institute [NHLBI], 2015). There are risk factors that may predispose a child to developing asthma, which include having allergies, eczema, and/or having parents who have asthma. Asthma is not a disease that is preventable. (NHLBI, 2015). The risk or likelihood that someone would have asthma is based on the biological makeup of the individual that would predispose them to the disease, rather than behavioral, environmental, or even social factors.

Asthma is a chronic condition. While there is no cure, you can work with your doctor to manage it. It is very important to know how asthma affects the lungs, even if you have had asthma for a while. Learning more about asthma signs and symptoms can help.

Allergic Asthma or allergy-induced asthma is one of many forms of asthma. Asthma is a chronic lung condition that results in recurring episodes of a difficult problem breathing. According to Asthma and Allergy Foundation of America(aafa), about 25 million Americans have some form of asthma. Breathing is a basic essential part of life which is normally done without thinking about it. The people with asthma airway may become inflamed and constricted due to allergens, irritants, physical activities and/or respiratory infection. The symptoms of this chronic condition may vary in the individual person. Some symptoms are coughing, wheezing, shortness of breath, and chest tightness.

Asthma is a chronic airway disorder marked by inflammation. The inflammation affects multiple structures involved in the respiratory system of the body. These structures include the trachea, the bronchi, and the bronchioles. Bronchoconstriction is the main response that occurs during an asthma attack. The bronchoconstriction can be attributed to many different factors including edema, an excessive amount of mucus, muscle damage and bronchospasms. Bronchospasms are “… sharp contractions of bronchial smooth muscle” (Lynn & Kushto-Reese, 2015). The muscle damage can lead to severe airway impairment and a perforated epithelium which then allows easy entry of the allergens and triggers.

Asthma is a chronic lung disease characterized by episodes in which the bronchioles constrict due to oversensitivity. In asthma, the airways (bronchioles) constrict making it difficult to get air in or out of the lungs. Breathlessness is the main symptom. The bronchi and bronchioles become inflamed and constricted. Asthmatics usually react to triggers. Triggers are substances and situations that would not normally trouble an asthma free person. Asthma is either extrinsic or intrinsic. Extrinsic is when the inflammation in the airway is a result of hypersensitivity reactions associated with allergy (food or pollen). Intrinsic asthma is linked to hyper responsive reactions to other forms of

%) 0(0 %) 3 Asthma is a communicable disease. It spreads from one person to another. 197 (65.7) 64(21.3) 35(11.7%) 4 Do you know asthma is caused by a combination of genetic and environmental factor 118(40.7% 90(30% 53(17.7%) 5 Do you know the main symptoms (coughing, wheezing, shortness of breath, chest congestion) 189(63% 63(21% 48(16%) 6

The pathophysiology of Asthma includes inflammation of the airway. The way in which this works is from an irritant which can include dust, pollen, cedar, or cat hair. When a reaction occurs, the airways become inflamed and narrow. The narrowing occurs because once the inflammatory response is triggered by an irritant, histamines, immunoglobulin E antibodies, and leukotrienes are released. Because of this, mucous production occurs. Since the bronchioles are inflamed and narrow, breathing becomes difficult. Wheezing sounds can be heard due to the lack of air being able to easily move in and out of the narrowed bronchioles.

Childhood asthma impacts scores of youngsters and their families. In fact, the bulk of kids develop respiratory illness before the age of